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Federated Learning (FL) has emerged as a new paradigm for training machine learning models distributively without sacrificing data security and privacy. Learning models on edge devices such as mobile phones is one of the most common use cases for FL. However, Non-identical independent distributed~(non-IID) data in edge devices easily leads to training failures. Especially, over-parameterized machine learning models can easily be over-fitted on such data, hence, resulting in inefficient federated learning and poor model performance. To overcome the over-fitting issue, we proposed an adaptive dynamic pruning approach for FL, which can dynamically slim the model by dropping out unimportant parameters, hence, preventing over-fittings. Since the machine learning model's parameters react differently for different training samples, adaptive dynamic pruning will evaluate the salience of the model's parameter according to the input training sample, and only retain the salient parameter's gradients when doing back-propagation. We performed comprehensive experiments to evaluate our approach. The results show that our approach by removing the redundant parameters in neural networks can significantly reduce the over-fitting issue and greatly improves the training efficiency. In particular, when training the ResNet-32 on CIFAR-10, our approach reduces the communication cost by 57\%. We further demonstrate the inference acceleration capability of the proposed algorithm. Our approach reduces up to 50\% FLOPs inference of DNNs on edge devices while maintaining the model's quality.

We study a variant of online convex optimization where the player is permitted to switch decisions at most $S$ times in expectation throughout $T$ rounds. Similar problems have been addressed in prior work for the discrete decision set setting, and more recently in the continuous setting but only with an adaptive adversary. In this work, we aim to fill the gap and present computationally efficient algorithms in the more prevalent oblivious setting, establishing a regret bound of $O(T/S)$ for general convex losses and $\widetilde O(T/S^2)$ for strongly convex losses. In addition, for stochastic i.i.d.~losses, we present a simple algorithm that performs $\log T$ switches with only a multiplicative $\log T$ factor overhead in its regret in both the general and strongly convex settings. Finally, we complement our algorithms with lower bounds that match our upper bounds in some of the cases we consider.

In day-ahead electricity markets based on uniform marginal pricing, small variations in the offering and bidding curves may substantially modify the resulting market outcomes. In this work, we deal with the problem of finding the optimal offering curve for a risk-averse profit-maximizing generating company (GENCO) in a data-driven context. In particular, a large GENCO's market share may imply that her offering strategy can alter the marginal price formation, which can be used to increase profit. We tackle this problem from a novel perspective. First, we propose a optimization-based methodology to summarize each GENCO's step-wise supply curves into a subset of representative price-energy blocks. Then, the relationship between the market price and the resulting energy block offering prices is modeled through a Bayesian linear regression approach, which also allows us to generate stochastic scenarios for the sensibility of the market towards the GENCO strategy, represented by the regression coefficient probabilistic distributions. Finally, this predictive model is embedded in the stochastic optimization model by employing a constraint learning approach. Results show how allowing the GENCO to deviate from her true marginal costs renders significant changes in her profits and the market marginal price. Furthermore, these results have also been tested in an out-of-sample validation setting, showing how this optimal offering strategy is also effective in a real-world market contest.

The two-sample problem consists in testing whether two independent samples are drawn from the same (unknown) probability distribution. It finds applications in many areas, ranging from clinical trials to data attribute matching. Its study in high-dimension is the subject of much attention, in particular as the information acquisition processes can involve various sources being often poorly controlled, possibly leading to datasets with strong sampling bias that may jeopardize their statistical analysis. While classic methods relying on a discrepancy measure between empirical versions of the distributions face the curse of dimensionality, we develop an alternative approach based on statistical learning and extending rank tests, known to be asymptotically optimal for univariate data when appropriately designed. Overcoming the lack of natural order on high-dimension, it is implemented in two steps. Assigning a label to each sample, and dividing them into two halves, a preorder on the feature space defined by a real-valued scoring function is learned by a bipartite ranking algorithm applied to the first halves. Next, a two-sample homogeneity rank test is applied to the (univariate) scores of the remaining observations. Because it learns how to map the data onto the real line like (any monotone transform of) the likelihood ratio between the original multivariate distributions, the approach is not affected by the dimensionality, ignores ranking model bias issues, and preserves the asymptotic optimality of univariate R-tests, capable of detecting small departures from the null assumption. Beyond a theoretical analysis establishing nonasymptotic bounds for the two types of error of the method based on recent concentration results for two-sample linear R-processes, an extensive experimental study shows higher performance of the proposed method compared to classic ones.

Process design is a creative task that is currently performed manually by engineers. Artificial intelligence provides new potential to facilitate process design. Specifically, reinforcement learning (RL) has shown some success in automating process design by integrating data-driven models that learn to build process flowsheets with process simulation in an iterative design process. However, one major challenge in the learning process is that the RL agent demands numerous process simulations in rigorous process simulators, thereby requiring long simulation times and expensive computational power. Therefore, typically short-cut simulation methods are employed to accelerate the learning process. Short-cut methods can, however, lead to inaccurate results. We thus propose to utilize transfer learning for process design with RL in combination with rigorous simulation methods. Transfer learning is an established approach from machine learning that stores knowledge gained while solving one problem and reuses this information on a different target domain. We integrate transfer learning in our RL framework for process design and apply it to an illustrative case study comprising equilibrium reactions, azeotropic separation, and recycles, our method can design economically feasible flowsheets with stable interaction with DWSIM. Our results show that transfer learning enables RL to economically design feasible flowsheets with DWSIM, resulting in a flowsheet with an 8% higher revenue. And the learning time can be reduced by a factor of 2.

Federated learning methods, that is, methods that perform model training using data situated across different sources, whilst simultaneously not having the data leave their original source, are of increasing interest in a number of fields. However, despite this interest, the classes of models for which easily-applicable and sufficiently general approaches are available is limited, excluding many structured probabilistic models. We present a general yet elegant resolution to the aforementioned issue. The approach is based on adopting structured variational inference, an approach widely used in Bayesian machine learning, to the federated setting. Additionally, a communication-efficient variant analogous to the canonical FedAvg algorithm is explored. The effectiveness of the proposed algorithms are demonstrated, and their performance is compared on Bayesian multinomial regression, topic modelling, and mixed model examples.

We create a mixed-integer optimization (MIO) approach for doing cluster-aware regression, i.e. linear regression that takes into account the inherent clustered structure of the data. We compare to the linear mixed effects regression (LMEM) which is the most used current method, and design simulation experiments to show superior performance to LMEM in terms of both predictive and inferential metrics in silico. Furthermore, we show how our method is formulated in a very interpretable way; LMEM cannot generalize and make cluster-informed predictions when the cluster of new data points is unknown, but we solve this problem by training an interpretable classification tree that can help decide cluster effects for new data points, and demonstrate the power of this generalizability on a real protein expression dataset.

Bid optimization for online advertising from single advertiser's perspective has been thoroughly investigated in both academic research and industrial practice. However, existing work typically assume competitors do not change their bids, i.e., the wining price is fixed, leading to poor performance of the derived solution. Although a few studies use multi-agent reinforcement learning to set up a cooperative game, they still suffer the following drawbacks: (1) They fail to avoid collusion solutions where all the advertisers involved in an auction collude to bid an extremely low price on purpose. (2) Previous works cannot well handle the underlying complex bidding environment, leading to poor model convergence. This problem could be amplified when handling multiple objectives of advertisers which are practical demands but not considered by previous work. In this paper, we propose a novel multi-objective cooperative bid optimization formulation called Multi-Agent Cooperative bidding Games (MACG). MACG sets up a carefully designed multi-objective optimization framework where different objectives of advertisers are incorporated. A global objective to maximize the overall profit of all advertisements is added in order to encourage better cooperation and also to protect self-bidding advertisers. To avoid collusion, we also introduce an extra platform revenue constraint. We analyze the optimal functional form of the bidding formula theoretically and design a policy network accordingly to generate auction-level bids. Then we design an efficient multi-agent evolutionary strategy for model optimization. Offline experiments and online A/B tests conducted on the Taobao platform indicate both single advertiser's objective and global profit have been significantly improved compared to state-of-art methods.

Applying artificial intelligence techniques in medical imaging is one of the most promising areas in medicine. However, most of the recent success in this area highly relies on large amounts of carefully annotated data, whereas annotating medical images is a costly process. In this paper, we propose a novel method, called FocalMix, which, to the best of our knowledge, is the first to leverage recent advances in semi-supervised learning (SSL) for 3D medical image detection. We conducted extensive experiments on two widely used datasets for lung nodule detection, LUNA16 and NLST. Results show that our proposed SSL methods can achieve a substantial improvement of up to 17.3% over state-of-the-art supervised learning approaches with 400 unlabeled CT scans.

Breast cancer remains a global challenge, causing over 1 million deaths globally in 2018. To achieve earlier breast cancer detection, screening x-ray mammography is recommended by health organizations worldwide and has been estimated to decrease breast cancer mortality by 20-40%. Nevertheless, significant false positive and false negative rates, as well as high interpretation costs, leave opportunities for improving quality and access. To address these limitations, there has been much recent interest in applying deep learning to mammography; however, obtaining large amounts of annotated data poses a challenge for training deep learning models for this purpose, as does ensuring generalization beyond the populations represented in the training dataset. Here, we present an annotation-efficient deep learning approach that 1) achieves state-of-the-art performance in mammogram classification, 2) successfully extends to digital breast tomosynthesis (DBT; "3D mammography"), 3) detects cancers in clinically-negative prior mammograms of cancer patients, 4) generalizes well to a population with low screening rates, and 5) outperforms five-out-of-five full-time breast imaging specialists by improving absolute sensitivity by an average of 14%. Our results demonstrate promise towards software that can improve the accuracy of and access to screening mammography worldwide.