There is an increasing interest in developing LLMs for medical diagnosis to improve diagnosis efficiency. Despite their alluring technological potential, there is no unified and comprehensive evaluation criterion, leading to the inability to evaluate the quality and potential risks of medical LLMs, further hindering the application of LLMs in medical treatment scenarios. Besides, current evaluations heavily rely on labor-intensive interactions with LLMs to obtain diagnostic dialogues and human evaluation on the quality of diagnosis dialogue. To tackle the lack of unified and comprehensive evaluation criterion, we first initially establish an evaluation criterion, termed LLM-specific Mini-CEX to assess the diagnostic capabilities of LLMs effectively, based on original Mini-CEX. To address the labor-intensive interaction problem, we develop a patient simulator to engage in automatic conversations with LLMs, and utilize ChatGPT for evaluating diagnosis dialogues automatically. Experimental results show that the LLM-specific Mini-CEX is adequate and necessary to evaluate medical diagnosis dialogue. Besides, ChatGPT can replace manual evaluation on the metrics of humanistic qualities and provides reproducible and automated comparisons between different LLMs.
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Brain metastases (BMs) are the most frequently occurring brain tumors. The treatment of patients having multiple BMs with stereo tactic radiosurgery necessitates accurate localization of the metastases. Neural networks can assist in this time-consuming and costly task that is typically performed by human experts. Particularly challenging is the detection of small lesions since they are often underrepresented in exist ing approaches. Yet, lesion detection is equally important for all sizes. In this work, we develop an ensemble of neural networks explicitly fo cused on detecting and segmenting small BMs. To accomplish this task, we trained several neural networks focusing on individual aspects of the BM segmentation problem: We use blob loss that specifically addresses the imbalance of lesion instances in terms of size and texture and is, therefore, not biased towards larger lesions. In addition, a model using a subtraction sequence between the T1 and T1 contrast-enhanced sequence focuses on low-contrast lesions. Furthermore, we train additional models only on small lesions. Our experiments demonstrate the utility of the ad ditional blob loss and the subtraction sequence. However, including the specialized small lesion models in the ensemble deteriorates segmentation results. We also find domain-knowledge-inspired postprocessing steps to drastically increase our performance in most experiments. Our approach enables us to submit a competitive challenge entry to the ASNR-MICCAI BraTS Brain Metastasis Challenge 2023.
Large Language Models (LLMs) have shown promise in the autonomous driving sector, particularly in generalization and interpretability. We introduce a unique object-level multimodal LLM architecture that merges vectorized numeric modalities with a pre-trained LLM to improve context understanding in driving situations. We also present a new dataset of 160k QA pairs derived from 10k driving scenarios, paired with high quality control commands collected with RL agent and question answer pairs generated by teacher LLM (GPT-3.5). A distinct pretraining strategy is devised to align numeric vector modalities with static LLM representations using vector captioning language data. We also introduce an evaluation metric for Driving QA and demonstrate our LLM-driver's proficiency in interpreting driving scenarios, answering questions, and decision-making. Our findings highlight the potential of LLM-based driving action generation in comparison to traditional behavioral cloning. We make our benchmark, datasets, and model available for further exploration.
The goal of semantic communication is to surpass optimal Shannon's criterion regarding a notable problem for future communication which lies in the integration of collaborative efforts between the intelligence of the transmission source and the joint design of source coding and channel coding. The convergence of scholarly investigation and applicable products in the field of semantic communication is facilitated by the utilization of flexible structural hardware design, which is constrained by the computational capabilities of edge devices. This characteristic represents a significant benefit of joint source-channel coding (JSCC), as it enables the generation of source alphabets with diverse lengths and achieves a code rate of unity. Moreover, JSCC exhibits near-capacity performance while maintaining low complexity. Therefore, we leverage not only quasi-cyclic (QC) characteristics to propose a QC-LDPC code-based JSCC scheme but also Unequal Error Protection (UEP) to ensure the recovery of semantic importance. In this study, the feasibility for using a semantic encoder/decoder that is aware of UEP can be explored based on the existing JSCC system. This approach is aimed at protecting the significance of semantic task-oriented information. Additionally, the deployment of a JSCC system can be facilitated by employing Low-Density Parity-Check (LDPC) codes on a reconfigurable device. This is achieved by reconstructing the LDPC codes as QC-LDPC codes. The QC-LDPC layered decoding technique, which has been specifically optimized for hardware parallelism and tailored for channel decoding applications, can be suitably adapted to accommodate the JSCC system. The performance of the proposed system is evaluated by conducting BER measurements using both floating-point and 6-bit quantization.
Deployable Large Language Models (LLMs) must conform to the criterion of helpfulness and harmlessness, thereby achieving consistency between LLMs outputs and human values. Red-teaming techniques constitute a critical way towards this criterion. Existing work rely solely on manual red team designs and heuristic adversarial prompts for vulnerability detection and optimization. These approaches lack rigorous mathematical formulation, thus limiting the exploration of diverse attack strategy within quantifiable measure and optimization of LLMs under convergence guarantees. In this paper, we present Red-teaming Game (RTG), a general game-theoretic framework without manual annotation. RTG is designed for analyzing the multi-turn attack and defense interactions between Red-team language Models (RLMs) and Blue-team Language Model (BLM). Within the RTG, we propose Gamified Red-teaming Solver (GRTS) with diversity measure of the semantic space. GRTS is an automated red teaming technique to solve RTG towards Nash equilibrium through meta-game analysis, which corresponds to the theoretically guaranteed optimization direction of both RLMs and BLM. Empirical results in multi-turn attacks with RLMs show that GRTS autonomously discovered diverse attack strategies and effectively improved security of LLMs, outperforming existing heuristic red-team designs. Overall, RTG has established a foundational framework for red teaming tasks and constructed a new scalable oversight technique for alignment.
Depth estimation provides an alternative approach for perceiving 3D information in autonomous driving. Monocular depth estimation, whether with single-frame or multi-frame inputs, has achieved significant success by learning various types of cues and specializing in either static or dynamic scenes. Recently, these cues fusion becomes an attractive topic, aiming to enable the combined cues to perform well in both types of scenes. However, adaptive cue fusion relies on attention mechanisms, where the quadratic complexity limits the granularity of cue representation. Additionally, explicit cue fusion depends on precise segmentation, which imposes a heavy burden on mask prediction. To address these issues, we propose the GSDC Transformer, an efficient and effective component for cue fusion in monocular multi-frame depth estimation. We utilize deformable attention to learn cue relationships at a fine scale, while sparse attention reduces computational requirements when granularity increases. To compensate for the precision drop in dynamic scenes, we represent scene attributes in the form of super tokens without relying on precise shapes. Within each super token attributed to dynamic scenes, we gather its relevant cues and learn local dense relationships to enhance cue fusion. Our method achieves state-of-the-art performance on the KITTI dataset with efficient fusion speed.
Building an interactive AI assistant that can perceive, reason, and collaborate with humans in the real world has been a long-standing pursuit in the AI community. This work is part of a broader research effort to develop intelligent agents that can interactively guide humans through performing tasks in the physical world. As a first step in this direction, we introduce HoloAssist, a large-scale egocentric human interaction dataset, where two people collaboratively complete physical manipulation tasks. The task performer executes the task while wearing a mixed-reality headset that captures seven synchronized data streams. The task instructor watches the performer's egocentric video in real time and guides them verbally. By augmenting the data with action and conversational annotations and observing the rich behaviors of various participants, we present key insights into how human assistants correct mistakes, intervene in the task completion procedure, and ground their instructions to the environment. HoloAssist spans 166 hours of data captured by 350 unique instructor-performer pairs. Furthermore, we construct and present benchmarks on mistake detection, intervention type prediction, and hand forecasting, along with detailed analysis. We expect HoloAssist will provide an important resource for building AI assistants that can fluidly collaborate with humans in the real world. Data can be downloaded at //holoassist.github.io/.
Recent research in decoding methods for Natural Language Generation (NLG) tasks has shown that MAP decoding is not optimal, because model probabilities do not always align with human preferences. Stronger decoding methods, including Quality Estimation (QE) reranking and Minimum Bayes' Risk (MBR) decoding, have since been proposed to mitigate the model-perplexity-vs-quality mismatch. While these decoding methods achieve state-of-the-art performance, they are prohibitively expensive to compute. In this work, we propose MBR finetuning and QE finetuning which distill the quality gains from these decoding methods at training time, while using an efficient decoding algorithm at inference time. Using the canonical NLG task of Neural Machine Translation (NMT), we show that even with self-training, these finetuning methods significantly outperform the base model. Moreover, when using an external LLM as a teacher model, these finetuning methods outperform finetuning on human-generated references. These findings suggest new ways to leverage monolingual data to achieve improvements in model quality that are on par with, or even exceed, improvements from human-curated data, while maintaining maximum efficiency during decoding.
Applying artificial intelligence techniques in medical imaging is one of the most promising areas in medicine. However, most of the recent success in this area highly relies on large amounts of carefully annotated data, whereas annotating medical images is a costly process. In this paper, we propose a novel method, called FocalMix, which, to the best of our knowledge, is the first to leverage recent advances in semi-supervised learning (SSL) for 3D medical image detection. We conducted extensive experiments on two widely used datasets for lung nodule detection, LUNA16 and NLST. Results show that our proposed SSL methods can achieve a substantial improvement of up to 17.3% over state-of-the-art supervised learning approaches with 400 unlabeled CT scans.
Many tasks in natural language processing can be viewed as multi-label classification problems. However, most of the existing models are trained with the standard cross-entropy loss function and use a fixed prediction policy (e.g., a threshold of 0.5) for all the labels, which completely ignores the complexity and dependencies among different labels. In this paper, we propose a meta-learning method to capture these complex label dependencies. More specifically, our method utilizes a meta-learner to jointly learn the training policies and prediction policies for different labels. The training policies are then used to train the classifier with the cross-entropy loss function, and the prediction policies are further implemented for prediction. Experimental results on fine-grained entity typing and text classification demonstrate that our proposed method can obtain more accurate multi-label classification results.
Many natural language processing tasks solely rely on sparse dependencies between a few tokens in a sentence. Soft attention mechanisms show promising performance in modeling local/global dependencies by soft probabilities between every two tokens, but they are not effective and efficient when applied to long sentences. By contrast, hard attention mechanisms directly select a subset of tokens but are difficult and inefficient to train due to their combinatorial nature. In this paper, we integrate both soft and hard attention into one context fusion model, "reinforced self-attention (ReSA)", for the mutual benefit of each other. In ReSA, a hard attention trims a sequence for a soft self-attention to process, while the soft attention feeds reward signals back to facilitate the training of the hard one. For this purpose, we develop a novel hard attention called "reinforced sequence sampling (RSS)", selecting tokens in parallel and trained via policy gradient. Using two RSS modules, ReSA efficiently extracts the sparse dependencies between each pair of selected tokens. We finally propose an RNN/CNN-free sentence-encoding model, "reinforced self-attention network (ReSAN)", solely based on ReSA. It achieves state-of-the-art performance on both Stanford Natural Language Inference (SNLI) and Sentences Involving Compositional Knowledge (SICK) datasets.
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