Tuberculosis (TB) is still recognized as one of the leading causes of death worldwide. Recent advances in deep learning (DL) have shown to enhance radiologists' ability to interpret chest X-ray (CXR) images accurately and with fewer errors, leading to a better diagnosis of this disease. However, little work has been done to develop models capable of diagnosing TB that offer good performance while being efficient, fast and computationally inexpensive. In this work, we propose LightTBNet, a novel lightweight, fast and efficient deep convolutional network specially customized to detect TB from CXR images. Using a total of 800 frontal CXR images from two publicly available datasets, our solution yielded an accuracy, F1 and area under the ROC curve (AUC) of 0.906, 0.907 and 0.961, respectively, on an independent test subset. The proposed model demonstrates outstanding performance while delivering a rapid prediction, with minimal computational and memory requirements, making it highly suitable for deployment in handheld devices that can be used in low-resource areas with high TB prevalence. Code publicly available at //github.com/dani-capellan/LightTBNet.
The advent of large pre-trained language models in the domain of Code Synthesis has shown remarkable performance on various benchmarks, treating the problem of Code Generation in a fashion similar to Natural Language Generation, trained with a Language Modelling (LM) objective. In addition, the property of programming language code being precisely evaluable with respect to its semantics -- through the use of Unit Tests to check its functional correctness -- lends itself to using Reinforcement Learning (RL) as a further training paradigm. Previous work has shown that RL can be applied as such to improve models' coding capabilities; however, such RL-based methods rely on a reward signal based on defined Unit Tests, which are much harder to obtain compared to the huge crawled code datasets used in LM objectives. In this work, we present a novel approach to automatically obtain data consisting of function signatures and associated Unit Tests, suitable for RL training of Code Synthesis models. We also introduce a straightforward, simple yet effective Actor-Critic RL training scheme and show that it, in conjunction with automatically generated training data, leads to improvement of a pre-trained code language model's performance by up to 9.9% improvement over the original underlying code synthesis LM, and up to 4.3% over RL-based models trained with standard PPO or CodeRL.
Learnersourcing involves students generating and sharing learning resources with their peers. When learnersourcing multiple-choice questions, creating explanations for the generated questions is a crucial step as it facilitates a deeper understanding of the related concepts. However, it is often difficult for students to craft effective explanations due to limited subject understanding and a tendency to merely restate the question stem, distractors, and correct answer. To help scaffold this task, in this work we propose a self-reinforcement large-language-model framework, with the goal of generating and evaluating explanations automatically. Comprising three modules, the framework generates student-aligned explanations, evaluates these explanations to ensure their quality and iteratively enhances the explanations. If an explanation's evaluation score falls below a defined threshold, the framework iteratively refines and reassesses the explanation. Importantly, our framework emulates the manner in which students compose explanations at the relevant grade level. For evaluation, we had a human subject-matter expert compare the explanations generated by students with the explanations created by the open-source large language model Vicuna-13B, a version of Vicuna-13B that had been fine-tuned using our method, and by GPT-4. We observed that, when compared to other large language models, GPT-4 exhibited a higher level of creativity in generating explanations. We also found that explanations generated by GPT-4 were ranked higher by the human expert than both those created by the other models and the original student-created explanations. Our findings represent a significant advancement in enriching the learnersourcing experience for students and enhancing the capabilities of large language models in educational applications.
We present a novel meta-learning approach for 6D pose estimation on unknown objects. In contrast to ``instance-level" and ``category-level" pose estimation methods, our algorithm learns object representation in a category-agnostic way, which endows it with strong generalization capabilities across object categories. Specifically, we employ a neural process-based meta-learning approach to train an encoder to capture texture and geometry of an object in a latent representation, based on very few RGB-D images and ground-truth keypoints. The latent representation is then used by a simultaneously meta-trained decoder to predict the 6D pose of the object in new images. Furthermore, we propose a novel geometry-aware decoder for the keypoint prediction using a Graph Neural Network (GNN), which explicitly takes geometric constraints specific to each object into consideration. To evaluate our algorithm, extensive experiments are conducted on the \linemod dataset, and on our new fully-annotated synthetic datasets generated from Multiple Categories in Multiple Scenes (MCMS). Experimental results demonstrate that our model performs well on unseen objects with very different shapes and appearances. Remarkably, our model also shows robust performance on occluded scenes although trained fully on data without occlusion. To our knowledge, this is the first work exploring \textbf{cross-category level} 6D pose estimation.
Federated learning (FL) facilitates distributed training across clients, safeguarding the privacy of their data. The inherent distributed structure of FL introduces vulnerabilities, especially from adversarial (Byzantine) clients aiming to skew local updates to their advantage. Despite the plethora of research focusing on Byzantine-resilient FL, the academic community has yet to establish a comprehensive benchmark suite, pivotal for impartial assessment and comparison of different techniques. This paper investigates existing techniques in Byzantine-resilient FL and introduces an open-source benchmark suite for convenient and fair performance comparisons. Our investigation begins with a systematic study of Byzantine attack and defense strategies. Subsequently, we present \ours, a scalable, extensible, and easily configurable benchmark suite that supports researchers and developers in efficiently implementing and validating novel strategies against baseline algorithms in Byzantine-resilient FL. The design of \ours incorporates key characteristics derived from our systematic study, encompassing the attacker's capabilities and knowledge, defense strategy categories, and factors influencing robustness. Blades contains built-in implementations of representative attack and defense strategies and offers user-friendly interfaces for seamlessly integrating new ideas.
Great progress has been made in automatic medical image segmentation due to powerful deep representation learning. The influence of transformer has led to research into its variants, and large-scale replacement of traditional CNN modules. However, such trend often overlooks the intrinsic feature extraction capabilities of the transformer and potential refinements to both the model and the transformer module through minor adjustments. This study proposes a novel deep medical image segmentation framework, called DA-TransUNet, aiming to introduce the Transformer and dual attention block into the encoder and decoder of the traditional U-shaped architecture. Unlike prior transformer-based solutions, our DA-TransUNet utilizes attention mechanism of transformer and multifaceted feature extraction of DA-Block, which can efficiently combine global, local, and multi-scale features to enhance medical image segmentation. Meanwhile, experimental results show that a dual attention block is added before the Transformer layer to facilitate feature extraction in the U-net structure. Furthermore, incorporating dual attention blocks in skip connections can enhance feature transfer to the decoder, thereby improving image segmentation performance. Experimental results across various benchmark of medical image segmentation reveal that DA-TransUNet significantly outperforms the state-of-the-art methods. The codes and parameters of our model will be publicly available at //github.com/SUN-1024/DA-TransUnet.
Self-supervised learning (SSL) has recently achieved impressive performance on various time series tasks. The most prominent advantage of SSL is that it reduces the dependence on labeled data. Based on the pre-training and fine-tuning strategy, even a small amount of labeled data can achieve high performance. Compared with many published self-supervised surveys on computer vision and natural language processing, a comprehensive survey for time series SSL is still missing. To fill this gap, we review current state-of-the-art SSL methods for time series data in this article. To this end, we first comprehensively review existing surveys related to SSL and time series, and then provide a new taxonomy of existing time series SSL methods. We summarize these methods into three categories: generative-based, contrastive-based, and adversarial-based. All methods can be further divided into ten subcategories. To facilitate the experiments and validation of time series SSL methods, we also summarize datasets commonly used in time series forecasting, classification, anomaly detection, and clustering tasks. Finally, we present the future directions of SSL for time series analysis.
Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to physicians has long been viewed as one such grand challenge. Large language models (LLMs) have catalyzed significant progress in medical question answering; Med-PaLM was the first model to exceed a "passing" score in US Medical Licensing Examination (USMLE) style questions with a score of 67.2% on the MedQA dataset. However, this and other prior work suggested significant room for improvement, especially when models' answers were compared to clinicians' answers. Here we present Med-PaLM 2, which bridges these gaps by leveraging a combination of base LLM improvements (PaLM 2), medical domain finetuning, and prompting strategies including a novel ensemble refinement approach. Med-PaLM 2 scored up to 86.5% on the MedQA dataset, improving upon Med-PaLM by over 19% and setting a new state-of-the-art. We also observed performance approaching or exceeding state-of-the-art across MedMCQA, PubMedQA, and MMLU clinical topics datasets. We performed detailed human evaluations on long-form questions along multiple axes relevant to clinical applications. In pairwise comparative ranking of 1066 consumer medical questions, physicians preferred Med-PaLM 2 answers to those produced by physicians on eight of nine axes pertaining to clinical utility (p < 0.001). We also observed significant improvements compared to Med-PaLM on every evaluation axis (p < 0.001) on newly introduced datasets of 240 long-form "adversarial" questions to probe LLM limitations. While further studies are necessary to validate the efficacy of these models in real-world settings, these results highlight rapid progress towards physician-level performance in medical question answering.
The incredible development of federated learning (FL) has benefited various tasks in the domains of computer vision and natural language processing, and the existing frameworks such as TFF and FATE has made the deployment easy in real-world applications. However, federated graph learning (FGL), even though graph data are prevalent, has not been well supported due to its unique characteristics and requirements. The lack of FGL-related framework increases the efforts for accomplishing reproducible research and deploying in real-world applications. Motivated by such strong demand, in this paper, we first discuss the challenges in creating an easy-to-use FGL package and accordingly present our implemented package FederatedScope-GNN (FS-G), which provides (1) a unified view for modularizing and expressing FGL algorithms; (2) comprehensive DataZoo and ModelZoo for out-of-the-box FGL capability; (3) an efficient model auto-tuning component; and (4) off-the-shelf privacy attack and defense abilities. We validate the effectiveness of FS-G by conducting extensive experiments, which simultaneously gains many valuable insights about FGL for the community. Moreover, we employ FS-G to serve the FGL application in real-world E-commerce scenarios, where the attained improvements indicate great potential business benefits. We publicly release FS-G, as submodules of FederatedScope, at //github.com/alibaba/FederatedScope to promote FGL's research and enable broad applications that would otherwise be infeasible due to the lack of a dedicated package.
Object detection is a fundamental task in computer vision and image processing. Current deep learning based object detectors have been highly successful with abundant labeled data. But in real life, it is not guaranteed that each object category has enough labeled samples for training. These large object detectors are easy to overfit when the training data is limited. Therefore, it is necessary to introduce few-shot learning and zero-shot learning into object detection, which can be named low-shot object detection together. Low-Shot Object Detection (LSOD) aims to detect objects from a few or even zero labeled data, which can be categorized into few-shot object detection (FSOD) and zero-shot object detection (ZSD), respectively. This paper conducts a comprehensive survey for deep learning based FSOD and ZSD. First, this survey classifies methods for FSOD and ZSD into different categories and discusses the pros and cons of them. Second, this survey reviews dataset settings and evaluation metrics for FSOD and ZSD, then analyzes the performance of different methods on these benchmarks. Finally, this survey discusses future challenges and promising directions for FSOD and ZSD.
Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised classification in whole slide image (WSI) based pathology diagnosis. However, the current MIL methods are usually based on independent and identical distribution hypothesis, thus neglect the correlation among different instances. To address this problem, we proposed a new framework, called correlated MIL, and provided a proof for convergence. Based on this framework, we devised a Transformer based MIL (TransMIL), which explored both morphological and spatial information. The proposed TransMIL can effectively deal with unbalanced/balanced and binary/multiple classification with great visualization and interpretability. We conducted various experiments for three different computational pathology problems and achieved better performance and faster convergence compared with state-of-the-art methods. The test AUC for the binary tumor classification can be up to 93.09% over CAMELYON16 dataset. And the AUC over the cancer subtypes classification can be up to 96.03% and 98.82% over TCGA-NSCLC dataset and TCGA-RCC dataset, respectively.