Radiotherapy treatment planning is a challenging large-scale optimization problem plagued by uncertainty. Following the robust optimization methodology, we propose a novel, spatially based uncertainty set for robust modeling of radiotherapy planning, producing solutions that are immune to unexpected changes in biological conditions. Our proposed uncertainty set realistically captures biological radiosensitivity patterns that are observed using recent advances in imaging, while its parameters can be personalized for individual patients. We exploit the structure of this set to devise a compact reformulation of the robust model. We develop a row-generation scheme to solve real, large-scale instances of the robust model. This method is then extended to a relaxation-based scheme for enforcing challenging, yet clinically important, dose-volume cardinality constraints. The computational performance of our algorithms, as well as the quality and robustness of the computed treatment plans, are demonstrated on simulated and real imaging data. Based on accepted performance measures, such as minimal target dose and homogeneity, these examples demonstrate that the spatially robust model achieves almost the same performance as the nominal model in the nominal scenario, and otherwise, the spatial model outperforms both the nominal and the box-uncertainty models.
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In the realm of autonomous driving, accurate 3D perception is the foundation. However, developing such models relies on extensive human annotations -- a process that is both costly and labor-intensive. To address this challenge from a data representation learning perspective, we introduce SuperFlow, a novel framework designed to harness consecutive LiDAR-camera pairs for establishing spatiotemporal pretraining objectives. SuperFlow stands out by integrating two key designs: 1) a dense-to-sparse consistency regularization, which promotes insensitivity to point cloud density variations during feature learning, and 2) a flow-based contrastive learning module, carefully crafted to extract meaningful temporal cues from readily available sensor calibrations. To further boost learning efficiency, we incorporate a plug-and-play view consistency module that enhances the alignment of the knowledge distilled from camera views. Extensive comparative and ablation studies across 11 heterogeneous LiDAR datasets validate our effectiveness and superiority. Additionally, we observe several interesting emerging properties by scaling up the 2D and 3D backbones during pretraining, shedding light on the future research of 3D foundation models for LiDAR-based perception.
Automation of hydraulic material handling machinery is currently limited to semi-static pick-and-place cycles. Dynamic throwing motions which utilize the passive joints, can greatly improve time efficiency as well as increase the dumping workspace. In this work, we use Reinforcement Learning (RL) to design dynamic controllers for material handlers with underactuated arms as commonly used in logistics. The controllers are tested both in simulation and in real-world experiments on a 12-ton test platform. The method is able to exploit the passive joints of the gripper to perform dynamic throwing motions. With the proposed controllers, the machine is able to throw individual objects to targets outside the static reachability zone with good accuracy for its practical applications. The work demonstrates the possibility of using RL to perform highly dynamic tasks with heavy machinery, suggesting a potential for improving the efficiency and precision of autonomous material handling tasks.
In biopharmaceutical manufacturing, fermentation processes play a critical role in productivity and profit. A fermentation process uses living cells with complex biological mechanisms, leading to high variability in the process outputs, namely, the protein and impurity levels. By building on the biological mechanisms of protein and impurity growth, we introduce a stochastic model to characterize the accumulation of the protein and impurity levels in the fermentation process. However, a common challenge in the industry is the availability of only a very limited amount of data, especially in the development and early stages of production. This adds an additional layer of uncertainty, referred to as model risk, due to the difficulty of estimating the model parameters with limited data. In this paper, we study the harvesting decision for a fermentation process (i.e., when to stop the fermentation and collect the production reward) under model risk. We adopt a Bayesian approach to update the unknown parameters of the growth-rate distributions, and use the resulting posterior distributions to characterize the impact of model risk on fermentation output variability. The harvesting problem is formulated as a Markov decision process model with knowledge states that summarize the posterior distributions and hence incorporate the model risk in decision-making. Our case studies at MSD Animal Health demonstrate that the proposed model and solution approach improve the harvesting decisions in real life by achieving substantially higher average output from a fermentation batch along with lower batch-to-batch variability.
Important tasks such as reasoning and planning are fundamentally algorithmic, meaning that solving them robustly requires acquiring true reasoning or planning algorithms, rather than shortcuts. Large Language Models lack true algorithmic ability primarily because of the limitations of neural network optimization algorithms, their optimization data and optimization objective, but also due to architectural inexpressivity. To solve this, our paper proposes augmenting LLMs with a library of fundamental operations and sophisticated differentiable programs, so that common algorithms do not need to be learned from scratch. We add memory, registers, basic operations, and adaptive recurrence to a transformer architecture built on LLaMA3. Then, we define a method for directly compiling algorithms into a differentiable starting library, which is used natively and propagates gradients for optimization. In this preliminary study, we explore the feasability of augmenting LLaMA3 with a differentiable computer, for instance by fine-tuning small transformers on simple algorithmic tasks with variable computational depth.
This paper presents a mapping strategy for interacting with the latent spaces of generative AI models. Our approach involves using unsupervised feature learning to encode a human control space and mapping it to an audio synthesis model's latent space. To demonstrate how this mapping strategy can turn high-dimensional sensor data into control mechanisms of a deep generative model, we present a proof-of-concept system that uses visual sketches to control an audio synthesis model. We draw on emerging discourses in XAIxArts to discuss how this approach can contribute to XAI in artistic and creative contexts, we also discuss its current limitations and propose future research directions.
In safety-critical robot planning or control, manually specifying safety constraints or learning them from demonstrations can be challenging. In this paper, we propose a certifiable alignment method for a robot to learn a safety constraint in its model predictive control (MPC) policy with human online directional feedback. To our knowledge, it is the first method to learn safety constraints from human feedback. The proposed method is based on an empirical observation: human directional feedback, when available, tends to guide the robot toward safer regions. The method only requires the direction of human feedback to update the learning hypothesis space. It is certifiable, providing an upper bound on the total number of human feedback in the case of successful learning of safety constraints, or declaring the misspecification of the hypothesis space, i.e., the true implicit safety constraint cannot be found within the specified hypothesis space. We evaluated the proposed method using numerical examples and user studies in two developed simulation games. Additionally, we implemented and tested the proposed method on a real-world Franka robot arm performing mobile water-pouring tasks in a user study. The simulation and experimental results demonstrate the efficacy and efficiency of our method, showing that it enables a robot to successfully learn safety constraints with a small handful (tens) of human directional corrections.
User response prediction is essential in industrial recommendation systems, such as online display advertising. Among all the features in recommendation models, user behaviors are among the most critical. Many works have revealed that a user's behavior reflects her interest in the candidate item, owing to the semantic or temporal correlation between behaviors and the candidate. While the literature has individually examined each of these correlations, researchers have yet to analyze them in combination, that is, the semantic-temporal correlation. We empirically measure this correlation and observe intuitive yet robust patterns. We then examine several popular user interest models and find that, surprisingly, none of them learn such correlation well. To fill this gap, we propose a Temporal Interest Network (TIN) to capture the semantic-temporal correlation simultaneously between behaviors and the target. We achieve this by incorporating target-aware temporal encoding, in addition to semantic encoding, to represent behaviors and the target. Furthermore, we conduct explicit 4-way interaction by deploying target-aware attention and target-aware representation to capture both semantic and temporal correlation. We conduct comprehensive evaluations on two popular public datasets, and our proposed TIN outperforms the best-performing baselines by 0.43% and 0.29% on GAUC, respectively. During online A/B testing in Tencent's advertising platform, TIN achieves 1.65% cost lift and 1.93% GMV lift over the base model. It has been successfully deployed in production since October 2023, serving the WeChat Moments traffic. We have released our code at //github.com/zhouxy1003/TIN.
Aspect based sentiment analysis (ABSA) can provide more detailed information than general sentiment analysis, because it aims to predict the sentiment polarities of the given aspects or entities in text. We summarize previous approaches into two subtasks: aspect-category sentiment analysis (ACSA) and aspect-term sentiment analysis (ATSA). Most previous approaches employ long short-term memory and attention mechanisms to predict the sentiment polarity of the concerned targets, which are often complicated and need more training time. We propose a model based on convolutional neural networks and gating mechanisms, which is more accurate and efficient. First, the novel Gated Tanh-ReLU Units can selectively output the sentiment features according to the given aspect or entity. The architecture is much simpler than attention layer used in the existing models. Second, the computations of our model could be easily parallelized during training, because convolutional layers do not have time dependency as in LSTM layers, and gating units also work independently. The experiments on SemEval datasets demonstrate the efficiency and effectiveness of our models.
Deep neural networks (DNNs) have been found to be vulnerable to adversarial examples resulting from adding small-magnitude perturbations to inputs. Such adversarial examples can mislead DNNs to produce adversary-selected results. Different attack strategies have been proposed to generate adversarial examples, but how to produce them with high perceptual quality and more efficiently requires more research efforts. In this paper, we propose AdvGAN to generate adversarial examples with generative adversarial networks (GANs), which can learn and approximate the distribution of original instances. For AdvGAN, once the generator is trained, it can generate adversarial perturbations efficiently for any instance, so as to potentially accelerate adversarial training as defenses. We apply AdvGAN in both semi-whitebox and black-box attack settings. In semi-whitebox attacks, there is no need to access the original target model after the generator is trained, in contrast to traditional white-box attacks. In black-box attacks, we dynamically train a distilled model for the black-box model and optimize the generator accordingly. Adversarial examples generated by AdvGAN on different target models have high attack success rate under state-of-the-art defenses compared to other attacks. Our attack has placed the first with 92.76% accuracy on a public MNIST black-box attack challenge.
Multi-relation Question Answering is a challenging task, due to the requirement of elaborated analysis on questions and reasoning over multiple fact triples in knowledge base. In this paper, we present a novel model called Interpretable Reasoning Network that employs an interpretable, hop-by-hop reasoning process for question answering. The model dynamically decides which part of an input question should be analyzed at each hop; predicts a relation that corresponds to the current parsed results; utilizes the predicted relation to update the question representation and the state of the reasoning process; and then drives the next-hop reasoning. Experiments show that our model yields state-of-the-art results on two datasets. More interestingly, the model can offer traceable and observable intermediate predictions for reasoning analysis and failure diagnosis.
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