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Nominal assortativity (or discrete assortativity) is widely used to characterize group mixing patterns and homophily in networks, enabling researchers to analyze how groups interact with one another. Here we demonstrate that the measure presents severe shortcomings when applied to networks with unequal group sizes and asymmetric mixing. We characterize these shortcomings analytically and use synthetic and empirical networks to show that nominal assortativity fails to account for group imbalance and asymmetric group interactions, thereby producing an inaccurate characterization of mixing patterns. We propose adjusted nominal assortativity and show that this adjustment recovers the expected assortativity in networks with various level of mixing. Furthermore, we propose an analytical method to assess asymmetric mixing by estimating the tendency of inter- and intra-group connectivities. Finally, we discuss how this approach enables uncovering hidden mixing patterns in real-world networks.

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Agent-based models are widely used to predict infectious disease spread. For these predictions, one needs to understand how each input parameter affects the result. Here, some parameters may affect the sensitivities of others, requiring the analysis of higher order coefficients through e.g. Sobol sensitivity analysis. The geographical structures of real-world regions are distinct in that they are difficult to reduce to single parameter values, making a unified sensitivity analysis intractable. Yet analyzing the importance of geographical structure on the sensitivity of other input parameters is important because a strong effect would justify the use of models with real-world geographical representations, as opposed to stylized ones. Here we perform a grouped Sobol's sensitivity analysis on COVID-19 spread simulations across a set of three diverse real-world geographical representations. We study the differences in both results and the sensitivity of non-geographical parameters across these geographies. By comparing Sobol indices of parameters across geographies, we find evidence that infection rate could have more sensitivity in regions where the population is segregated, while parameters like recovery period of mild cases are more sensitive in regions with mixed populations. We also show how geographical structure affects parameter sensitivity changes over time.

Spiking neural network is a kind of neuromorphic computing that is believed to improve the level of intelligence and provide advantages for quantum computing. In this work, we address this issue by designing an optical spiking neural network and find that it can be used to accelerate the speed of computation, especially on combinatorial optimization problems. Here the spiking neural network is constructed by the antisymmetrically coupled degenerate optical parametric oscillator pulses and dissipative pulses. A nonlinear transfer function is chosen to mitigate amplitude inhomogeneities and destabilize the resulting local minima according to the dynamical behavior of spiking neurons. It is numerically shown that the spiking neural network-coherent Ising machines have excellent performance on combinatorial optimization problems, which is expected to offer new applications for neural computing and optical computing.

A new mechanical model on noncircular shallow tunnelling considering initial stress field is proposed in this paper by constraining far-field ground surface to eliminate displacement singularity at infinity, and the originally unbalanced tunnel excavation problem in existing solutions is turned to an equilibrium one of mixed boundaries. By applying analytic continuation, the mixed boundaries are transformed to a homogenerous Riemann-Hilbert problem, which is subsequently solved via an efficient and accurate iterative method with boundary conditions of static equilibrium, displacement single-valuedness, and traction along tunnel periphery. The Lanczos filtering technique is used in the final stress and displacement solution to reduce the Gibbs phenomena caused by the constrained far-field ground surface for more accurte results. Several numerical cases are conducted to intensively verify the proposed solution by examining boundary conditions and comparing with existing solutions, and all the results are in good agreements. Then more numerical cases are conducted to investigate the stress and deformation distribution along ground surface and tunnel periphery, and several engineering advices are given. Further discussions on the defects of the proposed solution are also conducted for objectivity.

High-dimensional central limit theorems have been intensively studied with most focus being on the case where the data is sub-Gaussian or sub-exponential. However, heavier tails are omnipresent in practice. In this article, we study the critical growth rates of dimension $d$ below which Gaussian approximations are asymptotically valid but beyond which they are not. We are particularly interested in how these thresholds depend on the number of moments $m$ that the observations possess. For every $m\in(2,\infty)$, we construct i.i.d. random vectors $\textbf{X}_1,...,\textbf{X}_n$ in $\mathbb{R}^d$, the entries of which are independent and have a common distribution (independent of $n$ and $d$) with finite $m$th absolute moment, and such that the following holds: if there exists an $\varepsilon\in(0,\infty)$ such that $d/n^{m/2-1+\varepsilon}\not\to 0$, then the Gaussian approximation error (GAE) satisfies $$ \limsup_{n\to\infty}\sup_{t\in\mathbb{R}}\left[\mathbb{P}\left(\max_{1\leq j\leq d}\frac{1}{\sqrt{n}}\sum_{i=1}^n\textbf{X}_{ij}\leq t\right)-\mathbb{P}\left(\max_{1\leq j\leq d}\textbf{Z}_j\leq t\right)\right]=1,$$ where $\textbf{Z} \sim \mathsf{N}_d(\textbf{0}_d,\mathbf{I}_d)$. On the other hand, a result in Chernozhukov et al. (2023a) implies that the left-hand side above is zero if just $d/n^{m/2-1-\varepsilon}\to 0$ for some $\varepsilon\in(0,\infty)$. In this sense, there is a moment-dependent phase transition at the threshold $d=n^{m/2-1}$ above which the limiting GAE jumps from zero to one.

Physics-informed neural networks have emerged as a coherent framework for building predictive models that combine statistical patterns with domain knowledge. The underlying notion is to enrich the optimization loss function with known relationships to constrain the space of possible solutions. Hydrodynamic simulations are a core constituent of modern cosmology, while the required computations are both expensive and time-consuming. At the same time, the comparatively fast simulation of dark matter requires fewer resources, which has led to the emergence of machine learning algorithms for baryon inpainting as an active area of research; here, recreating the scatter found in hydrodynamic simulations is an ongoing challenge. This paper presents the first application of physics-informed neural networks to baryon inpainting by combining advances in neural network architectures with physical constraints, injecting theory on baryon conversion efficiency into the model loss function. We also introduce a punitive prediction comparison based on the Kullback-Leibler divergence, which enforces scatter reproduction. By simultaneously extracting the complete set of baryonic properties for the Simba suite of cosmological simulations, our results demonstrate improved accuracy of baryonic predictions based on dark matter halo properties, successful recovery of the fundamental metallicity relation, and retrieve scatter that traces the target simulation's distribution.

This survey is concerned with the power of random information for approximation in the (deterministic) worst-case setting, with special emphasis on information that is obtained independently and identically distributed (iid) from a given distribution on a class of admissible information. We present a general result based on a weighted least squares method and derive consequences for special cases. Improvements are available if the information is "Gaussian" or if we consider iid function values for Sobolev spaces. We include open questions to guide future research on the power of random information in the context of information-based complexity.

The prevailing statistical approach to analyzing persistence diagrams is concerned with filtering out topological noise. In this paper, we adopt a different viewpoint and aim at estimating the actual distribution of a random persistence diagram, which captures both topological signal and noise. To that effect, Chazel and Divol (2019) proved that, under general conditions, the expected value of a random persistence diagram is a measure admitting a Lebesgue density, called the persistence intensity function. In this paper, we are concerned with estimating the persistence intensity function and a novel, normalized version of it -- called the persistence density function. We present a class of kernel-based estimators based on an i.i.d. sample of persistence diagrams and derive estimation rates in the supremum norm. As a direct corollary, we obtain uniform consistency rates for estimating linear representations of persistence diagrams, including Betti numbers and persistence surfaces. Interestingly, the persistence density function delivers stronger statistical guarantees.

Covariance matrices of random vectors contain information that is crucial for modelling. Certain structures and patterns of the covariances (or correlations) may be used to justify parametric models, e.g., autoregressive models. Until now, there have been only few approaches for testing such covariance structures systematically and in a unified way. In the present paper, we propose such a unified testing procedure, and we will exemplify the approach with a large variety of covariance structure models. This includes common structures such as diagonal matrices, Toeplitz matrices, and compound symmetry but also the more involved autoregressive matrices. We propose hypothesis tests for these structures, and we use bootstrap techniques for better small-sample approximation. The structures of the proposed tests invite for adaptations to other covariance patterns by choosing the hypothesis matrix appropriately. We prove their correctness for large sample sizes. The proposed methods require only weak assumptions. With the help of a simulation study, we assess the small sample properties of the tests. We also analyze a real data set to illustrate the application of the procedure.

We hypothesize that due to the greedy nature of learning in multi-modal deep neural networks, these models tend to rely on just one modality while under-fitting the other modalities. Such behavior is counter-intuitive and hurts the models' generalization, as we observe empirically. To estimate the model's dependence on each modality, we compute the gain on the accuracy when the model has access to it in addition to another modality. We refer to this gain as the conditional utilization rate. In the experiments, we consistently observe an imbalance in conditional utilization rates between modalities, across multiple tasks and architectures. Since conditional utilization rate cannot be computed efficiently during training, we introduce a proxy for it based on the pace at which the model learns from each modality, which we refer to as the conditional learning speed. We propose an algorithm to balance the conditional learning speeds between modalities during training and demonstrate that it indeed addresses the issue of greedy learning. The proposed algorithm improves the model's generalization on three datasets: Colored MNIST, Princeton ModelNet40, and NVIDIA Dynamic Hand Gesture.

Recent advances in 3D fully convolutional networks (FCN) have made it feasible to produce dense voxel-wise predictions of volumetric images. In this work, we show that a multi-class 3D FCN trained on manually labeled CT scans of several anatomical structures (ranging from the large organs to thin vessels) can achieve competitive segmentation results, while avoiding the need for handcrafting features or training class-specific models. To this end, we propose a two-stage, coarse-to-fine approach that will first use a 3D FCN to roughly define a candidate region, which will then be used as input to a second 3D FCN. This reduces the number of voxels the second FCN has to classify to ~10% and allows it to focus on more detailed segmentation of the organs and vessels. We utilize training and validation sets consisting of 331 clinical CT images and test our models on a completely unseen data collection acquired at a different hospital that includes 150 CT scans, targeting three anatomical organs (liver, spleen, and pancreas). In challenging organs such as the pancreas, our cascaded approach improves the mean Dice score from 68.5 to 82.2%, achieving the highest reported average score on this dataset. We compare with a 2D FCN method on a separate dataset of 240 CT scans with 18 classes and achieve a significantly higher performance in small organs and vessels. Furthermore, we explore fine-tuning our models to different datasets. Our experiments illustrate the promise and robustness of current 3D FCN based semantic segmentation of medical images, achieving state-of-the-art results. Our code and trained models are available for download: //github.com/holgerroth/3Dunet_abdomen_cascade.

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