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White Matter Hyperintensity (WMH) is an imaging feature related to various diseases such as dementia and stroke. Accurately segmenting WMH using computer technology is crucial for early disease diagnosis. However, this task remains challenging due to the small lesions with low contrast and high discontinuity in the images, which contain limited contextual and spatial information. To address this challenge, we propose a deep learning model called 3D Spatial Attention U-Net (3D SA-UNet) for automatic WMH segmentation using only Fluid Attenuation Inversion Recovery (FLAIR) scans. The 3D SA-UNet introduces a 3D Spatial Attention Module that highlights important lesion features, such as WMH, while suppressing unimportant regions. Additionally, to capture features at different scales, we extend the Atrous Spatial Pyramid Pooling (ASPP) module to a 3D version, enhancing the segmentation performance of the network. We evaluate our method on publicly available dataset and demonstrate the effectiveness of 3D spatial attention module and 3D ASPP in WMH segmentation. Through experimental results, it has been demonstrated that our proposed 3D SA-UNet model achieves higher accuracy compared to other state-of-the-art 3D convolutional neural networks.

相關內容

 3D是英文“Three Dimensions”的簡稱,中文是指三維、三個維度、三個坐標,即有長、有寬、有高,換句話說,就是立體的,是相對于只有長和寬的平面(2D)而言。

Single-Program-Multiple-Data (SPMD) parallelism has recently been adopted to train large deep neural networks (DNNs). Few studies have explored its applicability on heterogeneous clusters, to fully exploit available resources for large model learning. This paper presents \OurSystem, an automated system designed to expedite SPMD DNN training on heterogeneous clusters. \OurSystem jointly optimizes the tensor sharding strategy, sharding ratios across heterogeneous devices and the communication methods for tensor exchanges for optimized distributed training with SPMD parallelism. We novelly formulate model partitioning as a program synthesis problem, in which we generate a distributed program from scratch on a distributed instruction set that semantically resembles the program designed for a single device, and systematically explore the solution space with an A*-based search algorithm. We derive the optimal tensor sharding ratios by formulating it as a linear programming problem. Additionally, \OurSystem explores tensor communication optimization in a heterogeneous cluster and integrates it as part of the program synthesis process, for automatically choosing optimal collective communication primitives and applying sufficient factor broadcasting technique. Extensive experiments on representative workloads demonstrate that \OurSystem achieves up to 2.41x speed-up on heterogeneous clusters.

Uncertainty estimation in Neural Networks (NNs) is vital in improving reliability and confidence in predictions, particularly in safety-critical applications. Bayesian Neural Networks (BayNNs) with Dropout as an approximation offer a systematic approach to quantifying uncertainty, but they inherently suffer from high hardware overhead in terms of power, memory, and computation. Thus, the applicability of BayNNs to edge devices with limited resources or to high-performance applications is challenging. Some of the inherent costs of BayNNs can be reduced by accelerating them in hardware on a Computation-In-Memory (CIM) architecture with spintronic memories and binarizing their parameters. However, numerous stochastic units are required to implement conventional dropout-based BayNN. In this paper, we propose the Scale Dropout, a novel regularization technique for Binary Neural Networks (BNNs), and Monte Carlo-Scale Dropout (MC-Scale Dropout)-based BayNNs for efficient uncertainty estimation. Our approach requires only one stochastic unit for the entire model, irrespective of the model size, leading to a highly scalable Bayesian NN. Furthermore, we introduce a novel Spintronic memory-based CIM architecture for the proposed BayNN that achieves more than $100\times$ energy savings compared to the state-of-the-art. We validated our method to show up to a $1\%$ improvement in predictive performance and superior uncertainty estimates compared to related works.

Purpose: Body composition measurements from routine abdominal CT can yield personalized risk assessments for asymptomatic and diseased patients. In particular, attenuation and volume measures of muscle and fat are associated with important clinical outcomes, such as cardiovascular events, fractures, and death. This study evaluates the reliability of an Internal tool for the segmentation of muscle and fat (subcutaneous and visceral) as compared to the well-established public TotalSegmentator tool. Methods: We assessed the tools across 900 CT series from the publicly available SAROS dataset, focusing on muscle, subcutaneous fat, and visceral fat. The Dice score was employed to assess accuracy in subcutaneous fat and muscle segmentation. Due to the lack of ground truth segmentations for visceral fat, Cohen's Kappa was utilized to assess segmentation agreement between the tools. Results: Our Internal tool achieved a 3% higher Dice (83.8 vs. 80.8) for subcutaneous fat and a 5% improvement (87.6 vs. 83.2) for muscle segmentation respectively. A Wilcoxon signed-rank test revealed that our results were statistically different with p<0.01. For visceral fat, the Cohen's kappa score of 0.856 indicated near-perfect agreement between the two tools. Our internal tool also showed very strong correlations for muscle volume (R^2=0.99), muscle attenuation (R^2=0.93), and subcutaneous fat volume (R^2=0.99) with a moderate correlation for subcutaneous fat attenuation (R^2=0.45). Conclusion: Our findings indicated that our Internal tool outperformed TotalSegmentator in measuring subcutaneous fat and muscle. The high Cohen's Kappa score for visceral fat suggests a reliable level of agreement between the two tools. These results demonstrate the potential of our tool in advancing the accuracy of body composition analysis.

Diabetic Retinopathy (DR), an ocular complication of diabetes, is a leading cause of blindness worldwide. Traditionally, DR is monitored using Color Fundus Photography (CFP), a widespread 2-D imaging modality. However, DR classifications based on CFP have poor predictive power, resulting in suboptimal DR management. Optical Coherence Tomography Angiography (OCTA) is a recent 3-D imaging modality offering enhanced structural and functional information (blood flow) with a wider field of view. This paper investigates automatic DR severity assessment using 3-D OCTA. A straightforward solution to this task is a 3-D neural network classifier. However, 3-D architectures have numerous parameters and typically require many training samples. A lighter solution consists in using 2-D neural network classifiers processing 2-D en-face (or frontal) projections and/or 2-D cross-sectional slices. Such an approach mimics the way ophthalmologists analyze OCTA acquisitions: 1) en-face flow maps are often used to detect avascular zones and neovascularization, and 2) cross-sectional slices are commonly analyzed to detect macular edemas, for instance. However, arbitrary data reduction or selection might result in information loss. Two complementary strategies are thus proposed to optimally summarize OCTA volumes with 2-D images: 1) a parametric en-face projection optimized through deep learning and 2) a cross-sectional slice selection process controlled through gradient-based attribution. The full summarization and DR classification pipeline is trained from end to end. The automatic 2-D summary can be displayed in a viewer or printed in a report to support the decision. We show that the proposed 2-D summarization and classification pipeline outperforms direct 3-D classification with the advantage of improved interpretability.

Recently, the advent of large language models (LLMs) has revolutionized generative agents. Among them, Role-Playing Conversational Agents (RPCAs) attract considerable attention due to their ability to emotionally engage users. However, the absence of a comprehensive benchmark impedes progress in this field. To bridge this gap, we introduce CharacterEval, a Chinese benchmark for comprehensive RPCA assessment, complemented by a tailored high-quality dataset. The dataset comprises 1,785 multi-turn role-playing dialogues, encompassing 23,020 examples and featuring 77 characters derived from Chinese novels and scripts. It was carefully constructed, beginning with initial dialogue extraction via GPT-4, followed by rigorous human-led quality control, and enhanced with in-depth character profiles sourced from Baidu Baike. CharacterEval employs a multifaceted evaluation approach, encompassing thirteen targeted metrics on four dimensions. Comprehensive experiments on CharacterEval demonstrate that Chinese LLMs exhibit more promising capabilities than GPT-4 in Chinese role-playing conversation. Source code, data source and reward model will be publicly accessible at //github.com/morecry/CharacterEval.

The Spiking Neural Network (SNN) is a biologically inspired neural network infrastructure that has recently garnered significant attention. It utilizes binary spike activations to transmit information, thereby replacing multiplications with additions and resulting in high energy efficiency. However, training an SNN directly poses a challenge due to the undefined gradient of the firing spike process. Although prior works have employed various surrogate gradient training methods that use an alternative function to replace the firing process during back-propagation, these approaches ignore an intrinsic problem: gradient vanishing. To address this issue, we propose a shortcut back-propagation method in our paper, which advocates for transmitting the gradient directly from the loss to the shallow layers. This enables us to present the gradient to the shallow layers directly, thereby significantly mitigating the gradient vanishing problem. Additionally, this method does not introduce any burden during the inference phase. To strike a balance between final accuracy and ease of training, we also propose an evolutionary training framework and implement it by inducing a balance coefficient that dynamically changes with the training epoch, which further improves the network's performance. Extensive experiments conducted over static and dynamic datasets using several popular network structures reveal that our method consistently outperforms state-of-the-art methods.

Large Language Models (LLMs) are regularly being used to label data across many domains and for myriad tasks. By simply asking the LLM for an answer, or ``prompting,'' practitioners are able to use LLMs to quickly get a response for an arbitrary task. This prompting is done through a series of decisions by the practitioner, from simple wording of the prompt, to requesting the output in a certain data format, to jailbreaking in the case of prompts that address more sensitive topics. In this work, we ask: do variations in the way a prompt is constructed change the ultimate decision of the LLM? We answer this using a series of prompt variations across a variety of text classification tasks. We find that even the smallest of perturbations, such as adding a space at the end of a prompt, can cause the LLM to change its answer. Further, we find that requesting responses in XML and commonly used jailbreaks can have cataclysmic effects on the data labeled by LLMs.

Recently, a new paradigm, meta learning, has been widely applied to Deep Learning Recommendation Models (DLRM) and significantly improves statistical performance, especially in cold-start scenarios. However, the existing systems are not tailored for meta learning based DLRM models and have critical problems regarding efficiency in distributed training in the GPU cluster. It is because the conventional deep learning pipeline is not optimized for two task-specific datasets and two update loops in meta learning. This paper provides a high-performance framework for large-scale training for Optimization-based Meta DLRM models over the \textbf{G}PU cluster, namely \textbf{G}-Meta. Firstly, G-Meta utilizes both data parallelism and model parallelism with careful orchestration regarding computation and communication efficiency, to enable high-speed distributed training. Secondly, it proposes a Meta-IO pipeline for efficient data ingestion to alleviate the I/O bottleneck. Various experimental results show that G-Meta achieves notable training speed without loss of statistical performance. Since early 2022, G-Meta has been deployed in Alipay's core advertising and recommender system, shrinking the continuous delivery of models by four times. It also obtains 6.48\% improvement in Conversion Rate (CVR) and 1.06\% increase in CPM (Cost Per Mille) in Alipay's homepage display advertising, with the benefit of larger training samples and tasks.

Despite the potential of diffusion models in speech enhancement, their deployment in Acoustic Echo Cancellation (AEC) has been restricted. In this paper, we propose DI-AEC, pioneering a diffusion-based stochastic regeneration approach dedicated to AEC. Further, we propose FADI-AEC, fast score-based diffusion AEC framework to save computational demands, making it favorable for edge devices. It stands out by running the score model once per frame, achieving a significant surge in processing efficiency. Apart from that, we introduce a novel noise generation technique where far-end signals are utilized, incorporating both far-end and near-end signals to refine the score model's accuracy. We test our proposed method on the ICASSP2023 Microsoft deep echo cancellation challenge evaluation dataset, where our method outperforms some of the end-to-end methods and other diffusion based echo cancellation methods.

In recent years, Face Image Quality Assessment (FIQA) has become an indispensable part of the face recognition system to guarantee the stability and reliability of recognition performance in an unconstrained scenario. For this purpose, the FIQA method should consider both the intrinsic property and the recognizability of the face image. Most previous works aim to estimate the sample-wise embedding uncertainty or pair-wise similarity as the quality score, which only considers the information from partial intra-class. However, these methods ignore the valuable information from the inter-class, which is for estimating to the recognizability of face image. In this work, we argue that a high-quality face image should be similar to its intra-class samples and dissimilar to its inter-class samples. Thus, we propose a novel unsupervised FIQA method that incorporates Similarity Distribution Distance for Face Image Quality Assessment (SDD-FIQA). Our method generates quality pseudo-labels by calculating the Wasserstein Distance (WD) between the intra-class similarity distributions and inter-class similarity distributions. With these quality pseudo-labels, we are capable of training a regression network for quality prediction. Extensive experiments on benchmark datasets demonstrate that the proposed SDD-FIQA surpasses the state-of-the-arts by an impressive margin. Meanwhile, our method shows good generalization across different recognition systems.

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