Neuromorphic computing is one of the few current approaches that have the potential to significantly reduce power consumption in Machine Learning and Artificial Intelligence. Imam & Cleland presented an odour-learning algorithm that runs on a neuromorphic architecture and is inspired by circuits described in the mammalian olfactory bulb. They assess the algorithm's performance in "rapid online learning and identification" of gaseous odorants and odorless gases (short "gases") using a set of gas sensor recordings of different odour presentations and corrupting them by impulse noise. We replicated parts of the study and discovered limitations that affect some of the conclusions drawn. First, the dataset used suffers from sensor drift and a non-randomised measurement protocol, rendering it of limited use for odour identification benchmarks. Second, we found that the model is restricted in its ability to generalise over repeated presentations of the same gas. We demonstrate that the task the study refers to can be solved with a simple hash table approach, matching or exceeding the reported results in accuracy and runtime. Therefore, a validation of the model that goes beyond restoring a learned data sample remains to be shown, in particular its suitability to odour identification tasks.
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Batch effects are pervasive in biomedical studies. One approach to address the batch effects is repeatedly measuring a subset of samples in each batch. These remeasured samples are used to estimate and correct the batch effects. However, rigorous statistical methods for batch effect correction with remeasured samples are severely under-developed. In this study, we developed a framework for batch effect correction using remeasured samples in highly confounded case-control studies. We provided theoretical analyses of the proposed procedure, evaluated its power characteristics, and provided a power calculation tool to aid in the study design. We found that the number of samples that need to be remeasured depends strongly on the between-batch correlation. When the correlation is high, remeasuring a small subset of samples is possible to rescue most of the power.
Scale-free dynamics, formalized by selfsimilarity, provides a versatile paradigm massively and ubiquitously used to model temporal dynamics in real-world data. However, its practical use has mostly remained univariate so far. By contrast, modern applications often demand multivariate data analysis. Accordingly, models for multivariate selfsimilarity were recently proposed. Nevertheless, they have remained rarely used in practice because of a lack of available robust estimation procedures for the vector of selfsimilarity parameters. Building upon recent mathematical developments, the present work puts forth an efficient estimation procedure based on the theoretical study of the multiscale eigenstructure of the wavelet spectrum of multivariate selfsimilar processes. The estimation performance is studied theoretically in the asymptotic limits of large scale and sample sizes, and computationally for finite-size samples. As a practical outcome, a fully operational and documented multivariate signal processing estimation toolbox is made freely available and is ready for practical use on real-world data. Its potential benefits are illustrated in epileptic seizure prediction from multi-channel EEG data.
We propose a data-driven approach to explicitly learn the progressive encoding of a continuous source, which is successively decoded with increasing levels of quality and with the aid of correlated side information. This setup refers to the successive refinement of the Wyner-Ziv coding problem. Assuming ideal Slepian-Wolf coding, our approach employs recurrent neural networks (RNNs) to learn layered encoders and decoders for the quadratic Gaussian case. The models are trained by minimizing a variational bound on the rate-distortion function of the successively refined Wyner-Ziv coding problem. We demonstrate that RNNs can explicitly retrieve layered binning solutions akin to scalable nested quantization. Moreover, the rate-distortion performance of the scheme is on par with the corresponding monolithic Wyner-Ziv coding approach and is close to the rate-distortion bound.
As quantum theory allows for information processing and computing tasks that otherwise are not possible with classical systems, there is a need and use of quantum Internet beyond existing network systems. At the same time, the realization of a desirably functional quantum Internet is hindered by fundamental and practical challenges such as high loss during transmission of quantum systems, decoherence due to interaction with the environment, fragility of quantum states, etc. We study the implications of these constraints by analyzing the limitations on the scaling and robustness of quantum Internet. Considering quantum networks, we present practical bottlenecks for secure communication, delegated computing, and resource distribution among end nodes. Motivated by the power of abstraction in graph theory (in association with quantum information theory), we consider graph-theoretic quantifiers to assess network robustness and provide critical values of communication lines for viable communication over quantum Internet. In particular, we begin by discussing limitations on usefulness of isotropic states as device-independent quantum key repeaters which otherwise could be useful for device-independent quantum key distribution. We consider some quantum networks of practical interest, ranging from satellite-based networks connecting far-off spatial locations to currently available quantum processor architectures within computers, and analyze their robustness to perform quantum information processing tasks. Some of these tasks form primitives for delegated quantum computing, e.g., entanglement distribution and quantum teleportation. For some examples of quantum networks, we present algorithms to perform different quantum network tasks of interest such as constructing the network structure, finding the shortest path between a pair of end nodes, and optimizing the flow of resources at a node.
Quantum computing has recently emerged as a transformative technology. Yet, its promised advantages rely on efficiently translating quantum operations into viable physical realizations. In this work, we use generative machine learning models, specifically denoising diffusion models (DMs), to facilitate this transformation. Leveraging text-conditioning, we steer the model to produce desired quantum operations within gate-based quantum circuits. Notably, DMs allow to sidestep during training the exponential overhead inherent in the classical simulation of quantum dynamics -- a consistent bottleneck in preceding ML techniques. We demonstrate the model's capabilities across two tasks: entanglement generation and unitary compilation. The model excels at generating new circuits and supports typical DM extensions such as masking and editing to, for instance, align the circuit generation to the constraints of the targeted quantum device. Given their flexibility and generalization abilities, we envision DMs as pivotal in quantum circuit synthesis, enhancing both practical applications but also insights into theoretical quantum computation.
In prediction settings where data are collected over time, it is often of interest to understand both the importance of variables for predicting the response at each time point and the importance summarized over the time series. Building on recent advances in estimation and inference for variable importance measures, we define summaries of variable importance trajectories. These measures can be estimated and the same approaches for inference can be applied regardless of the choice of the algorithm(s) used to estimate the prediction function. We propose a nonparametric efficient estimation and inference procedure as well as a null hypothesis testing procedure that are valid even when complex machine learning tools are used for prediction. Through simulations, we demonstrate that our proposed procedures have good operating characteristics, and we illustrate their use by investigating the longitudinal importance of risk factors for suicide attempt.
Quantum error correction is crucial for scalable quantum information processing applications. Traditional discrete-variable quantum codes that use multiple two-level systems to encode logical information can be hardware-intensive. An alternative approach is provided by bosonic codes, which use the infinite-dimensional Hilbert space of harmonic oscillators to encode quantum information. Two promising features of bosonic codes are that syndrome measurements are natively analog and that they can be concatenated with discrete-variable codes. In this work, we propose novel decoding methods that explicitly exploit the analog syndrome information obtained from the bosonic qubit readout in a concatenated architecture. Our methods are versatile and can be generally applied to any bosonic code concatenated with a quantum low-density parity-check (QLDPC) code. Furthermore, we introduce the concept of quasi-single-shot protocols as a novel approach that significantly reduces the number of repeated syndrome measurements required when decoding under phenomenological noise. To realize the protocol, we present a first implementation of time-domain decoding with the overlapping window method for general QLDPC codes, and a novel analog single-shot decoding method. Our results lay the foundation for general decoding algorithms using analog information and demonstrate promising results in the direction of fault-tolerant quantum computation with concatenated bosonic-QLDPC codes.
We study the numerical approximation of a coupled hyperbolic-parabolic system by a family of discontinuous Galerkin space-time finite element methods. The model is rewritten as a first-order evolutionary problem that is treated by the unified abstract solution theory of R.\ Picard. To preserve the mathematical structure of the evolutionary equation on the fully discrete level, suitable generalizations of the distribution gradient and divergence operators on broken polynomial spaces on which the discontinuous Galerkin approach is built on are defined. Well-posedness of the fully discrete problem and error estimates for the discontinuous Galerkin approximation in space and time are proved.
We show a deterministic constant-time local algorithm for constructing an approximately maximum flow and minimum fractional cut in multisource-multitarget networks with bounded degrees and bounded edge capacities. Locality means that the decision we make about each edge only depends on its constant radius neighborhood. We show two applications of the algorithms: one is related to the Aldous-Lyons Conjecture, and the other is about approximating the neighborhood distribution of graphs by bounded-size graphs. The scope of our results can be extended to unimodular random graphs and networks. As a corollary, we generalize the Maximum Flow Minimum Cut Theorem to unimodular random flow networks.
In sampling-based Bayesian models of brain function, neural activities are assumed to be samples from probability distributions that the brain uses for probabilistic computation. However, a comprehensive understanding of how mechanistic models of neural dynamics can sample from arbitrary distributions is still lacking. We use tools from functional analysis and stochastic differential equations to explore the minimum architectural requirements for $\textit{recurrent}$ neural circuits to sample from complex distributions. We first consider the traditional sampling model consisting of a network of neurons whose outputs directly represent the samples (sampler-only network). We argue that synaptic current and firing-rate dynamics in the traditional model have limited capacity to sample from a complex probability distribution. We show that the firing rate dynamics of a recurrent neural circuit with a separate set of output units can sample from an arbitrary probability distribution. We call such circuits reservoir-sampler networks (RSNs). We propose an efficient training procedure based on denoising score matching that finds recurrent and output weights such that the RSN implements Langevin sampling. We empirically demonstrate our model's ability to sample from several complex data distributions using the proposed neural dynamics and discuss its applicability to developing the next generation of sampling-based brain models.
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