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This paper addresses the problem of statistical inference for latent continuous-time stochastic processes, which is often intractable, particularly for discrete state space processes described by Markov jump processes. To overcome this issue, we propose a new tractable inference scheme based on an entropic matching framework that can be embedded into the well-known expectation propagation algorithm. We demonstrate the effectiveness of our method by providing closed-form results for a simple family of approximate distributions and apply it to the general class of chemical reaction networks, which are a crucial tool for modeling in systems biology. Moreover, we derive closed form expressions for point estimation of the underlying parameters using an approximate expectation maximization procedure. We evaluate the performance of our method on various chemical reaction network instantiations, including a stochastic Lotka-Voltera example, and discuss its limitations and potential for future improvements. Our proposed approach provides a promising direction for addressing complex continuous-time Bayesian inference problems.

We propose a general framework for obtaining probabilistic solutions to PDE-based inverse problems. Bayesian methods are attractive for uncertainty quantification but assume knowledge of the likelihood model or data generation process. This assumption is difficult to justify in many inverse problems, where the specification of the data generation process is not obvious. We adopt a Gibbs posterior framework that directly posits a regularized variational problem on the space of probability distributions of the parameter. We propose a novel model comparison framework that evaluates the optimality of a given loss based on its "predictive performance". We provide cross-validation procedures to calibrate the regularization parameter of the variational objective and compare multiple loss functions. Some novel theoretical properties of Gibbs posteriors are also presented. We illustrate the utility of our framework via a simulated example, motivated by dispersion-based wave models used to characterize arterial vessels in ultrasound vibrometry.

This scientific paper explores two distinct approaches for identifying and approximating the simulation model, particularly in the context of the snap process crucial to medical device assembly. Simulation models play a pivotal role in providing engineers with insights into industrial processes, enabling experimentation and troubleshooting before physical assembly. However, their complexity often results in time-consuming computations. To mitigate this complexity, we present two distinct methods for identifying simulation models: one utilizing Spline functions and the other harnessing Machine Learning (ML) models. Our goal is to create adaptable models that accurately represent the snap process and can accommodate diverse scenarios. Such models hold promise for enhancing process understanding and aiding in decision-making, especially when data availability is limited.

We present a generalized linear structural causal model, coupled with a novel data-adaptive linear regularization, to recover causal directed acyclic graphs (DAGs) from time series. By leveraging a recently developed stochastic monotone Variational Inequality (VI) formulation, we cast the causal discovery problem as a general convex optimization. Furthermore, we develop a non-asymptotic recovery guarantee and quantifiable uncertainty by solving a linear program to establish confidence intervals for a wide range of non-linear monotone link functions. We validate our theoretical results and show the competitive performance of our method via extensive numerical experiments. Most importantly, we demonstrate the effectiveness of our approach in recovering highly interpretable causal DAGs over Sepsis Associated Derangements (SADs) while achieving comparable prediction performance to powerful ``black-box'' models such as XGBoost. Thus, the future adoption of our proposed method to conduct continuous surveillance of high-risk patients by clinicians is much more likely.

This paper presents a novel framework to realize proprioception and closed-loop control for soft manipulators. Deformations with large elongation and large bending can be precisely predicted using geometry-based sensor signals obtained from the inductive springs and the inertial measurement units (IMUs) with the help of machine learning techniques. Multiple geometric signals are fused into robust pose estimations, and a data-efficient training process is achieved after applying the strategy of sim-to-real transfer. As a result, we can achieve proprioception that is robust to the variation of external loading and has an average error of 0.7% across the workspace on a pneumatic-driven soft manipulator. The realized proprioception on soft manipulator is then contributed to building a sensor-space based algorithm for closed-loop control. A gradient descent solver is developed to drive the end-effector to achieve the required poses by iteratively computing a sequence of reference sensor signals. A conventional controller is employed in the inner loop of our algorithm to update actuators (i.e., the pressures in chambers) for approaching a reference signal in the sensor-space. The systematic function of closed-loop control has been demonstrated in tasks like path following and pick-and-place under different external loads.

This paper tackles the challenging task of evaluating socially situated conversational robots and presents a novel objective evaluation approach that relies on multimodal user behaviors. In this study, our main focus is on assessing the human-likeness of the robot as the primary evaluation metric. While previous research often relied on subjective evaluations from users, our approach aims to evaluate the robot's human-likeness based on observable user behaviors indirectly, thus enhancing objectivity and reproducibility. To begin, we created an annotated dataset of human-likeness scores, utilizing user behaviors found in an attentive listening dialogue corpus. We then conducted an analysis to determine the correlation between multimodal user behaviors and human-likeness scores, demonstrating the feasibility of our proposed behavior-based evaluation method.

Previous efforts on reconfigurable analog circuits mostly focused on specialized analog circuits, produced through careful co-design, or on highly reconfigurable, but relatively resource inefficient, accelerators that implement analog compute paradigms. This work deals with an intermediate point in the design space: Specialized reconfigurable circuits for analog compute paradigms. This class of circuits requires new methodologies for performing co-design, as prior techniques are typically highly specialized to conventional circuit classes (e.g., filters, ADCs). In this context, we present Ark, a programming language for describing analog compute paradigms. Ark enables progressive incorporation of analog behaviors into computations, and deploys a validator and dynamical system compiler for verifying and simulating computations. We use Ark to codify the design space for three different exemplary circuit design problems, and demonstrate that Ark helps exploring design trade-offs and evaluating the impact of nonidealities to the computation.

Ordered sequences of data, specified with a join operation to combine sequences, serve as a foundation for the implementation of parallel functional algorithms. This abstract data type can be elegantly and efficiently implemented using balanced binary trees, where a join operation is provided to combine two trees and rebalance as necessary. In this work, we present a verified implementation and cost analysis of joinable red-black trees in $\textbf{calf}$, a dependent type theory for cost analysis. We implement red-black trees and auxiliary intermediate data structures in such a way that all correctness invariants are intrinsically maintained. Then, we describe and verify precise cost bounds on the operations, making use of the red-black tree invariants. Finally, we implement standard algorithms on sequences using the simple join-based signature and bound their cost in the case that red-black trees are used as the underlying implementation. All proofs are formally mechanized using the embedding of $\textbf{calf}$ in the Agda theorem prover.

We introduce a multi-task setup of identifying and classifying entities, relations, and coreference clusters in scientific articles. We create SciERC, a dataset that includes annotations for all three tasks and develop a unified framework called Scientific Information Extractor (SciIE) for with shared span representations. The multi-task setup reduces cascading errors between tasks and leverages cross-sentence relations through coreference links. Experiments show that our multi-task model outperforms previous models in scientific information extraction without using any domain-specific features. We further show that the framework supports construction of a scientific knowledge graph, which we use to analyze information in scientific literature.

We propose a new method for event extraction (EE) task based on an imitation learning framework, specifically, inverse reinforcement learning (IRL) via generative adversarial network (GAN). The GAN estimates proper rewards according to the difference between the actions committed by the expert (or ground truth) and the agent among complicated states in the environment. EE task benefits from these dynamic rewards because instances and labels yield to various extents of difficulty and the gains are expected to be diverse -- e.g., an ambiguous but correctly detected trigger or argument should receive high gains -- while the traditional RL models usually neglect such differences and pay equal attention on all instances. Moreover, our experiments also demonstrate that the proposed framework outperforms state-of-the-art methods, without explicit feature engineering.