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Recent advances in computer vision have shown promising results in image generation. Diffusion probabilistic models in particular have generated realistic images from textual input, as demonstrated by DALL-E 2, Imagen and Stable Diffusion. However, their use in medicine, where image data typically comprises three-dimensional volumes, has not been systematically evaluated. Synthetic images may play a crucial role in privacy preserving artificial intelligence and can also be used to augment small datasets. Here we show that diffusion probabilistic models can synthesize high quality medical imaging data, which we show for Magnetic Resonance Images (MRI) and Computed Tomography (CT) images. We provide quantitative measurements of their performance through a reader study with two medical experts who rated the quality of the synthesized images in three categories: Realistic image appearance, anatomical correctness and consistency between slices. Furthermore, we demonstrate that synthetic images can be used in a self-supervised pre-training and improve the performance of breast segmentation models when data is scarce (dice score 0.91 vs. 0.95 without vs. with synthetic data).

Current approaches to empathetic response generation typically encode the entire dialogue history directly and put the output into a decoder to generate friendly feedback. These methods focus on modelling contextual information but neglect capturing the direct intention of the speaker. We argue that the last utterance in the dialogue empirically conveys the intention of the speaker. Consequently, we propose a novel model named InferEM for empathetic response generation. We separately encode the last utterance and fuse it with the entire dialogue through multi-head attention based intention fusion module to capture the speaker's intention. Besides, we utilize previous utterances to predict the last utterance, which simulates human's psychology to guess what the interlocutor may speak in advance. To balance the optimizing rates of the utterance prediction and response generation, a multi-task learning strategy is designed for InferEM. Experimental results demonstrate the plausibility and validity of InferEM in improving empathetic expression.

Many classical fairy tales, fiction, and screenplays leverage dialogue to advance story plots and establish characters. We present the first study to explore whether machines can understand and generate dialogue in stories, which requires capturing traits of different characters and the relationships between them. To this end, we propose two new tasks including Masked Dialogue Generation and Dialogue Speaker Recognition, i.e., generating missing dialogue turns and predicting speakers for specified dialogue turns, respectively. We build a new dataset DialStory, which consists of 105k Chinese stories with a large amount of dialogue weaved into the plots to support the evaluation. We show the difficulty of the proposed tasks by testing existing models with automatic and manual evaluation on DialStory. Furthermore, we propose to learn explicit character representations to improve performance on these tasks. Extensive experiments and case studies show that our approach can generate more coherent and informative dialogue, and achieve higher speaker recognition accuracy than strong baselines.

The dominant multi-camera 3D detection paradigm is based on explicit 3D feature construction, which requires complicated indexing of local image-view features via 3D-to-2D projection. Other methods implicitly introduce geometric positional encoding and perform global attention (e.g., PETR) to build the relationship between image tokens and 3D objects. The 3D-to-2D perspective inconsistency and global attention lead to a weak correlation between foreground tokens and queries, resulting in slow convergence. We propose Focal-PETR with instance-guided supervision and spatial alignment module to adaptively focus object queries on discriminative foreground regions. Focal-PETR additionally introduces a down-sampling strategy to reduce the consumption of global attention. Due to the highly parallelized implementation and down-sampling strategy, our model, without depth supervision, achieves leading performance on the large-scale nuScenes benchmark and a superior speed of 30 FPS on a single RTX3090 GPU. Extensive experiments show that our method outperforms PETR while consuming 3x fewer training hours. The code will be made publicly available.

Human-centric perception plays a vital role in vision and graphics. But their data annotations are prohibitively expensive. Therefore, it is desirable to have a versatile pre-train model that serves as a foundation for data-efficient downstream tasks transfer. To this end, we propose the Human-Centric Multi-Modal Contrastive Learning framework HCMoCo that leverages the multi-modal nature of human data (e.g. RGB, depth, 2D keypoints) for effective representation learning. The objective comes with two main challenges: dense pre-train for multi-modality data, efficient usage of sparse human priors. To tackle the challenges, we design the novel Dense Intra-sample Contrastive Learning and Sparse Structure-aware Contrastive Learning targets by hierarchically learning a modal-invariant latent space featured with continuous and ordinal feature distribution and structure-aware semantic consistency. HCMoCo provides pre-train for different modalities by combining heterogeneous datasets, which allows efficient usage of existing task-specific human data. Extensive experiments on four downstream tasks of different modalities demonstrate the effectiveness of HCMoCo, especially under data-efficient settings (7.16% and 12% improvement on DensePose Estimation and Human Parsing). Moreover, we demonstrate the versatility of HCMoCo by exploring cross-modality supervision and missing-modality inference, validating its strong ability in cross-modal association and reasoning.

Human doctors with well-structured medical knowledge can diagnose a disease merely via a few conversations with patients about symptoms. In contrast, existing knowledge-grounded dialogue systems often require a large number of dialogue instances to learn as they fail to capture the correlations between different diseases and neglect the diagnostic experience shared among them. To address this issue, we propose a more natural and practical paradigm, i.e., low-resource medical dialogue generation, which can transfer the diagnostic experience from source diseases to target ones with a handful of data for adaptation. It is capitalized on a commonsense knowledge graph to characterize the prior disease-symptom relations. Besides, we develop a Graph-Evolving Meta-Learning (GEML) framework that learns to evolve the commonsense graph for reasoning disease-symptom correlations in a new disease, which effectively alleviates the needs of a large number of dialogues. More importantly, by dynamically evolving disease-symptom graphs, GEML also well addresses the real-world challenges that the disease-symptom correlations of each disease may vary or evolve along with more diagnostic cases. Extensive experiment results on the CMDD dataset and our newly-collected Chunyu dataset testify the superiority of our approach over state-of-the-art approaches. Besides, our GEML can generate an enriched dialogue-sensitive knowledge graph in an online manner, which could benefit other tasks grounded on knowledge graph.

Deep learning-based semi-supervised learning (SSL) algorithms have led to promising results in medical images segmentation and can alleviate doctors' expensive annotations by leveraging unlabeled data. However, most of the existing SSL algorithms in literature tend to regularize the model training by perturbing networks and/or data. Observing that multi/dual-task learning attends to various levels of information which have inherent prediction perturbation, we ask the question in this work: can we explicitly build task-level regularization rather than implicitly constructing networks- and/or data-level perturbation-and-transformation for SSL? To answer this question, we propose a novel dual-task-consistency semi-supervised framework for the first time. Concretely, we use a dual-task deep network that jointly predicts a pixel-wise segmentation map and a geometry-aware level set representation of the target. The level set representation is converted to an approximated segmentation map through a differentiable task transform layer. Simultaneously, we introduce a dual-task consistency regularization between the level set-derived segmentation maps and directly predicted segmentation maps for both labeled and unlabeled data. Extensive experiments on two public datasets show that our method can largely improve the performance by incorporating the unlabeled data. Meanwhile, our framework outperforms the state-of-the-art semi-supervised medical image segmentation methods. Code is available at: //github.com/Luoxd1996/DTC

Recent advances in maximizing mutual information (MI) between the source and target have demonstrated its effectiveness in text generation. However, previous works paid little attention to modeling the backward network of MI (i.e., dependency from the target to the source), which is crucial to the tightness of the variational information maximization lower bound. In this paper, we propose Adversarial Mutual Information (AMI): a text generation framework which is formed as a novel saddle point (min-max) optimization aiming to identify joint interactions between the source and target. Within this framework, the forward and backward networks are able to iteratively promote or demote each other's generated instances by comparing the real and synthetic data distributions. We also develop a latent noise sampling strategy that leverages random variations at the high-level semantic space to enhance the long term dependency in the generation process. Extensive experiments based on different text generation tasks demonstrate that the proposed AMI framework can significantly outperform several strong baselines, and we also show that AMI has potential to lead to a tighter lower bound of maximum mutual information for the variational information maximization problem.

Neural network models usually suffer from the challenge of incorporating commonsense knowledge into the open-domain dialogue systems. In this paper, we propose a novel knowledge-aware dialogue generation model (called TransDG), which transfers question representation and knowledge matching abilities from knowledge base question answering (KBQA) task to facilitate the utterance understanding and factual knowledge selection for dialogue generation. In addition, we propose a response guiding attention and a multi-step decoding strategy to steer our model to focus on relevant features for response generation. Experiments on two benchmark datasets demonstrate that our model has robust superiority over compared methods in generating informative and fluent dialogues. Our code is available at //github.com/siat-nlp/TransDG.

We propose a new method for event extraction (EE) task based on an imitation learning framework, specifically, inverse reinforcement learning (IRL) via generative adversarial network (GAN). The GAN estimates proper rewards according to the difference between the actions committed by the expert (or ground truth) and the agent among complicated states in the environment. EE task benefits from these dynamic rewards because instances and labels yield to various extents of difficulty and the gains are expected to be diverse -- e.g., an ambiguous but correctly detected trigger or argument should receive high gains -- while the traditional RL models usually neglect such differences and pay equal attention on all instances. Moreover, our experiments also demonstrate that the proposed framework outperforms state-of-the-art methods, without explicit feature engineering.