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A core challenge for superconducting quantum computers is to scale up the number of qubits in each processor without increasing noise or cross-talk. Distributing a quantum computer across nearby small qubit arrays, known as chiplets, could solve many problems associated with size. We propose a chiplet architecture over microwave links with potential to exceed monolithic performance on near-term hardware. We model and evaluate the chiplet architecture in a way that bridges the physical and network layers. We find concrete evidence that distributed quantum computing may accelerate the path toward useful and ultimately scalable quantum computers. In the long-term, short-range networks may underlie quantum computers just as local area networks underlie classical datacenters and supercomputers today.

Cross-Blockchain communication has gained traction due to the increasing fragmentation of blockchain networks and scalability solutions such as side-chaining and sharding. With SmartSync, we propose a novel concept for cross-blockchain smart contract interactions that creates client contracts on arbitrary blockchain networks supporting the same execution environment. Client contracts mirror the logic and state of the original instance and enable seamless on-chain function executions providing recent states. Synchronized contracts supply instant read-only function calls to other applications hosted on the target blockchain. Hereby, current limitations in cross-chain communication are alleviated and new forms of contract interactions are enabled. State updates are transmitted in a verifiable manner using Merkle proofs and do not require trusted intermediaries. To permit lightweight synchronizations, we introduce transition confirmations that facilitate the application of verifiable state transitions without re-executing transactions of the source blockchain. We prove the concept's soundness by providing a prototypical implementation that enables smart contract forks, state synchronizations, and on-chain validation on EVM-compatible blockchains. Our evaluation demonstrates SmartSync's applicability for presented use cases providing access to recent states to third-party contracts on the target blockchain. Execution costs scale sub-linearly with the number of value updates and depend on the depth and index of corresponding Merkle proofs.

This is a set of lecture notes used in a graduate topic class in applied mathematics called ``Quantum Algorithms for Scientific Computation'' at the Department of Mathematics, UC Berkeley during the fall semester of 2021. These lecture notes focus only on quantum algorithms closely related to scientific computation, and in particular, matrix computation. The main purpose of the lecture notes is to introduce quantum phase estimation (QPE) and ``post-QPE'' methods such as block encoding, quantum signal processing, and quantum singular value transformation, and to demonstrate their applications in solving eigenvalue problems, linear systems of equations, and differential equations. The intended audience is the broad computational science and engineering (CSE) community interested in using fault-tolerant quantum computers to solve challenging scientific computing problems.

When hyperparameter optimization of a machine learning algorithm is repeated for multiple datasets it is possible to transfer knowledge to an optimization run on a new dataset. We develop a new hyperparameter-free ensemble model for Bayesian optimization that is a generalization of two existing transfer learning extensions to Bayesian optimization and establish a worst-case bound compared to vanilla Bayesian optimization. Using a large collection of hyperparameter optimization benchmark problems, we demonstrate that our contributions substantially reduce optimization time compared to standard Gaussian process-based Bayesian optimization and improve over the current state-of-the-art for transfer hyperparameter optimization.

Quantum error mitigation (QEM) is a class of promising techniques for reducing the computational error of variational quantum algorithms. In general, the computational error reduction comes at the cost of a sampling overhead due to the variance-boosting effect caused by the channel inversion operation, which ultimately limits the applicability of QEM. Existing sampling overhead analysis of QEM typically assumes exact channel inversion, which is unrealistic in practical scenarios. In this treatise, we consider a practical channel inversion strategy based on Monte Carlo sampling, which introduces additional computational error that in turn may be eliminated at the cost of an extra sampling overhead. In particular, we show that when the computational error is small compared to the dynamic range of the error-free results, it scales with the square root of the number of gates. By contrast, the error exhibits a linear scaling with the number of gates in the absence of QEM under the same assumptions. Hence, the error scaling of QEM remains to be preferable even without the extra sampling overhead. Our analytical results are accompanied by numerical examples.

We give a classical algorithm for linear regression analogous to the quantum matrix inversion algorithm [Harrow, Hassidim, and Lloyd, Physical Review Letters'09, arXiv:0811.3171] for low-rank matrices [Wossnig, Zhao, and Prakash, Physical Review Letters'18, arXiv:1704.06174], when the input matrix $A$ is stored in a data structure applicable for QRAM-based state preparation. Namely, suppose we are given an $A \in \mathbb{C}^{m\times n}$ with minimum non-zero singular value $\sigma$ which supports certain efficient $\ell_2$-norm importance sampling queries, along with a $b \in \mathbb{C}^m$. Then, for some $x \in \mathbb{C}^n$ satisfying $\|x - A^+b\| \leq \varepsilon\|A^+b\|$, we can output a measurement of $|x\rangle$ in the computational basis and output an entry of $x$ with classical algorithms that run in $\tilde{\mathcal{O}}\big(\frac{\|A\|_{\mathrm{F}}^6\|A\|^6}{\sigma^{12}\varepsilon^4}\big)$ and $\tilde{\mathcal{O}}\big(\frac{\|A\|_{\mathrm{F}}^6\|A\|^2}{\sigma^8\varepsilon^4}\big)$ time, respectively. This improves on previous "quantum-inspired" algorithms in this line of research by at least a factor of $\frac{\|A\|^{16}}{\sigma^{16}\varepsilon^2}$ [Chia, Gily\'en, Li, Lin, Tang and Wang, STOC'20, arXiv:1910.06151]. As a consequence, we show that quantum computers can achieve at most a factor-of-12 speedup for linear regression in this QRAM data structure setting and related settings. Our work applies techniques from sketching algorithms and optimization to the quantum-inspired literature. Unlike earlier works, this is a promising avenue that could lead to feasible implementations of classical regression in a quantum-inspired settings, for comparison against future quantum computers.

We prove a lower bound on the probability of Shor's order-finding algorithm successfully recovering the order $r$ in a single run. The bound implies that by performing two limited searches in the classical post-processing part of the algorithm, a high success probability can be guaranteed, for any $r$, without re-running the quantum part or increasing the exponent length compared to Shor. Asymptotically, in the limit as $r$ tends to infinity, the probability of successfully recovering $r$ in a single run tends to one. Already for moderate $r$, a high success probability exceeding e.g. $1 - 10^{-4}$ can be guaranteed. As corollaries, we prove analogous results for the probability of completely factoring any integer $N$ in a single run of the order-finding algorithm.

Finding the closest separable state to a given target state is a notoriously difficult task, even more difficult than deciding whether a state is entangled or separable. To tackle this task, we parametrize separable states with a neural network and train it to minimize the distance to a given target state, with respect to a differentiable distance, such as the trace distance or Hilbert-Schmidt distance. By examining the output of the algorithm, we can deduce whether the target state is entangled or not, and construct an approximation for its closest separable state. We benchmark the method on a variety of well-known classes of bipartite states and find excellent agreement, even up to local dimension of $d=10$. Moreover, we show our method to be efficient in the multipartite case, considering different notions of separability. Examining three and four-party GHZ and W states we recover known bounds and obtain novel ones, for instance for triseparability. Finally, we show how to use the neural network's results to gain analytic insight.

Machine learning (ML) classification tasks can be carried out on a quantum computer (QC) using Probabilistic Quantum Memory (PQM) and its extension, Parameteric PQM (P-PQM) by calculating the Hamming distance between an input pattern and a database of $r$ patterns containing $z$ features with $a$ distinct attributes. For accurate computations, the feature must be encoded using one-hot encoding, which is memory-intensive for multi-attribute datasets with $a>2$. We can easily represent multi-attribute data more compactly on a classical computer by replacing one-hot encoding with label encoding. However, replacing these encoding schemes on a QC is not straightforward as PQM and P-PQM operate at the quantum bit level. We present an enhanced P-PQM, called EP-PQM, that allows label encoding of data stored in a PQM data structure and reduces the circuit depth of the data storage and retrieval procedures. We show implementations for an ideal QC and a noisy intermediate-scale quantum (NISQ) device. Our complexity analysis shows that the EP-PQM approach requires $O\left(z \log_2(a)\right)$ qubits as opposed to $O(za)$ qubits for P-PQM. EP-PQM also requires fewer gates, reducing gate count from $O\left(rza\right)$ to $O\left(rz\log_2(a)\right)$. For five datasets, we demonstrate that training an ML classification model using EP-PQM requires 48% to 77% fewer qubits than P-PQM for datasets with $a>2$. EP-PQM reduces circuit depth in the range of 60% to 96%, depending on the dataset. The depth decreases further with a decomposed circuit, ranging between 94% and 99%. EP-PQM requires less space; thus, it can train on and classify larger datasets than previous PQM implementations on NISQ devices. Furthermore, reducing the number of gates speeds up the classification and reduces the noise associated with deep quantum circuits. Thus, EP-PQM brings us closer to scalable ML on a NISQ device.

Quantum hardware and quantum-inspired algorithms are becoming increasingly popular for combinatorial optimization. However, these algorithms may require careful hyperparameter tuning for each problem instance. We use a reinforcement learning agent in conjunction with a quantum-inspired algorithm to solve the Ising energy minimization problem, which is equivalent to the Maximum Cut problem. The agent controls the algorithm by tuning one of its parameters with the goal of improving recently seen solutions. We propose a new Rescaled Ranked Reward (R3) method that enables stable single-player version of self-play training that helps the agent to escape local optima. The training on any problem instance can be accelerated by applying transfer learning from an agent trained on randomly generated problems. Our approach allows sampling high-quality solutions to the Ising problem with high probability and outperforms both baseline heuristics and a black-box hyperparameter optimization approach.