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Diffuse gliomas are malignant brain tumors that grow widespread through the brain. The complex interactions between neoplastic cells and normal tissue, as well as the treatment-induced changes often encountered, make glioma tumor growth modeling challenging. In this paper, we present a novel end-to-end network capable of generating future tumor masks and realistic MRIs of how the tumor will look at any future time points for different treatment plans. Our model is built upon cutting-edge diffusion probabilistic models and deep-segmentation neural networks. We extended a diffusion model to include sequential multi-parametric MRI and treatment information as conditioning input to guide the generative diffusion process. This allows us to estimate tumor growth at any given time point. We trained the model using real-world postoperative longitudinal MRI data with glioma tumor growth trajectories represented as tumor segmentation maps over time. The model has demonstrated promising performance across a range of tasks, including the generation of high-quality synthetic MRIs with tumor masks, time-series tumor segmentations, and uncertainty estimation. Combined with the treatment-aware generated MRIs, the tumor growth predictions with uncertainty estimates can provide useful information for clinical decision-making.

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ACM/IEEE第23屆模型驅動工程語言和系統國際會議,是模型驅動軟件和系統工程的首要會議系列,由ACM-SIGSOFT和IEEE-TCSE支持組織。自1998年以來,模型涵蓋了建模的各個方面,從語言和方法到工具和應用程序。模特的參加者來自不同的背景,包括研究人員、學者、工程師和工業專業人士。MODELS 2019是一個論壇,參與者可以圍繞建模和模型驅動的軟件和系統交流前沿研究成果和創新實踐經驗。今年的版本將為建模社區提供進一步推進建模基礎的機會,并在網絡物理系統、嵌入式系統、社會技術系統、云計算、大數據、機器學習、安全、開源等新興領域提出建模的創新應用以及可持續性。 官網鏈接: · CASE · Seven · 論文 · 自然語言處理 ·
2023 年 10 月 26 日

Languages are known to describe the world in diverse ways. Across lexicons, diversity is pervasive, appearing through phenomena such as lexical gaps and untranslatability. However, in computational resources, such as multilingual lexical databases, diversity is hardly ever represented. In this paper, we introduce a method to enrich computational lexicons with content relating to linguistic diversity. The method is verified through two large-scale case studies on kinship terminology, a domain known to be diverse across languages and cultures: one case study deals with seven Arabic dialects, while the other one with three Indonesian languages. Our results, made available as browseable and downloadable computational resources, extend prior linguistics research on kinship terminology, and provide insight into the extent of diversity even within linguistically and culturally close communities.

When perceiving the world from multiple viewpoints, humans have the ability to reason about the complete objects in a compositional manner even when an object is completely occluded from certain viewpoints. Meanwhile, humans are able to imagine novel views after observing multiple viewpoints. Recent remarkable advances in multi-view object-centric learning still leaves some unresolved problems: 1) The shapes of partially or completely occluded objects can not be well reconstructed. 2) The novel viewpoint prediction depends on expensive viewpoint annotations rather than implicit rules in view representations. In this paper, we introduce a time-conditioned generative model for videos. To reconstruct the complete shape of an object accurately, we enhance the disentanglement between the latent representations of objects and views, where the latent representations of time-conditioned views are jointly inferred with a Transformer and then are input to a sequential extension of Slot Attention to learn object-centric representations. In addition, Gaussian processes are employed as priors of view latent variables for video generation and novel-view prediction without viewpoint annotations. Experiments on multiple datasets demonstrate that the proposed model can make object-centric video decomposition, reconstruct the complete shapes of occluded objects, and make novel-view predictions.

Graph Convolutional Networks (GCNs) can capture non-Euclidean spatial dependence between different brain regions. The graph pooling operator, a crucial element of GCNs, enhances the representation learning capability and facilitates the acquisition of abnormal brain maps. However, most existing research designs graph pooling operators solely from the perspective of nodes while disregarding the original edge features, in a way that not only confines graph pooling application scenarios, but also diminishes its ability to capture critical substructures. To design a graph clustering pooling operator that is tailored to dominant edge features, we proposed the edge-aware hard clustering graph pool (EHCPool) and redefined the graph clustering process. Specifically, the 'Edge-to-node' criterion was proposed to evaluate the significance of both edge and node features. Guided by edge scores, we designed a revolutionary Iteration n-top strategy, aimed at adaptively learning sparse hard clustering assignments for graphs. Subsequently, a novel N-E Aggregation strategy is introduced to aggregate node and edge information in each independent subgraph. Extensive experiments on the multi-site public datasets demonstrate the superiority and robustness of the proposed model. More notably, EHCPool has the potential to probe different types of dysfunctional brain networks from a data-driven perspective. Core code is at: //github.com/swfen/EHCPool.

Graph Convolution Networks (GCNs) manifest great potential in recommendation. This is attributed to their capability on learning good user and item embeddings by exploiting the collaborative signals from the high-order neighbors. Like other GCN models, the GCN based recommendation models also suffer from the notorious over-smoothing problem - when stacking more layers, node embeddings become more similar and eventually indistinguishable, resulted in performance degradation. The recently proposed LightGCN and LR-GCN alleviate this problem to some extent, however, we argue that they overlook an important factor for the over-smoothing problem in recommendation, that is, high-order neighboring users with no common interests of a user can be also involved in the user's embedding learning in the graph convolution operation. As a result, the multi-layer graph convolution will make users with dissimilar interests have similar embeddings. In this paper, we propose a novel Interest-aware Message-Passing GCN (IMP-GCN) recommendation model, which performs high-order graph convolution inside subgraphs. The subgraph consists of users with similar interests and their interacted items. To form the subgraphs, we design an unsupervised subgraph generation module, which can effectively identify users with common interests by exploiting both user feature and graph structure. To this end, our model can avoid propagating negative information from high-order neighbors into embedding learning. Experimental results on three large-scale benchmark datasets show that our model can gain performance improvement by stacking more layers and outperform the state-of-the-art GCN-based recommendation models significantly.

Knowledge graphs capture structured information and relations between a set of entities or items. As such they represent an attractive source of information that could help improve recommender systems. However existing approaches in this domain rely on manual feature engineering and do not allow for end-to-end training. Here we propose knowledge-aware graph neural networks with label smoothness regularization to provide better recommendations. Conceptually, our approach computes user-specific item embeddings by first applying a trainable function that identifies important knowledge graph relationships for a given user. This way we transform the knowledge graph into a user-specific weighted graph and then applies a graph neural network to compute personalized item embeddings. To provide better inductive bias, we use label smoothness, which assumes that adjacent items in the knowledge graph are likely to have similar user relevance labels/scores. Label smoothness provides regularization over edge weights and we prove that it is equivalent to a label propagation scheme on a graph. Finally, we combine knowledge-aware graph neural networks and label smoothness and present the unified model. Experiment results show that our method outperforms strong baselines in four datasets. It also achieves strong performance in the scenario where user-item interactions are sparse.

Most deep learning-based models for speech enhancement have mainly focused on estimating the magnitude of spectrogram while reusing the phase from noisy speech for reconstruction. This is due to the difficulty of estimating the phase of clean speech. To improve speech enhancement performance, we tackle the phase estimation problem in three ways. First, we propose Deep Complex U-Net, an advanced U-Net structured model incorporating well-defined complex-valued building blocks to deal with complex-valued spectrograms. Second, we propose a polar coordinate-wise complex-valued masking method to reflect the distribution of complex ideal ratio masks. Third, we define a novel loss function, weighted source-to-distortion ratio (wSDR) loss, which is designed to directly correlate with a quantitative evaluation measure. Our model was evaluated on a mixture of the Voice Bank corpus and DEMAND database, which has been widely used by many deep learning models for speech enhancement. Ablation experiments were conducted on the mixed dataset showing that all three proposed approaches are empirically valid. Experimental results show that the proposed method achieves state-of-the-art performance in all metrics, outperforming previous approaches by a large margin.

Intent classification and slot filling are two essential tasks for natural language understanding. They often suffer from small-scale human-labeled training data, resulting in poor generalization capability, especially for rare words. Recently a new language representation model, BERT (Bidirectional Encoder Representations from Transformers), facilitates pre-training deep bidirectional representations on large-scale unlabeled corpora, and has created state-of-the-art models for a wide variety of natural language processing tasks after simple fine-tuning. However, there has not been much effort on exploring BERT for natural language understanding. In this work, we propose a joint intent classification and slot filling model based on BERT. Experimental results demonstrate that our proposed model achieves significant improvement on intent classification accuracy, slot filling F1, and sentence-level semantic frame accuracy on several public benchmark datasets, compared to the attention-based recurrent neural network models and slot-gated models.

Within the rapidly developing Internet of Things (IoT), numerous and diverse physical devices, Edge devices, Cloud infrastructure, and their quality of service requirements (QoS), need to be represented within a unified specification in order to enable rapid IoT application development, monitoring, and dynamic reconfiguration. But heterogeneities among different configuration knowledge representation models pose limitations for acquisition, discovery and curation of configuration knowledge for coordinated IoT applications. This paper proposes a unified data model to represent IoT resource configuration knowledge artifacts. It also proposes IoT-CANE (Context-Aware recommendatioN systEm) to facilitate incremental knowledge acquisition and declarative context driven knowledge recommendation.

We study the problem of named entity recognition (NER) from electronic medical records, which is one of the most fundamental and critical problems for medical text mining. Medical records which are written by clinicians from different specialties usually contain quite different terminologies and writing styles. The difference of specialties and the cost of human annotation makes it particularly difficult to train a universal medical NER system. In this paper, we propose a label-aware double transfer learning framework (La-DTL) for cross-specialty NER, so that a medical NER system designed for one specialty could be conveniently applied to another one with minimal annotation efforts. The transferability is guaranteed by two components: (i) we propose label-aware MMD for feature representation transfer, and (ii) we perform parameter transfer with a theoretical upper bound which is also label aware. We conduct extensive experiments on 12 cross-specialty NER tasks. The experimental results demonstrate that La-DTL provides consistent accuracy improvement over strong baselines. Besides, the promising experimental results on non-medical NER scenarios indicate that La-DTL is potential to be seamlessly adapted to a wide range of NER tasks.

We investigate the problem of automatically determining what type of shoe left an impression found at a crime scene. This recognition problem is made difficult by the variability in types of crime scene evidence (ranging from traces of dust or oil on hard surfaces to impressions made in soil) and the lack of comprehensive databases of shoe outsole tread patterns. We find that mid-level features extracted by pre-trained convolutional neural nets are surprisingly effective descriptors for this specialized domains. However, the choice of similarity measure for matching exemplars to a query image is essential to good performance. For matching multi-channel deep features, we propose the use of multi-channel normalized cross-correlation and analyze its effectiveness. Our proposed metric significantly improves performance in matching crime scene shoeprints to laboratory test impressions. We also show its effectiveness in other cross-domain image retrieval problems: matching facade images to segmentation labels and aerial photos to map images. Finally, we introduce a discriminatively trained variant and fine-tune our system through our proposed metric, obtaining state-of-the-art performance.

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