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Background: The semantics of entities extracted from a clinical text can be dramatically altered by modifiers, including entity negation, uncertainty, conditionality, severity, and subject. Existing models for determining modifiers of clinical entities involve regular expression or features weights that are trained independently for each modifier. Methods: We develop and evaluate a multi-task transformer architecture design where modifiers are learned and predicted jointly using the publicly available SemEval 2015 Task 14 corpus and a new Opioid Use Disorder (OUD) data set that contains modifiers shared with SemEval as well as novel modifiers specific for OUD. We evaluate the effectiveness of our multi-task learning approach versus previously published systems and assess the feasibility of transfer learning for clinical entity modifiers when only a portion of clinical modifiers are shared. Results: Our approach achieved state-of-the-art results on the ShARe corpus from SemEval 2015 Task 14, showing an increase of 1.1% on weighted accuracy, 1.7% on unweighted accuracy, and 10% on micro F1 scores. Conclusions: We show that learned weights from our shared model can be effectively transferred to a new partially matched data set, validating the use of transfer learning for clinical text modifiers

Deep neural networks (DNNs) have demonstrated remarkable performance across various tasks, including image and speech recognition. However, maximizing the effectiveness of DNNs requires meticulous optimization of numerous hyperparameters and network parameters through training. Moreover, high-performance DNNs entail many parameters, which consume significant energy during training. In order to overcome these challenges, researchers have turned to spiking neural networks (SNNs), which offer enhanced energy efficiency and biologically plausible data processing capabilities, rendering them highly suitable for sensory data tasks, particularly in neuromorphic data. Despite their advantages, SNNs, like DNNs, are susceptible to various threats, including adversarial examples and backdoor attacks. Yet, the field of SNNs still needs to be explored in terms of understanding and countering these attacks. This paper delves into backdoor attacks in SNNs using neuromorphic datasets and diverse triggers. Specifically, we explore backdoor triggers within neuromorphic data that can manipulate their position and color, providing a broader scope of possibilities than conventional triggers in domains like images. We present various attack strategies, achieving an attack success rate of up to 100% while maintaining a negligible impact on clean accuracy. Furthermore, we assess these attacks' stealthiness, revealing that our most potent attacks possess significant stealth capabilities. Lastly, we adapt several state-of-the-art defenses from the image domain, evaluating their efficacy on neuromorphic data and uncovering instances where they fall short, leading to compromised performance.

The efficacy of self-supervised speech models has been validated, yet the optimal utilization of their representations remains challenging across diverse tasks. In this study, we delve into Acoustic Word Embeddings (AWEs), a fixed-length feature derived from continuous representations, to explore their advantages in specific tasks. AWEs have previously shown utility in capturing acoustic discriminability. In light of this, we propose measuring layer-wise similarity between AWEs and word embeddings, aiming to further investigate the inherent context within AWEs. Moreover, we evaluate the contribution of AWEs, in comparison to other types of speech features, in the context of Speech Emotion Recognition (SER). Through a comparative experiment and a layer-wise accuracy analysis on two distinct corpora, IEMOCAP and ESD, we explore differences between AWEs and raw self-supervised representations, as well as the proper utilization of AWEs alone and in combination with word embeddings. Our findings underscore the acoustic context conveyed by AWEs and showcase the highly competitive SER accuracies by appropriately employing AWEs.

The Butterfly Effect, a concept originating from chaos theory, underscores how small changes can have significant and unpredictable impacts on complex systems. In the context of AI fairness and bias, the Butterfly Effect can stem from a variety of sources, such as small biases or skewed data inputs during algorithm development, saddle points in training, or distribution shifts in data between training and testing phases. These seemingly minor alterations can lead to unexpected and substantial unfair outcomes, disproportionately affecting underrepresented individuals or groups and perpetuating pre-existing inequalities. Moreover, the Butterfly Effect can amplify inherent biases within data or algorithms, exacerbate feedback loops, and create vulnerabilities for adversarial attacks. Given the intricate nature of AI systems and their societal implications, it is crucial to thoroughly examine any changes to algorithms or input data for potential unintended consequences. In this paper, we envision both algorithmic and empirical strategies to detect, quantify, and mitigate the Butterfly Effect in AI systems, emphasizing the importance of addressing these challenges to promote fairness and ensure responsible AI development.

In recent years, Large Language Models (LLMs) have achieved significant success in natural language processing (NLP) and various interdisciplinary areas. However, applying LLMs to chemistry is a complex task that requires specialized domain knowledge. This paper provides a thorough exploration of the nuanced methodologies employed in integrating LLMs into the field of chemistry, delving into the complexities and innovations at this interdisciplinary juncture. Specifically, our analysis begins with examining how molecular information is fed into LLMs through various representation and tokenization methods. We then categorize chemical LLMs into three distinct groups based on the domain and modality of their input data, and discuss approaches for integrating these inputs for LLMs. Furthermore, this paper delves into the pretraining objectives with adaptations to chemical LLMs. After that, we explore the diverse applications of LLMs in chemistry, including novel paradigms for their application in chemistry tasks. Finally, we identify promising research directions, including further integration with chemical knowledge, advancements in continual learning, and improvements in model interpretability, paving the way for groundbreaking developments in the field.

In patent prosecution, timely and effective responses to Office Actions (OAs) are crucial for acquiring patents, yet past automation and AI research have scarcely addressed this aspect. To address this gap, our study introduces the Patent Office Action Response Intelligence System (PARIS) and its advanced version, the Large Language Model Enhanced PARIS (LE-PARIS). These systems are designed to expedite the efficiency of patent attorneys in collaboratively handling OA responses. The systems' key features include the construction of an OA Topics Database, development of Response Templates, and implementation of Recommender Systems and LLM-based Response Generation. Our validation involves a multi-paradigmatic analysis using the USPTO Office Action database and longitudinal data of attorney interactions with our systems over six years. Through five studies, we examine the constructiveness of OA topics (studies 1 and 2) using topic modeling and the proposed Delphi process, the efficacy of our proposed hybrid recommender system tailored for OA (both LLM-based and non-LLM-based) (study 3), the quality of response generation (study 4), and the practical value of the systems in real-world scenarios via user studies (study 5). Results demonstrate that both PARIS and LE-PARIS significantly meet key metrics and positively impact attorney performance.

The increased utilization of Artificial Intelligence (AI) solutions brings with it inherent risks, such as misclassification and sub-optimal execution time performance, due to errors introduced in their deployment infrastructure because of problematic configuration and software faults. On top of that, AI methods such as Deep Neural Networks (DNNs) are utilized to perform demanding, resource-intensive and even safety-critical tasks, and in order to effectively increase the performance of the DNN models deployed, a variety of Machine Learning (ML) compilers have been developed, allowing compatibility of DNNs with a variety of hardware acceleration devices, such as GPUs and TPUs. Furthermore the correctness of the compilation process should be verified. In order to allow developers and researchers to explore the robustness of DNN models deployed on different hardware accelerators via ML compilers, in this paper we propose MutateNN, a tool that provides mutation testing and model analysis features in the context of deployment on different hardware accelerators. To demonstrate the capabilities of MutateNN, we focus on the image recognition domain by applying mutation testing to 7 well-established models utilized for image classification. We instruct 21 mutations of 6 different categories, and deploy our mutants on 4 different hardware acceleration devices of varying capabilities. Our results indicate that models are proven robust to changes related to layer modifications and arithmetic operators, while presenting discrepancies of up to 90.3% in mutants related to conditional operators. We also observed unexpectedly severe performance degradation on mutations related to arithmetic types of variables, leading the mutants to produce the same classifications for all dataset inputs.

Artificial intelligence (AI) has become a part of everyday conversation and our lives. It is considered as the new electricity that is revolutionizing the world. AI is heavily invested in both industry and academy. However, there is also a lot of hype in the current AI debate. AI based on so-called deep learning has achieved impressive results in many problems, but its limits are already visible. AI has been under research since the 1940s, and the industry has seen many ups and downs due to over-expectations and related disappointments that have followed. The purpose of this book is to give a realistic picture of AI, its history, its potential and limitations. We believe that AI is a helper, not a ruler of humans. We begin by describing what AI is and how it has evolved over the decades. After fundamentals, we explain the importance of massive data for the current mainstream of artificial intelligence. The most common representations for AI, methods, and machine learning are covered. In addition, the main application areas are introduced. Computer vision has been central to the development of AI. The book provides a general introduction to computer vision, and includes an exposure to the results and applications of our own research. Emotions are central to human intelligence, but little use has been made in AI. We present the basics of emotional intelligence and our own research on the topic. We discuss super-intelligence that transcends human understanding, explaining why such achievement seems impossible on the basis of present knowledge,and how AI could be improved. Finally, a summary is made of the current state of AI and what to do in the future. In the appendix, we look at the development of AI education, especially from the perspective of contents at our own university.

Humans can naturally and effectively find salient regions in complex scenes. Motivated by this observation, attention mechanisms were introduced into computer vision with the aim of imitating this aspect of the human visual system. Such an attention mechanism can be regarded as a dynamic weight adjustment process based on features of the input image. Attention mechanisms have achieved great success in many visual tasks, including image classification, object detection, semantic segmentation, video understanding, image generation, 3D vision, multi-modal tasks and self-supervised learning. In this survey, we provide a comprehensive review of various attention mechanisms in computer vision and categorize them according to approach, such as channel attention, spatial attention, temporal attention and branch attention; a related repository //github.com/MenghaoGuo/Awesome-Vision-Attentions is dedicated to collecting related work. We also suggest future directions for attention mechanism research.

Graph Neural Networks (GNNs) have been studied from the lens of expressive power and generalization. However, their optimization properties are less well understood. We take the first step towards analyzing GNN training by studying the gradient dynamics of GNNs. First, we analyze linearized GNNs and prove that despite the non-convexity of training, convergence to a global minimum at a linear rate is guaranteed under mild assumptions that we validate on real-world graphs. Second, we study what may affect the GNNs' training speed. Our results show that the training of GNNs is implicitly accelerated by skip connections, more depth, and/or a good label distribution. Empirical results confirm that our theoretical results for linearized GNNs align with the training behavior of nonlinear GNNs. Our results provide the first theoretical support for the success of GNNs with skip connections in terms of optimization, and suggest that deep GNNs with skip connections would be promising in practice.