Generalizability and transportability methods have been proposed to address the external validity bias of randomized clinical trials that results from differences in the distribution of treatment effect modifiers between trial and target populations. However, such studies present many challenges. We review and summarize state-of-the-art methodological considerations. We additionally provide investigators with a step-by-step guide to address these challenges, illustrated through a published case study. When conducted with rigor, such studies may play an integral role in regulatory decisions by providing key real-world evidence.
相關內容
Modern code review is a critical and indispensable practice in a pull-request development paradigm that prevails in Open Source Software (OSS) development. Finding a suitable reviewer in projects with massive participants thus becomes an increasingly challenging task. Many reviewer recommendation approaches (recommenders) have been developed to support this task which apply a similar strategy, i.e. modeling the review history first then followed by predicting/recommending a reviewer based on the model. Apparently, the better the model reflects the reality in review history, the higher recommender's performance we may expect. However, one typical scenario in a pull-request development paradigm, i.e. one Pull-Request (PR) (such as a revision or addition submitted by a contributor) may have multiple reviewers and they may impact each other through publicly posted comments, has not been modeled well in existing recommenders. We adopted the hypergraph technique to model this high-order relationship (i.e. one PR with multiple reviewers herein) and developed a new recommender, namely HGRec, which is evaluated by 12 OSS projects with more than 87K PRs, 680K comments in terms of accuracy and recommendation distribution. The results indicate that HGRec outperforms the state-of-the-art recommenders on recommendation accuracy. Besides, among the top three accurate recommenders, HGRec is more likely to recommend a diversity of reviewers, which can help to relieve the core reviewers' workload congestion issue. Moreover, since HGRec is based on hypergraph, which is a natural and interpretable representation to model review history, it is easy to accommodate more types of entities and realistic relationships in modern code review scenarios. As the first attempt, this study reveals the potentials of hypergraph on advancing the pragmatic solutions for code reviewer recommendation.
The stochastic nature of iterative optimization heuristics leads to inherently noisy performance measurements. Since these measurements are often gathered once and then used repeatedly, the number of collected samples will have a significant impact on the reliability of algorithm comparisons. We show that care should be taken when making decisions based on limited data. Particularly, we show that the number of runs used in many benchmarking studies, e.g., the default value of 15 suggested by the COCO environment, can be insufficient to reliably rank algorithms on well-known numerical optimization benchmarks. Additionally, methods for automated algorithm configuration are sensitive to insufficient sample sizes. This may result in the configurator choosing a `lucky' but poor-performing configuration despite exploring better ones. We show that relying on mean performance values, as many configurators do, can require a large number of runs to provide accurate comparisons between the considered configurations. Common statistical tests can greatly improve the situation in most cases but not always. We show examples of performance losses of more than 20%, even when using statistical races to dynamically adjust the number of runs, as done by irace. Our results underline the importance of appropriately considering the statistical distribution of performance values.
In recent years, the field of explainable AI (XAI) has produced a vast collection of algorithms, providing a useful toolbox for researchers and practitioners to build XAI applications. With the rich application opportunities, explainability is believed to have moved beyond a demand by data scientists or researchers to comprehend the models they develop, to an essential requirement for people to trust and adopt AI deployed in numerous domains. However, explainability is an inherently human-centric property and the field is starting to embrace human-centered approaches. Human-computer interaction (HCI) research and user experience (UX) design in this area are becoming increasingly important. In this chapter, we begin with a high-level overview of the technical landscape of XAI algorithms, then selectively survey our own and other recent HCI works that take human-centered approaches to design, evaluate, and provide conceptual and methodological tools for XAI. We ask the question "what are human-centered approaches doing for XAI" and highlight three roles that they play in shaping XAI technologies by helping navigate, assess and expand the XAI toolbox: to drive technical choices by users' explainability needs, to uncover pitfalls of existing XAI methods and inform new methods, and to provide conceptual frameworks for human-compatible XAI.
Obtaining a dynamic population distribution is key to many decision-making processes such as urban planning, disaster management and most importantly helping the government to better allocate socio-technical supply. For the aspiration of these objectives, good population data is essential. The traditional method of collecting population data through the census is expensive and tedious. In recent years, machine learning methods have been developed to estimate the population distribution. Most of the methods use data sets that are either developed on a small scale or not publicly available yet. Thus, the development and evaluation of the new methods become challenging. We fill this gap by providing a comprehensive data set for population estimation in 98 European cities. The data set comprises digital elevation model, local climate zone, land use classifications, nighttime lights in combination with multi-spectral Sentinel-2 imagery, and data from the Open Street Map initiative. We anticipate that it would be a valuable addition to the research community for the development of sophisticated machine learning-based approaches in the field of population estimation.
Images can convey rich semantics and induce various emotions in viewers. Recently, with the rapid advancement of emotional intelligence and the explosive growth of visual data, extensive research efforts have been dedicated to affective image content analysis (AICA). In this survey, we will comprehensively review the development of AICA in the recent two decades, especially focusing on the state-of-the-art methods with respect to three main challenges -- the affective gap, perception subjectivity, and label noise and absence. We begin with an introduction to the key emotion representation models that have been widely employed in AICA and description of available datasets for performing evaluation with quantitative comparison of label noise and dataset bias. We then summarize and compare the representative approaches on (1) emotion feature extraction, including both handcrafted and deep features, (2) learning methods on dominant emotion recognition, personalized emotion prediction, emotion distribution learning, and learning from noisy data or few labels, and (3) AICA based applications. Finally, we discuss some challenges and promising research directions in the future, such as image content and context understanding, group emotion clustering, and viewer-image interaction.
Deep Learning has implemented a wide range of applications and has become increasingly popular in recent years. The goal of multimodal deep learning is to create models that can process and link information using various modalities. Despite the extensive development made for unimodal learning, it still cannot cover all the aspects of human learning. Multimodal learning helps to understand and analyze better when various senses are engaged in the processing of information. This paper focuses on multiple types of modalities, i.e., image, video, text, audio, body gestures, facial expressions, and physiological signals. Detailed analysis of past and current baseline approaches and an in-depth study of recent advancements in multimodal deep learning applications has been provided. A fine-grained taxonomy of various multimodal deep learning applications is proposed, elaborating on different applications in more depth. Architectures and datasets used in these applications are also discussed, along with their evaluation metrics. Last, main issues are highlighted separately for each domain along with their possible future research directions.
Domain generalization (DG), i.e., out-of-distribution generalization, has attracted increased interests in recent years. Domain generalization deals with a challenging setting where one or several different but related domain(s) are given, and the goal is to learn a model that can generalize to an unseen test domain. For years, great progress has been achieved. This paper presents the first review for recent advances in domain generalization. First, we provide a formal definition of domain generalization and discuss several related fields. Next, we thoroughly review the theories related to domain generalization and carefully analyze the theory behind generalization. Then, we categorize recent algorithms into three classes and present them in detail: data manipulation, representation learning, and learning strategy, each of which contains several popular algorithms. Third, we introduce the commonly used datasets and applications. Finally, we summarize existing literature and present some potential research topics for the future.
Current deep learning research is dominated by benchmark evaluation. A method is regarded as favorable if it empirically performs well on the dedicated test set. This mentality is seamlessly reflected in the resurfacing area of continual learning, where consecutively arriving sets of benchmark data are investigated. The core challenge is framed as protecting previously acquired representations from being catastrophically forgotten due to the iterative parameter updates. However, comparison of individual methods is nevertheless treated in isolation from real world application and typically judged by monitoring accumulated test set performance. The closed world assumption remains predominant. It is assumed that during deployment a model is guaranteed to encounter data that stems from the same distribution as used for training. This poses a massive challenge as neural networks are well known to provide overconfident false predictions on unknown instances and break down in the face of corrupted data. In this work we argue that notable lessons from open set recognition, the identification of statistically deviating data outside of the observed dataset, and the adjacent field of active learning, where data is incrementally queried such that the expected performance gain is maximized, are frequently overlooked in the deep learning era. Based on these forgotten lessons, we propose a consolidated view to bridge continual learning, active learning and open set recognition in deep neural networks. Our results show that this not only benefits each individual paradigm, but highlights the natural synergies in a common framework. We empirically demonstrate improvements when alleviating catastrophic forgetting, querying data in active learning, selecting task orders, while exhibiting robust open world application where previously proposed methods fail.
Since deep neural networks were developed, they have made huge contributions to everyday lives. Machine learning provides more rational advice than humans are capable of in almost every aspect of daily life. However, despite this achievement, the design and training of neural networks are still challenging and unpredictable procedures. To lower the technical thresholds for common users, automated hyper-parameter optimization (HPO) has become a popular topic in both academic and industrial areas. This paper provides a review of the most essential topics on HPO. The first section introduces the key hyper-parameters related to model training and structure, and discusses their importance and methods to define the value range. Then, the research focuses on major optimization algorithms and their applicability, covering their efficiency and accuracy especially for deep learning networks. This study next reviews major services and toolkits for HPO, comparing their support for state-of-the-art searching algorithms, feasibility with major deep learning frameworks, and extensibility for new modules designed by users. The paper concludes with problems that exist when HPO is applied to deep learning, a comparison between optimization algorithms, and prominent approaches for model evaluation with limited computational resources.
Deep learning has become the most widely used approach for cardiac image segmentation in recent years. In this paper, we provide a review of over 100 cardiac image segmentation papers using deep learning, which covers common imaging modalities including magnetic resonance imaging (MRI), computed tomography (CT), and ultrasound (US) and major anatomical structures of interest (ventricles, atria and vessels). In addition, a summary of publicly available cardiac image datasets and code repositories are included to provide a base for encouraging reproducible research. Finally, we discuss the challenges and limitations with current deep learning-based approaches (scarcity of labels, model generalizability across different domains, interpretability) and suggest potential directions for future research.
小貼士
登錄享
注冊地址： 北京市海淀區羊坊店路18號2幢3層301-191