Recent advances in large language models have led to renewed interest in natural language processing in healthcare using the free text of clinical notes. One distinguishing characteristic of clinical notes is their long time span over multiple long documents. The unique structure of clinical notes creates a new design choice: when the context length for a language model predictor is limited, which part of clinical notes should we choose as the input? Existing studies either choose the inputs with domain knowledge or simply truncate them. We propose a framework to analyze the sections with high predictive power. Using MIMIC-III, we show that: 1) predictive power distribution is different between nursing notes and discharge notes and 2) combining different types of notes could improve performance when the context length is large. Our findings suggest that a carefully selected sampling function could enable more efficient information extraction from clinical notes.
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Multimodal medical data fusion has emerged as a transformative approach in smart healthcare, enabling a comprehensive understanding of patient health and personalized treatment plans. In this paper, a journey from data to information to knowledge to wisdom (DIKW) is explored through multimodal fusion for smart healthcare. We present a comprehensive review of multimodal medical data fusion focused on the integration of various data modalities. The review explores different approaches such as feature selection, rule-based systems, machine learning, deep learning, and natural language processing, for fusing and analyzing multimodal data. This paper also highlights the challenges associated with multimodal fusion in healthcare. By synthesizing the reviewed frameworks and theories, it proposes a generic framework for multimodal medical data fusion that aligns with the DIKW model. Moreover, it discusses future directions related to the four pillars of healthcare: Predictive, Preventive, Personalized, and Participatory approaches. The components of the comprehensive survey presented in this paper form the foundation for more successful implementation of multimodal fusion in smart healthcare. Our findings can guide researchers and practitioners in leveraging the power of multimodal fusion with the state-of-the-art approaches to revolutionize healthcare and improve patient outcomes.
An "adequate" test suite should effectively find all inconsistencies between a system's requirements/specifications and its implementation. Practitioners frequently use code coverage to approximate adequacy, while academics argue that mutation score may better approximate true (oracular) adequacy coverage. High code coverage is increasingly attainable even on large systems via automatic test generation, including fuzzing. In light of all of these options for measuring and improving testing effort, how should a QA engineer spend their time? We propose a new framework for reasoning about the extent, limits, and nature of a given testing effort based on an idea we call the oracle gap, or the difference between source code coverage and mutation score for a given software element. We conduct (1) a large-scale observational study of the oracle gap across popular Maven projects, (2) a study that varies testing and oracle quality across several of those projects and (3) a small-scale observational study of highly critical, well-tested code across comparable blockchain projects. We show that the oracle gap surfaces important information about the extent and quality of a test effort beyond either adequacy metric alone. In particular, it provides a way for practitioners to identify source files where it is likely a weak oracle tests important code.
Best Arm Identification (BAI) problems are progressively used for data-sensitive applications, such as designing adaptive clinical trials, tuning hyper-parameters, and conducting user studies to name a few. Motivated by the data privacy concerns invoked by these applications, we study the problem of BAI with fixed confidence under $\epsilon$-global Differential Privacy (DP). First, to quantify the cost of privacy, we derive a lower bound on the sample complexity of any $\delta$-correct BAI algorithm satisfying $\epsilon$-global DP. Our lower bound suggests the existence of two privacy regimes depending on the privacy budget $\epsilon$. In the high-privacy regime (small $\epsilon$), the hardness depends on a coupled effect of privacy and a novel information-theoretic quantity, called the Total Variation Characteristic Time. In the low-privacy regime (large $\epsilon$), the sample complexity lower bound reduces to the classical non-private lower bound. Second, we propose AdaP-TT, an $\epsilon$-global DP variant of the Top Two algorithm. AdaP-TT runs in arm-dependent adaptive episodes and adds Laplace noise to ensure a good privacy-utility trade-off. We derive an asymptotic upper bound on the sample complexity of AdaP-TT that matches with the lower bound up to multiplicative constants in the high-privacy regime. Finally, we provide an experimental analysis of AdaP-TT that validates our theoretical results.
AI has led to significant advancements in computer vision and image processing tasks, enabling a wide range of applications in real-life scenarios, from autonomous vehicles to medical imaging. Many of those applications require efficient object detection algorithms and complementary real-time, low latency hardware to perform inference of these algorithms. The YOLO family of models is considered the most efficient for object detection, having only a single model pass. Despite this, the complexity and size of YOLO models can be too computationally demanding for current edge-based platforms. To address this, we present SATAY: a Streaming Architecture Toolflow for Accelerating YOLO. This work tackles the challenges of deploying stateof-the-art object detection models onto FPGA devices for ultralow latency applications, enabling real-time, edge-based object detection. We employ a streaming architecture design for our YOLO accelerators, implementing the complete model on-chip in a deeply pipelined fashion. These accelerators are generated using an automated toolflow, and can target a range of suitable FPGA devices. We introduce novel hardware components to support the operations of YOLO models in a dataflow manner, and off-chip memory buffering to address the limited on-chip memory resources. Our toolflow is able to generate accelerator designs which demonstrate competitive performance and energy characteristics to GPU devices, and which outperform current state-of-the-art FPGA accelerators.
In the procedure of surface defects detection for large-aperture aspherical optical elements, it is of vital significance to adjust the optical axis of the element to be coaxial with the mechanical spin axis accurately. Therefore, a machine vision method for eccentric error correction is proposed in this paper. Focusing on the severe defocus blur of reference crosshair image caused by the imaging characteristic of the aspherical optical element, which may lead to the failure of correction, an Adaptive Enhancement Algorithm (AEA) is proposed to strengthen the crosshair image. AEA is consisted of existed Guided Filter Dark Channel Dehazing Algorithm (GFA) and proposed lightweight Multi-scale Densely Connected Network (MDC-Net). The enhancement effect of GFA is excellent but time-consuming, and the enhancement effect of MDC-Net is slightly inferior but strongly real-time. As AEA will be executed dozens of times during each correction procedure, its real-time performance is very important. Therefore, by setting the empirical threshold of definition evaluation function SMD2, GFA and MDC-Net are respectively applied to highly and slightly blurred crosshair images so as to ensure the enhancement effect while saving as much time as possible. AEA has certain robustness in time-consuming performance, which takes an average time of 0.2721s and 0.0963s to execute GFA and MDC-Net separately on ten 200pixels 200pixels Region of Interest (ROI) images with different degrees of blur. And the eccentricity error can be reduced to within 10um by our method.
The recent advances in deep-learning have led to the development of highly sophisticated systems with an unquenchable appetite for data. On the other hand, building good deep-learning models for low-resource languages remains a challenging task. This paper focuses on developing a Question Answering dataset for two such languages- Hindi and Marathi. Despite Hindi being the 3rd most spoken language worldwide, with 345 million speakers, and Marathi being the 11th most spoken language globally, with 83.2 million speakers, both languages face limited resources for building efficient Question Answering systems. To tackle the challenge of data scarcity, we have developed a novel approach for translating the SQuAD 2.0 dataset into Hindi and Marathi. We release the largest Question-Answering dataset available for these languages, with each dataset containing 28,000 samples. We evaluate the dataset on various architectures and release the best-performing models for both Hindi and Marathi, which will facilitate further research in these languages. Leveraging similarity tools, our method holds the potential to create datasets in diverse languages, thereby enhancing the understanding of natural language across varied linguistic contexts. Our fine-tuned models, code, and dataset will be made publicly available.
Connected automated vehicles have shown great potential to improve the efficiency of transportation systems in terms of passenger comfort, fuel economy, stability of driving behavior and mitigation of traffic congestions. Yet, to deploy these vehicles and leverage their benefits, the underlying algorithms must ensure their safe operation. In this paper, we address the safety of connected cruise control strategies for longitudinal car following using control barrier function (CBF) theory. In particular, we consider various safety measures such as minimum distance, time headway and time to conflict, and provide a formal analysis of these measures through the lens of CBFs. Additionally, motivated by how stability charts facilitate stable controller design, we derive safety charts for existing connected cruise controllers to identify safe choices of controller parameters. Finally, we combine the analysis of safety measures and the corresponding stability charts to synthesize safety-critical connected cruise controllers using CBFs. We verify our theoretical results by numerical simulations.
The rapid advancements in machine learning, graphics processing technologies and availability of medical imaging data has led to a rapid increase in use of machine learning models in the medical domain. This was exacerbated by the rapid advancements in convolutional neural network (CNN) based architectures, which were adopted by the medical imaging community to assist clinicians in disease diagnosis. Since the grand success of AlexNet in 2012, CNNs have been increasingly used in medical image analysis to improve the efficiency of human clinicians. In recent years, three-dimensional (3D) CNNs have been employed for analysis of medical images. In this paper, we trace the history of how the 3D CNN was developed from its machine learning roots, brief mathematical description of 3D CNN and the preprocessing steps required for medical images before feeding them to 3D CNNs. We review the significant research in the field of 3D medical imaging analysis using 3D CNNs (and its variants) in different medical areas such as classification, segmentation, detection, and localization. We conclude by discussing the challenges associated with the use of 3D CNNs in the medical imaging domain (and the use of deep learning models, in general) and possible future trends in the field.
Small data challenges have emerged in many learning problems, since the success of deep neural networks often relies on the availability of a huge amount of labeled data that is expensive to collect. To address it, many efforts have been made on training complex models with small data in an unsupervised and semi-supervised fashion. In this paper, we will review the recent progresses on these two major categories of methods. A wide spectrum of small data models will be categorized in a big picture, where we will show how they interplay with each other to motivate explorations of new ideas. We will review the criteria of learning the transformation equivariant, disentangled, self-supervised and semi-supervised representations, which underpin the foundations of recent developments. Many instantiations of unsupervised and semi-supervised generative models have been developed on the basis of these criteria, greatly expanding the territory of existing autoencoders, generative adversarial nets (GANs) and other deep networks by exploring the distribution of unlabeled data for more powerful representations. While we focus on the unsupervised and semi-supervised methods, we will also provide a broader review of other emerging topics, from unsupervised and semi-supervised domain adaptation to the fundamental roles of transformation equivariance and invariance in training a wide spectrum of deep networks. It is impossible for us to write an exclusive encyclopedia to include all related works. Instead, we aim at exploring the main ideas, principles and methods in this area to reveal where we are heading on the journey towards addressing the small data challenges in this big data era.
We propose a novel attention gate (AG) model for medical imaging that automatically learns to focus on target structures of varying shapes and sizes. Models trained with AGs implicitly learn to suppress irrelevant regions in an input image while highlighting salient features useful for a specific task. This enables us to eliminate the necessity of using explicit external tissue/organ localisation modules of cascaded convolutional neural networks (CNNs). AGs can be easily integrated into standard CNN architectures such as the U-Net model with minimal computational overhead while increasing the model sensitivity and prediction accuracy. The proposed Attention U-Net architecture is evaluated on two large CT abdominal datasets for multi-class image segmentation. Experimental results show that AGs consistently improve the prediction performance of U-Net across different datasets and training sizes while preserving computational efficiency. The code for the proposed architecture is publicly available.
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