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The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale signaling pathways and protein-protein interaction networks, yet they face limitations in expressivity when capturing intricate biological relationships. To address this, we propose Graph Sequence Language Model (GraphSeqLM), a framework that enhances GNNs with biological sequence embeddings generated by Large Language Models (LLMs). These embeddings encode structural and biological properties of DNA, RNA, and proteins, augmenting GNNs with enriched features for analyzing sample-specific multi-omic data. By integrating topological, sequence-derived, and biological information, GraphSeqLM demonstrates superior predictive accuracy and outperforms existing methods, paving the way for more effective multi-omic data integration in precision medicine.

As data volumes expand rapidly, distributed machine learning has become essential for addressing the growing computational demands of modern AI systems. However, training models in distributed environments is challenging with participants hold skew, Non-Independent-Identically distributed (Non-IID) data. Low-Rank Adaptation (LoRA) offers a promising solution to this problem by personalizing low-rank updates rather than optimizing the entire model, LoRA-enabled distributed learning minimizes computational and maximize personalization for each participant. Enabling more robust and efficient training in distributed learning settings, especially in large-scale, heterogeneous systems. Despite the strengths of current state-of-the-art methods, they often require manual configuration of the initial rank, which is increasingly impractical as the number of participants grows. This manual tuning is not only time-consuming but also prone to suboptimal configurations. To address this limitation, we propose AutoRank, an adaptive rank-setting algorithm inspired by the bias-variance trade-off. AutoRank leverages the MCDA method TOPSIS to dynamically assign local ranks based on the complexity of each participant's data. By evaluating data distribution and complexity through our proposed data complexity metrics, AutoRank provides fine-grained adjustments to the rank of each participant's local LoRA model. This adaptive approach effectively mitigates the challenges of double-imbalanced, non-IID data. Experimental results demonstrate that AutoRank significantly reduces computational overhead, enhances model performance, and accelerates convergence in highly heterogeneous federated learning environments. Through its strong adaptability, AutoRank offers a scalable and flexible solution for distributed machine learning.

Recommender systems are widely used in various real-world applications, but they often encounter the persistent challenge of the user cold-start problem. Cross-domain recommendation (CDR), which leverages user interactions from one domain to improve prediction performance in another, has emerged as a promising solution. However, users with similar preferences in the source domain may exhibit different interests in the target domain. Therefore, directly transferring embeddings may introduce irrelevant source-domain collaborative information. In this paper, we propose a novel graph-based disentangled contrastive learning framework to capture fine-grained user intent and filter out irrelevant collaborative information, thereby avoiding negative transfer. Specifically, for each domain, we use a multi-channel graph encoder to capture diverse user intents. We then construct the affinity graph in the embedding space and perform multi-step random walks to capture high-order user similarity relationships. Treating one domain as the target, we propose a disentangled intent-wise contrastive learning approach, guided by user similarity, to refine the bridging of user intents across domains. Extensive experiments on four benchmark CDR datasets demonstrate that DisCo consistently outperforms existing state-of-the-art baselines, thereby validating the effectiveness of both DisCo and its components.

Although multiview fusion has demonstrated potential in LiDAR segmentation, its dependence on computationally intensive point-based interactions, arising from the lack of fixed correspondences between views such as range view and Bird's-Eye View (BEV), hinders its practical deployment. This paper challenges the prevailing notion that multiview fusion is essential for achieving high performance. We demonstrate that significant gains can be realized by directly fusing Polar and Cartesian partitioning strategies within the BEV space. Our proposed BEV-only segmentation model leverages the inherent fixed grid correspondences between these partitioning schemes, enabling a fusion process that is orders of magnitude faster (170$\times$ speedup) than conventional point-based methods. Furthermore, our approach facilitates dense feature fusion, preserving richer contextual information compared to sparse point-based alternatives. To enhance scene understanding while maintaining inference efficiency, we also introduce a hybrid Transformer-CNN architecture. Extensive evaluation on the SemanticKITTI and nuScenes datasets provides compelling evidence that our method outperforms previous multiview fusion approaches in terms of both performance and inference speed, highlighting the potential of BEV-based fusion for LiDAR segmentation. Code is available at \url{//github.com/skyshoumeng/PC-BEV.}

Due to the sensitivity of data, Federated Learning (FL) is employed to enable distributed machine learning while safeguarding data privacy and accommodating the requirements of various devices. However, in the context of semi-decentralized FL, clients' communication and training states are dynamic. This variability arises from local training fluctuations, heterogeneous data distributions, and intermittent client participation. Most existing studies primarily focus on stable client states, neglecting the dynamic challenges inherent in real-world scenarios. To tackle this issue, we propose a TRust-Aware clIent scheduLing mechanism called TRAIL, which assesses client states and contributions, enhancing model training efficiency through selective client participation. We focus on a semi-decentralized FL framework where edge servers and clients train a shared global model using unreliable intra-cluster model aggregation and inter-cluster model consensus. First, we propose an adaptive hidden semi-Markov model to estimate clients' communication states and contributions. Next, we address a client-server association optimization problem to minimize global training loss. Using convergence analysis, we propose a greedy client scheduling algorithm. Finally, our experiments conducted on real-world datasets demonstrate that TRAIL outperforms state-of-the-art baselines, achieving an improvement of 8.7% in test accuracy and a reduction of 15.3% in training loss.

Software testing is a crucial but time-consuming aspect of software development, and recently, Large Language Models (LLMs) have gained popularity for automated test case generation. However, because LLMs are trained on vast amounts of open-source code, they often generate test cases that do not adhere to best practices and may even contain test smells (anti-patterns). To address this issue, we propose Reinforcement Learning from Static Quality Metrics (RLSQM), wherein we utilize Reinforcement Learning to generate high-quality unit tests based on static analysis-based quality metrics. First, we analyzed LLM-generated tests and show that LLMs frequently do generate undesirable test smells -- up to 37% of the time. Then, we implemented lightweight static analysis-based reward model and trained LLMs using this reward model to optimize for five code quality metrics. Our experimental results demonstrate that the RL-optimized Codex model consistently generated higher-quality test cases than the base LLM, improving quality metrics by up to 23%, and generated nearly 100% syntactically-correct code. RLSQM also outperformed GPT-4 on all code quality metrics, in spite of training a substantially cheaper Codex model. We provide insights into how reliably utilize RL to improve test generation quality and show that RLSQM is a significant step towards enhancing the overall efficiency and reliability of automated software testing. Our data are available at //doi.org/10.6084/m9.figshare.25983166.

Formal verification using proof assistants, such as Coq, enables the creation of high-quality software. However, the verification process requires significant expertise and manual effort to write proofs. Recent work has explored automating proof synthesis using machine learning and large language models (LLMs). This work has shown that identifying relevant premises, such as lemmas and definitions, can aid synthesis. We present Rango, a fully automated proof synthesis tool for Coq that automatically identifies relevant premises and also similar proofs from the current project and uses them during synthesis. Rango uses retrieval augmentation at every step of the proof to automatically determine which proofs and premises to include in the context of its fine-tuned LLM. In this way, Rango adapts to the project and to the evolving state of the proof. We create a new dataset, CoqStoq, of 2,226 open-source Coq projects and 196,929 theorems from GitHub, which includes both training data and a curated evaluation benchmark of well-maintained projects. On this benchmark, Rango synthesizes proofs for 32.0% of the theorems, which is 29% more theorems than the prior state-of-the-art tool Tactician. Our evaluation also shows that Rango adding relevant proofs to its context leads to a 47% increase in the number of theorems proven.

Accurate and comprehensive 3D sensing using LiDAR systems is crucial for various applications in photogrammetry and robotics, including facility inspection, Building Information Modeling (BIM), and robot navigation. Motorized LiDAR systems can expand the Field of View (FoV) without adding multiple scanners, but existing motorized LiDAR systems often rely on constant-speed motor control, leading to suboptimal performance in complex environments. To address this, we propose UA-MPC, an uncertainty-aware motor control strategy that balances scanning accuracy and efficiency. By predicting discrete observabilities of LiDAR Odometry (LO) through ray tracing and modeling their distribution with a surrogate function, UA-MPC efficiently optimizes motor speed control according to different scenes. Additionally, we develop a ROS-based realistic simulation environment for motorized LiDAR systems, enabling the evaluation of control strategies across diverse scenarios. Extensive experiments, conducted on both simulated and real-world scenarios, demonstrate that our method significantly improves odometry accuracy while preserving the scanning efficiency of motorized LiDAR systems. Specifically, it achieves over a 60\% reduction in positioning error with less than a 2\% decrease in efficiency compared to constant-speed control, offering a smarter and more effective solution for active 3D sensing tasks. The simulation environment for control motorized LiDAR is open-sourced at: \url{//github.com/kafeiyin00/UA-MPC.git}.

The cross-domain recommendation technique is an effective way of alleviating the data sparsity in recommender systems by leveraging the knowledge from relevant domains. Transfer learning is a class of algorithms underlying these techniques. In this paper, we propose a novel transfer learning approach for cross-domain recommendation by using neural networks as the base model. We assume that hidden layers in two base networks are connected by cross mappings, leading to the collaborative cross networks (CoNet). CoNet enables dual knowledge transfer across domains by introducing cross connections from one base network to another and vice versa. CoNet is achieved in multi-layer feedforward networks by adding dual connections and joint loss functions, which can be trained efficiently by back-propagation. The proposed model is evaluated on two real-world datasets and it outperforms baseline models by relative improvements of 3.56\% in MRR and 8.94\% in NDCG, respectively.