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The canonical technique for nonlinear modeling of spatial and other point-referenced data is known as kriging in the geostatistics literature, and by Gaussian Process (GP) regression in surrogate modeling and machine learning communities. There are many similarities shared between kriging and GPs, but also some important differences. One is that GPs impose a process on the data-generating mechanism that can be used to automate kernel/variogram inference, thus removing the human from the loop in a conventional semivariogram analysis. The GP framework also suggests a probabilistically valid means of scaling to handle a large corpus of training data, i.e., an alternative to so-called ordinary kriging. Finally, recent GP implementations are tailored to make the most of modern computing architectures such as multi-core workstations and multi-node supercomputers. Ultimately, we use this discussion as a springboard for an empirics-based advocacy of state-of-the-art GP technology in the geospatial modeling of a large corpus of borehole data involved in mining for gold and other minerals. Our out-of-sample validation exercise quantifies how GP methods (as implemented by open source libraries) can be both more economical (fewer human and compute resources), more accurate and offer better uncertainty quantification than kriging-based alternatives. Once in the GP framework, several possible extensions benefit from a fully generative modeling apparatus. In particular, we showcase a simple imputation scheme that copes with left-censoring of small measurements, which is a common feature in borehole assays.

The Associazione Medici Diabetologi (AMD) collects and manages one of the largest worldwide-available collections of diabetic patient records, also known as the AMD database. This paper presents the initial results of an ongoing project whose focus is the application of Artificial Intelligence and Machine Learning techniques for conceptualizing, cleaning, and analyzing such an important and valuable dataset, with the goal of providing predictive insights to better support diabetologists in their diagnostic and therapeutic choices.

The ability to learn new concepts continually is necessary in this ever-changing world. However, deep neural networks suffer from catastrophic forgetting when learning new categories. Many works have been proposed to alleviate this phenomenon, whereas most of them either fall into the stability-plasticity dilemma or take too much computation or storage overhead. Inspired by the gradient boosting algorithm to gradually fit the residuals between the target model and the previous ensemble model, we propose a novel two-stage learning paradigm FOSTER, empowering the model to learn new categories adaptively. Specifically, we first dynamically expand new modules to fit the residuals between the target and the output of the original model. Next, we remove redundant parameters and feature dimensions through an effective distillation strategy to maintain the single backbone model. We validate our method FOSTER on CIFAR-100 and ImageNet-100/1000 under different settings. Experimental results show that our method achieves state-of-the-art performance. Code is available at: //github.com/G-U-N/ECCV22-FOSTER.

Many fundamental problems affecting the care of critically ill patients lead to similar analytical challenges: physicians cannot easily estimate the effects of at-risk medical conditions or treatments because the causal effects of medical conditions and drugs are entangled. They also cannot easily perform studies: there are not enough high-quality data for high-dimensional observational causal inference, and RCTs often cannot ethically be conducted. However, mechanistic knowledge is available, including how drugs are absorbed into the body, and the combination of this knowledge with the limited data could potentially suffice -- if we knew how to combine them. In this work, we present a framework for interpretable estimation of causal effects for critically ill patients under exactly these complex conditions: interactions between drugs and observations over time, patient data sets that are not large, and mechanistic knowledge that can substitute for lack of data. We apply this framework to an extremely important problem affecting critically ill patients, namely the effect of seizures and other potentially harmful electrical events in the brain (called epileptiform activity -- EA) on outcomes. Given the high stakes involved and the high noise in the data, interpretability is critical for troubleshooting such complex problems. Interpretability of our matched groups allowed neurologists to perform chart reviews to verify the quality of our causal analysis. For instance, our work indicates that a patient who experiences a high level of seizure-like activity (75% high EA burden) and is untreated for a six-hour window, has, on average, a 16.7% increased chance of adverse outcomes such as severe brain damage, lifetime disability, or death. We find that patients with mild but long-lasting EA (average EA burden >= 50%) have their risk of an adverse outcome increased by 11.2%.

The remarkable success of deep learning has prompted interest in its application to medical diagnosis. Even tough state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of medical data, these models are hardly adopted in clinical workflows, mainly due to their lack of interpretability. The black-box-ness of deep learning models has raised the need for devising strategies to explain the decision process of these models, leading to the creation of the topic of eXplainable Artificial Intelligence (XAI). In this context, we provide a thorough survey of XAI applied to medical diagnosis, including visual, textual, and example-based explanation methods. Moreover, this work reviews the existing medical imaging datasets and the existing metrics for evaluating the quality of the explanations . Complementary to most existing surveys, we include a performance comparison among a set of report generation-based methods. Finally, the major challenges in applying XAI to medical imaging are also discussed.

Inspired by the human cognitive system, attention is a mechanism that imitates the human cognitive awareness about specific information, amplifying critical details to focus more on the essential aspects of data. Deep learning has employed attention to boost performance for many applications. Interestingly, the same attention design can suit processing different data modalities and can easily be incorporated into large networks. Furthermore, multiple complementary attention mechanisms can be incorporated in one network. Hence, attention techniques have become extremely attractive. However, the literature lacks a comprehensive survey specific to attention techniques to guide researchers in employing attention in their deep models. Note that, besides being demanding in terms of training data and computational resources, transformers only cover a single category in self-attention out of the many categories available. We fill this gap and provide an in-depth survey of 50 attention techniques categorizing them by their most prominent features. We initiate our discussion by introducing the fundamental concepts behind the success of attention mechanism. Next, we furnish some essentials such as the strengths and limitations of each attention category, describe their fundamental building blocks, basic formulations with primary usage, and applications specifically for computer vision. We also discuss the challenges and open questions related to attention mechanism in general. Finally, we recommend possible future research directions for deep attention.

Medical Visual Question Answering (VQA) is a combination of medical artificial intelligence and popular VQA challenges. Given a medical image and a clinically relevant question in natural language, the medical VQA system is expected to predict a plausible and convincing answer. Although the general-domain VQA has been extensively studied, the medical VQA still needs specific investigation and exploration due to its task features. In the first part of this survey, we cover and discuss the publicly available medical VQA datasets up to date about the data source, data quantity, and task feature. In the second part, we review the approaches used in medical VQA tasks. In the last part, we analyze some medical-specific challenges for the field and discuss future research directions.

Federated Learning (FL) is a decentralized machine-learning paradigm, in which a global server iteratively averages the model parameters of local users without accessing their data. User heterogeneity has imposed significant challenges to FL, which can incur drifted global models that are slow to converge. Knowledge Distillation has recently emerged to tackle this issue, by refining the server model using aggregated knowledge from heterogeneous users, other than directly averaging their model parameters. This approach, however, depends on a proxy dataset, making it impractical unless such a prerequisite is satisfied. Moreover, the ensemble knowledge is not fully utilized to guide local model learning, which may in turn affect the quality of the aggregated model. Inspired by the prior art, we propose a data-free knowledge distillation} approach to address heterogeneous FL, where the server learns a lightweight generator to ensemble user information in a data-free manner, which is then broadcasted to users, regulating local training using the learned knowledge as an inductive bias. Empirical studies powered by theoretical implications show that, our approach facilitates FL with better generalization performance using fewer communication rounds, compared with the state-of-the-art.

Transfer learning aims at improving the performance of target learners on target domains by transferring the knowledge contained in different but related source domains. In this way, the dependence on a large number of target domain data can be reduced for constructing target learners. Due to the wide application prospects, transfer learning has become a popular and promising area in machine learning. Although there are already some valuable and impressive surveys on transfer learning, these surveys introduce approaches in a relatively isolated way and lack the recent advances in transfer learning. As the rapid expansion of the transfer learning area, it is both necessary and challenging to comprehensively review the relevant studies. This survey attempts to connect and systematize the existing transfer learning researches, as well as to summarize and interpret the mechanisms and the strategies in a comprehensive way, which may help readers have a better understanding of the current research status and ideas. Different from previous surveys, this survey paper reviews over forty representative transfer learning approaches from the perspectives of data and model. The applications of transfer learning are also briefly introduced. In order to show the performance of different transfer learning models, twenty representative transfer learning models are used for experiments. The models are performed on three different datasets, i.e., Amazon Reviews, Reuters-21578, and Office-31. And the experimental results demonstrate the importance of selecting appropriate transfer learning models for different applications in practice.

Most existing works in visual question answering (VQA) are dedicated to improving the accuracy of predicted answers, while disregarding the explanations. We argue that the explanation for an answer is of the same or even more importance compared with the answer itself, since it makes the question and answering process more understandable and traceable. To this end, we propose a new task of VQA-E (VQA with Explanation), where the computational models are required to generate an explanation with the predicted answer. We first construct a new dataset, and then frame the VQA-E problem in a multi-task learning architecture. Our VQA-E dataset is automatically derived from the VQA v2 dataset by intelligently exploiting the available captions. We have conducted a user study to validate the quality of explanations synthesized by our method. We quantitatively show that the additional supervision from explanations can not only produce insightful textual sentences to justify the answers, but also improve the performance of answer prediction. Our model outperforms the state-of-the-art methods by a clear margin on the VQA v2 dataset.