Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal imaging data of optical coherence tomography (OCT). To address the data scarcity issue, this paper proposes two solutions. First, we develop a novel generalization-reinforced semi-supervised learning (SSL) model called pseudo supervisor to optimally utilize unlabeled data. Compared with SOTA models, the proposed pseudo supervisor optimizes the policy of predicting pseudo labels with unlabeled samples to improve empirical generalization. Our pseudo supervisor model is evaluated with two clinical tasks consisting of glaucoma detection and progression forecasting. The progression forecasting task is evaluated both unimodally and multimodally. Our pseudo supervisor model demonstrates superior performance than SOTA SSL comparison models. Moreover, our model also achieves the best results on the publicly available LAG fundus dataset. Second, we introduce the Harvard Glaucoma Detection and Progression (Harvard-GDP) Dataset, a multimodal multitask dataset that includes data from 1,000 patients with OCT imaging data, as well as labels for glaucoma detection and progression. This is the largest glaucoma detection dataset with 3D OCT imaging data and the first glaucoma progression forecasting dataset that is publicly available. Detailed sex and racial analysis are provided, which can be used by interested researchers for fairness learning studies. Our released dataset is benchmarked with several SOTA supervised CNN and transformer deep learning models. The dataset and code are made publicly available via \url{//ophai.hms.harvard.edu/datasets/harvard-gdp1000}.
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The composite quantile regression (CQR) was introduced by Zou and Yuan [Ann. Statist. 36 (2008) 1108--1126] as a robust regression method for linear models with heavy-tailed errors while achieving high efficiency. Its penalized counterpart for high-dimensional sparse models was recently studied in Gu and Zou [IEEE Trans. Inf. Theory 66 (2020) 7132--7154], along with a specialized optimization algorithm based on the alternating direct method of multipliers (ADMM). Compared to the various first-order algorithms for penalized least squares, ADMM-based algorithms are not well-adapted to large-scale problems. To overcome this computational hardness, in this paper we employ a convolution-smoothed technique to CQR, complemented with iteratively reweighted $\ell_1$-regularization. The smoothed composite loss function is convex, twice continuously differentiable, and locally strong convex with high probability. We propose a gradient-based algorithm for penalized smoothed CQR via a variant of the majorize-minimization principal, which gains substantial computational efficiency over ADMM. Theoretically, we show that the iteratively reweighted $\ell_1$-penalized smoothed CQR estimator achieves near-minimax optimal convergence rate under heavy-tailed errors without any moment constraint, and further achieves near-oracle convergence rate under a weaker minimum signal strength condition than needed in Gu and Zou (2020). Numerical studies demonstrate that the proposed method exhibits significant computational advantages without compromising statistical performance compared to two state-of-the-art methods that achieve robustness and high efficiency simultaneously.
Vehicle-to-Everything (V2X) collaborative perception is crucial for autonomous driving. However, achieving high-precision V2X perception requires a significant amount of annotated real-world data, which can always be expensive and hard to acquire. Simulated data have raised much attention since they can be massively produced at an extremely low cost. Nevertheless, the significant domain gap between simulated and real-world data, including differences in sensor type, reflectance patterns, and road surroundings, often leads to poor performance of models trained on simulated data when evaluated on real-world data. In addition, there remains a domain gap between real-world collaborative agents, e.g. different types of sensors may be installed on autonomous vehicles and roadside infrastructures with different extrinsics, further increasing the difficulty of sim2real generalization. To take full advantage of simulated data, we present a new unsupervised sim2real domain adaptation method for V2X collaborative detection named Decoupled Unsupervised Sim2Real Adaptation (DUSA). Our new method decouples the V2X collaborative sim2real domain adaptation problem into two sub-problems: sim2real adaptation and inter-agent adaptation. For sim2real adaptation, we design a Location-adaptive Sim2Real Adapter (LSA) module to adaptively aggregate features from critical locations of the feature map and align the features between simulated data and real-world data via a sim/real discriminator on the aggregated global feature. For inter-agent adaptation, we further devise a Confidence-aware Inter-agent Adapter (CIA) module to align the fine-grained features from heterogeneous agents under the guidance of agent-wise confidence maps. Experiments demonstrate the effectiveness of the proposed DUSA approach on unsupervised sim2real adaptation from the simulated V2XSet dataset to the real-world DAIR-V2X-C dataset.
This work identifies a simple pre-training mechanism that leads to representations exhibiting better continual and transfer learning. This mechanism -- the repeated resetting of weights in the last layer, which we nickname "zapping" -- was originally designed for a meta-continual-learning procedure, yet we show it is surprisingly applicable in many settings beyond both meta-learning and continual learning. In our experiments, we wish to transfer a pre-trained image classifier to a new set of classes, in a few shots. We show that our zapping procedure results in improved transfer accuracy and/or more rapid adaptation in both standard fine-tuning and continual learning settings, while being simple to implement and computationally efficient. In many cases, we achieve performance on par with state of the art meta-learning without needing the expensive higher-order gradients, by using a combination of zapping and sequential learning. An intuitive explanation for the effectiveness of this zapping procedure is that representations trained with repeated zapping learn features that are capable of rapidly adapting to newly initialized classifiers. Such an approach may be considered a computationally cheaper type of, or alternative to, meta-learning rapidly adaptable features with higher-order gradients. This adds to recent work on the usefulness of resetting neural network parameters during training, and invites further investigation of this mechanism.
Generative Large Language Models (LLMs) such as GPT-3 are capable of generating highly fluent responses to a wide variety of user prompts. However, LLMs are known to hallucinate facts and make non-factual statements which can undermine trust in their output. Existing fact-checking approaches either require access to the output probability distribution (which may not be available for systems such as ChatGPT) or external databases that are interfaced via separate, often complex, modules. In this work, we propose "SelfCheckGPT", a simple sampling-based approach that can be used to fact-check the responses of black-box models in a zero-resource fashion, i.e. without an external database. SelfCheckGPT leverages the simple idea that if an LLM has knowledge of a given concept, sampled responses are likely to be similar and contain consistent facts. However, for hallucinated facts, stochastically sampled responses are likely to diverge and contradict one another. We investigate this approach by using GPT-3 to generate passages about individuals from the WikiBio dataset, and manually annotate the factuality of the generated passages. We demonstrate that SelfCheckGPT can: i) detect non-factual and factual sentences; and ii) rank passages in terms of factuality. We compare our approach to several baselines and show that our approach has considerably higher AUC-PR scores in sentence-level hallucination detection and higher correlation scores in passage-level factuality assessment compared to grey-box methods.
We consider the online planning problem for a team of agents to discover and track an unknown and time-varying number of moving objects from onboard sensor measurements with uncertain measurement-object origins. Since the onboard sensors have a limited field-of-view, the usual planning strategy based solely on either tracking detected objects or discovering unseen objects is inadequate. To address this, we formulate a new information-based multi-objective multi-agent control problem, cast as a partially observable Markov decision process (POMDP). The resulting multi-agent planning problem is exponentially complex due to the unknown data association between objects and multi-sensor measurements; hence, computing an optimal control action is intractable. We prove that the proposed multi-objective value function is a monotone submodular set function, which admits low-cost suboptimal solutions via greedy search with a tight optimality bound. The resulting planning algorithm has a linear complexity in the number of objects and measurements across the sensors, and quadratic in the number of agents. We demonstrate the proposed solution via a series of numerical experiments with a real-world dataset.
Integrated sensing and communication (ISAC) has the advantages of efficient spectrum utilization and low hardware cost. It is promising to be implemented in the fifth-generation-advanced (5G-A) and sixth-generation (6G) mobile communication systems, having the potential to be applied in intelligent applications requiring both communication and high-accurate sensing capabilities. As the fundamental technology of ISAC, ISAC signal directly impacts the performance of sensing and communication. This article systematically reviews the literature on ISAC signals from the perspective of mobile communication systems, including ISAC signal design, ISAC signal processing algorithms and ISAC signal optimization. We first review the ISAC signal design based on 5G, 5G-A and 6G mobile communication systems. Then, radar signal processing methods are reviewed for ISAC signals, mainly including the channel information matrix method, spectrum lines estimator method and super resolution method. In terms of signal optimization, we summarize peak-to-average power ratio (PAPR) optimization, interference management, and adaptive signal optimization for ISAC signals. This article may provide the guidelines for the research of ISAC signals in 5G-A and 6G mobile communication systems.
Systems for making determinations on socially-constructed and complex concepts at scale are increasingly being deployed. To make such fuzzy concepts tractable for training and evaluating AI, aligning model outputs, or human-in-the-loop workflows, the prevailing strategy involves developing `constitutions' in the form of rules, policies, or principles. However, high-level rules often fail to capture situational nuances or have differing interpretations, resulting in inconsistent decisions. In this work, we introduce case law grounding (CLG), a hybrid workflow inspired by case law in the legal realm where past judgments on specific cases inform new decisions. Evaluating on two task domains, we find that CLG can improve alignment of decisions (+9.6% and +10.9% accuracy) and consistency ($\Delta\bar{\kappa}$ of +0.263 and +0.433) of human decision-makers, while also providing auditable rationales. We also find similarly substantial alignment improvements for an LLM decision-maker (+25% and +23% accuracy).
Images can convey rich semantics and induce various emotions in viewers. Recently, with the rapid advancement of emotional intelligence and the explosive growth of visual data, extensive research efforts have been dedicated to affective image content analysis (AICA). In this survey, we will comprehensively review the development of AICA in the recent two decades, especially focusing on the state-of-the-art methods with respect to three main challenges -- the affective gap, perception subjectivity, and label noise and absence. We begin with an introduction to the key emotion representation models that have been widely employed in AICA and description of available datasets for performing evaluation with quantitative comparison of label noise and dataset bias. We then summarize and compare the representative approaches on (1) emotion feature extraction, including both handcrafted and deep features, (2) learning methods on dominant emotion recognition, personalized emotion prediction, emotion distribution learning, and learning from noisy data or few labels, and (3) AICA based applications. Finally, we discuss some challenges and promising research directions in the future, such as image content and context understanding, group emotion clustering, and viewer-image interaction.
Promoting behavioural diversity is critical for solving games with non-transitive dynamics where strategic cycles exist, and there is no consistent winner (e.g., Rock-Paper-Scissors). Yet, there is a lack of rigorous treatment for defining diversity and constructing diversity-aware learning dynamics. In this work, we offer a geometric interpretation of behavioural diversity in games and introduce a novel diversity metric based on \emph{determinantal point processes} (DPP). By incorporating the diversity metric into best-response dynamics, we develop \emph{diverse fictitious play} and \emph{diverse policy-space response oracle} for solving normal-form games and open-ended games. We prove the uniqueness of the diverse best response and the convergence of our algorithms on two-player games. Importantly, we show that maximising the DPP-based diversity metric guarantees to enlarge the \emph{gamescape} -- convex polytopes spanned by agents' mixtures of strategies. To validate our diversity-aware solvers, we test on tens of games that show strong non-transitivity. Results suggest that our methods achieve much lower exploitability than state-of-the-art solvers by finding effective and diverse strategies.
Multi-agent influence diagrams (MAIDs) are a popular form of graphical model that, for certain classes of games, have been shown to offer key complexity and explainability advantages over traditional extensive form game (EFG) representations. In this paper, we extend previous work on MAIDs by introducing the concept of a MAID subgame, as well as subgame perfect and trembling hand perfect equilibrium refinements. We then prove several equivalence results between MAIDs and EFGs. Finally, we describe an open source implementation for reasoning about MAIDs and computing their equilibria.
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