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This research explores a novel approach in the realm of learning-based image registration, addressing the limitations inherent in weakly-supervised and unsupervised methods. Weakly-supervised techniques depend heavily on scarce labeled data, while unsupervised strategies rely on indirect measures of accuracy through image similarity. Notably, traditional supervised learning is not utilized due to the lack of precise deformation ground-truth in medical imaging. Our study introduces a unique training framework with On-the-Fly Guidance (OFG) to enhance existing models. This framework, during training, generates pseudo-ground truth a few steps ahead by refining the current deformation prediction with our custom optimizer. This pseudo-ground truth then serves to directly supervise the model in a supervised learning context. The process involves optimizing the predicted deformation with a limited number of steps, ensuring training efficiency and setting achievable goals for each training phase. OFG notably boosts the precision of existing image registration techniques while maintaining the speed of learning-based methods. We assessed our approach using various pseudo-ground truth generation strategies, including predictions and optimized outputs from established registration models. Our experiments spanned three benchmark datasets and three cutting-edge models, with OFG demonstrating significant and consistent enhancements, surpassing previous state-of-the-arts in the field. OFG offers an easily integrable plug-and-play solution to enhance the training effectiveness of learning-based image registration models. Code at //github.com/miraclefactory/on-the-fly-guidance.

We present VideoPoet, a language model capable of synthesizing high-quality video, with matching audio, from a large variety of conditioning signals. VideoPoet employs a decoder-only transformer architecture that processes multimodal inputs -- including images, videos, text, and audio. The training protocol follows that of Large Language Models (LLMs), consisting of two stages: pretraining and task-specific adaptation. During pretraining, VideoPoet incorporates a mixture of multimodal generative objectives within an autoregressive Transformer framework. The pretrained LLM serves as a foundation that can be adapted for a range of video generation tasks. We present empirical results demonstrating the model's state-of-the-art capabilities in zero-shot video generation, specifically highlighting VideoPoet's ability to generate high-fidelity motions. Project page: //sites.research.google/videopoet/

We present DiffPortrait3D, a conditional diffusion model that is capable of synthesizing 3D-consistent photo-realistic novel views from as few as a single in-the-wild portrait. Specifically, given a single RGB input, we aim to synthesize plausible but consistent facial details rendered from novel camera views with retained both identity and facial expression. In lieu of time-consuming optimization and fine-tuning, our zero-shot method generalizes well to arbitrary face portraits with unposed camera views, extreme facial expressions, and diverse artistic depictions. At its core, we leverage the generative prior of 2D diffusion models pre-trained on large-scale image datasets as our rendering backbone, while the denoising is guided with disentangled attentive control of appearance and camera pose. To achieve this, we first inject the appearance context from the reference image into the self-attention layers of the frozen UNets. The rendering view is then manipulated with a novel conditional control module that interprets the camera pose by watching a condition image of a crossed subject from the same view. Furthermore, we insert a trainable cross-view attention module to enhance view consistency, which is further strengthened with a novel 3D-aware noise generation process during inference. We demonstrate state-of-the-art results both qualitatively and quantitatively on our challenging in-the-wild and multi-view benchmarks.

Conventional audio-visual approaches for active speaker detection (ASD) typically rely on visually pre-extracted face tracks and the corresponding single-channel audio to find the speaker in a video. Therefore, they tend to fail every time the face of the speaker is not visible. We demonstrate that a simple audio convolutional recurrent neural network (CRNN) trained with spatial input features extracted from multichannel audio can perform simultaneous horizontal active speaker detection and localization (ASDL), independently of the visual modality. To address the time and cost of generating ground truth labels to train such a system, we propose a new self-supervised training pipeline that embraces a ``student-teacher'' learning approach. A conventional pre-trained active speaker detector is adopted as a ``teacher'' network to provide the position of the speakers as pseudo-labels. The multichannel audio ``student'' network is trained to generate the same results. At inference, the student network can generalize and locate also the occluded speakers that the teacher network is not able to detect visually, yielding considerable improvements in recall rate. Experiments on the TragicTalkers dataset show that an audio network trained with the proposed self-supervised learning approach can exceed the performance of the typical audio-visual methods and produce results competitive with the costly conventional supervised training. We demonstrate that improvements can be achieved when minimal manual supervision is introduced in the learning pipeline. Further gains may be sought with larger training sets and integrating vision with the multichannel audio system.

We propose a two-stage estimation procedure for a copula-based model with semi-competing risks data, where the non-terminal event is subject to dependent censoring by the terminal event, and both events are subject to independent censoring. Under a copula-based model, the marginal survival functions of individual event times are specified by semiparametric transformation models, and the dependence between the bivariate event times is specified by a parametric copula function. For the estimation procedure, in the first stage, the parameters associated with the marginal of the terminal event are estimated only using the corresponding observed outcomes, and in the second stage, the marginal parameters for the non-terminal event time and the copula parameter are estimated via maximizing a pseudo-likelihood function based on the joint distribution of the bivariate event times. We derived the asymptotic properties of the proposed estimator and provided an analytic variance estimator for inference. Through simulation studies, we showed that our approach leads to consistent estimates with less computational cost and more robustness compared to the one-stage procedure developed in Chen (2012), where all parameters were estimated simultaneously. In addition, our approach demonstrates more desirable finite-sample performances over another existing two-stage estimation method proposed in Zhu et al. (2021).

In recent years, the deployment of large-scale pre-trained models in audio-visual downstream tasks has yielded remarkable outcomes. However, these models, primarily trained on single-modality unconstrained datasets, still encounter challenges in feature extraction for multi-modal tasks, leading to suboptimal performance. This limitation arises due to the introduction of irrelevant modality-specific information during encoding, which adversely affects the performance of downstream tasks. To address this challenge, this paper proposes a novel Dual-Guided Spatial-Channel-Temporal (DG-SCT) attention mechanism. This mechanism leverages audio and visual modalities as soft prompts to dynamically adjust the parameters of pre-trained models based on the current multi-modal input features. Specifically, the DG-SCT module incorporates trainable cross-modal interaction layers into pre-trained audio-visual encoders, allowing adaptive extraction of crucial information from the current modality across spatial, channel, and temporal dimensions, while preserving the frozen parameters of large-scale pre-trained models. Experimental evaluations demonstrate that our proposed model achieves state-of-the-art results across multiple downstream tasks, including AVE, AVVP, AVS, and AVQA. Furthermore, our model exhibits promising performance in challenging few-shot and zero-shot scenarios. The source code and pre-trained models are available at //github.com/haoyi-duan/DG-SCT.

Medical image segmentation modeling is a high-stakes task where understanding of uncertainty is crucial for addressing visual ambiguity. Prior work has developed segmentation models utilizing probabilistic or generative mechanisms to infer uncertainty from labels where annotators draw a singular boundary. However, as these annotations cannot represent an individual annotator's uncertainty, models trained on them produce uncertainty maps that are difficult to interpret. We propose a novel segmentation representation, Confidence Contours, which uses high- and low-confidence ``contours'' to capture uncertainty directly, and develop a novel annotation system for collecting contours. We conduct an evaluation on the Lung Image Dataset Consortium (LIDC) and a synthetic dataset. From an annotation study with 30 participants, results show that Confidence Contours provide high representative capacity without considerably higher annotator effort. We also find that general-purpose segmentation models can learn Confidence Contours at the same performance level as standard singular annotations. Finally, from interviews with 5 medical experts, we find that Confidence Contour maps are more interpretable than Bayesian maps due to representation of structural uncertainty.

We present a novel framework for generating photorealistic 3D human head and subsequently manipulating and reposing them with remarkable flexibility. The proposed approach leverages an implicit function representation of 3D human heads, employing 3D Gaussians anchored on a parametric face model. To enhance representational capabilities and encode spatial information, we embed a lightweight tri-plane payload within each Gaussian rather than directly storing color and opacity. Additionally, we parameterize the Gaussians in a 2D UV space via a 3DMM, enabling effective utilization of the diffusion model for 3D head avatar generation. Our method facilitates the creation of diverse and realistic 3D human heads with fine-grained editing over facial features and expressions. Extensive experiments demonstrate the effectiveness of our method.

Recent advancements in deep neural networks for graph-structured data have led to state-of-the-art performance on recommender system benchmarks. However, making these methods practical and scalable to web-scale recommendation tasks with billions of items and hundreds of millions of users remains a challenge. Here we describe a large-scale deep recommendation engine that we developed and deployed at Pinterest. We develop a data-efficient Graph Convolutional Network (GCN) algorithm PinSage, which combines efficient random walks and graph convolutions to generate embeddings of nodes (i.e., items) that incorporate both graph structure as well as node feature information. Compared to prior GCN approaches, we develop a novel method based on highly efficient random walks to structure the convolutions and design a novel training strategy that relies on harder-and-harder training examples to improve robustness and convergence of the model. We also develop an efficient MapReduce model inference algorithm to generate embeddings using a trained model. We deploy PinSage at Pinterest and train it on 7.5 billion examples on a graph with 3 billion nodes representing pins and boards, and 18 billion edges. According to offline metrics, user studies and A/B tests, PinSage generates higher-quality recommendations than comparable deep learning and graph-based alternatives. To our knowledge, this is the largest application of deep graph embeddings to date and paves the way for a new generation of web-scale recommender systems based on graph convolutional architectures.

High spectral dimensionality and the shortage of annotations make hyperspectral image (HSI) classification a challenging problem. Recent studies suggest that convolutional neural networks can learn discriminative spatial features, which play a paramount role in HSI interpretation. However, most of these methods ignore the distinctive spectral-spatial characteristic of hyperspectral data. In addition, a large amount of unlabeled data remains an unexploited gold mine for efficient data use. Therefore, we proposed an integration of generative adversarial networks (GANs) and probabilistic graphical models for HSI classification. Specifically, we used a spectral-spatial generator and a discriminator to identify land cover categories of hyperspectral cubes. Moreover, to take advantage of a large amount of unlabeled data, we adopted a conditional random field to refine the preliminary classification results generated by GANs. Experimental results obtained using two commonly studied datasets demonstrate that the proposed framework achieved encouraging classification accuracy using a small number of data for training.