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We develop $(\epsilon,\delta)$-differentially private projection-depth-based medians using the propose-test-release (PTR) and exponential mechanisms. Under general conditions on the input parameters and the population measure, (e.g. we do not assume any moment bounds), we quantify the probability the test in PTR fails, as well as the cost of privacy via finite sample deviation bounds. We demonstrate our main result on the canonical projection-depth-based median. In the Gaussian setting, we show that the resulting deviation bound matches the known lower bound for private Gaussian mean estimation, up to a polynomial function of the condition number of the covariance matrix. In the Cauchy setting, we show that the ``outlier error amplification'' effect resulting from the heavy tails outweighs the cost of privacy. This result is then verified via numerical simulations. Additionally, we present results on general PTR mechanisms and a uniform concentration result on the projected spacings of order statistics.

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Current quantum hardware prohibits any direct use of large classical datasets. Coresets allow for a succinct description of these large datasets and their solution in a computational task is competitive with the solution on the original dataset. The method of combining coresets with small quantum computers to solve a given task that requires a large number of data points was first introduced by Harrow [arXiv:2004.00026]. In this paper, we apply the coreset method in three different well-studied classical machine learning problems, namely Divisive Clustering, 3-means Clustering, and Gaussian Mixture Model Clustering. We provide a Hamiltonian formulation of the aforementioned problems for which the number of qubits scales linearly with the size of the coreset. Then, we evaluate how the variational quantum eigensolver (VQE) performs on these problems and demonstrate the practical efficiency of coresets when used along with a small quantum computer. We perform noiseless simulations on instances of sizes up to 25 qubits on CUDA Quantum and show that our approach provides comparable performance to classical solvers.

We give an alternative derivation of $(N,N)$-isogenies between fastKummer surfaces which complements existing works based on the theory oftheta functions. We use this framework to produce explicit formulae for thecase of $N = 3$, and show that the resulting algorithms are more efficient thanall prior $(3, 3)$-isogeny algorithms.

Municipalities are vulnerable to cyberattacks with devastating consequences, but they lack key information to evaluate their own risk and compare their security posture to peers. Using data from 83 municipalities collected via a cryptographically secure computation platform about their security posture, incidents, security control failures, and losses, we build data-driven cyber risk models and cyber security benchmarks for municipalities. We produce benchmarks of the security posture in a sector, the frequency of cyber incidents, forecasted annual losses for organizations based on their defensive posture, and a weighting of cyber controls based on their individual failure rates and associated losses. Combined, these four items can help guide cyber policymaking by quantifying the cyber risk in a sector, identifying gaps that need to be addressed, prioritizing policy interventions, and tracking progress of those interventions over time. In the case of the municipalities, these newly derived risk measures highlight the need for continuous measured improvement of cybersecurity readiness, show clear areas of weakness and strength, and provide governments with some early targets for policy focus such as security education, incident response, and focusing efforts first on municipalities at the lowest security levels that have the highest risk reduction per security dollar invested.

Neural operators (NO) are discretization invariant deep learning methods with functional output and can approximate any continuous operator. NO have demonstrated the superiority of solving partial differential equations (PDEs) over other deep learning methods. However, the spatial domain of its input function needs to be identical to its output, which limits its applicability. For instance, the widely used Fourier neural operator (FNO) fails to approximate the operator that maps the boundary condition to the PDE solution. To address this issue, we propose a novel framework called resolution-invariant deep operator (RDO) that decouples the spatial domain of the input and output. RDO is motivated by the Deep operator network (DeepONet) and it does not require retraining the network when the input/output is changed compared with DeepONet. RDO takes functional input and its output is also functional so that it keeps the resolution invariant property of NO. It can also resolve PDEs with complex geometries whereas NO fail. Various numerical experiments demonstrate the advantage of our method over DeepONet and FNO.

This note presents a method that provides optimal monotone conditional error functions for a large class of adaptive two stage designs. The presented method builds on a previously developed general theory for optimal adaptive two stage designs where sample sizes are reassessed for a specific conditional power and the goal is to minimize the expected sample size. The previous theory can easily lead to a non-monotonous conditional error function which is highly undesirable for logical reasons and can harm type I error rate control for composite null hypotheses. The here presented method extends the existing theory by introducing intermediate monotonising steps that can easily be implemented.

Clusters of similar or dissimilar objects are encountered in many fields. Frequently used approaches treat the central object of each cluster as latent. Yet, often objects of one or more types cluster around objects of another type. Such arrangements are common in biomedical images of cells, in which nearby cell types likely interact. Quantifying spatial relationships may elucidate biological mechanisms. Parent-offspring statistical frameworks can be usefully applied even when central objects (parents) differ from peripheral ones (offspring). We propose the novel multivariate cluster point process (MCPP) to quantify multi-object (e.g., multi-cellular) arrangements. Unlike commonly used approaches, the MCPP exploits locations of the central parent object in clusters. It accounts for possibly multilayered, multivariate clustering. The model formulation requires specification of which object types function as cluster centers and which reside peripherally. If such information is unknown, the relative roles of object types may be explored by comparing fit of different models via the deviance information criterion (DIC). In simulated data, we compared DIC of a series of models; the MCPP correctly identified simulated relationships. It also produced more accurate and precise parameter estimates than the classical univariate Neyman-Scott process model. We also used the MCPP to quantify proposed configurations and explore new ones in human dental plaque biofilm image data. MCPP models quantified simultaneous clustering of Streptococcus and Porphyromonas around Corynebacterium and of Pasteurellaceae around Streptococcus and successfully captured hypothesized structures for all taxa. Further exploration suggested the presence of clustering between Fusobacterium and Leptotrichia, a previously unreported relationship.

The differences between cloze-task language model (LM) probing with 1) expert-made templates and 2) naturally-occurring text have often been overlooked. Here, we evaluate 16 different LMs on 10 probing English datasets -- 4 template-based and 6 template-free -- in general and biomedical domains to answer the following research questions: (RQ1) Do model rankings differ between the two approaches? (RQ2) Do models' absolute scores differ between the two approaches? (RQ3) Do the answers to RQ1 and RQ2 differ between general and domain-specific models? Our findings are: 1) Template-free and template-based approaches often rank models differently, except for the top domain-specific models. 2) Scores decrease by up to 42% Acc@1 when comparing parallel template-free and template-based prompts. 3) Perplexity is negatively correlated with accuracy in the template-free approach, but, counter-intuitively, they are positively correlated for template-based probing. 4) Models tend to predict the same answers frequently across prompts for template-based probing, which is less common when employing template-free techniques.

The problem of estimating a parameter in the drift coefficient is addressed for $N$ discretely observed independent and identically distributed stochastic differential equations (SDEs). This is done considering additional constraints, wherein only public data can be published and used for inference. The concept of local differential privacy (LDP) is formally introduced for a system of stochastic differential equations. The objective is to estimate the drift parameter by proposing a contrast function based on a pseudo-likelihood approach. A suitably scaled Laplace noise is incorporated to meet the privacy requirements. Our key findings encompass the derivation of explicit conditions tied to the privacy level. Under these conditions, we establish the consistency and asymptotic normality of the associated estimator. Notably, the convergence rate is intricately linked to the privacy level, and is some situations may be completely different from the case where privacy constraints are ignored. Our results hold true as the discretization step approaches zero and the number of processes $N$ tends to infinity.

Among semiparametric regression models, partially linear additive models provide a useful tool to include additive nonparametric components as well as a parametric component, when explaining the relationship between the response and a set of explanatory variables. This paper concerns such models under sparsity assumptions for the covariates included in the linear component. Sparse covariates are frequent in regression problems where the task of variable selection is usually of interest. As in other settings, outliers either in the residuals or in the covariates involved in the linear component have a harmful effect. To simultaneously achieve model selection for the parametric component of the model and resistance to outliers, we combine preliminary robust estimators of the additive component, robust linear $MM-$regression estimators with a penalty such as SCAD on the coefficients in the parametric part. Under mild assumptions, consistency results and rates of convergence for the proposed estimators are derived. A Monte Carlo study is carried out to compare, under different models and contamination schemes, the performance of the robust proposal with its classical counterpart. The obtained results show the advantage of using the robust approach. Through the analysis of a real data set, we also illustrate the benefits of the proposed procedure.

Diffusion models have recently emerged as a promising framework for Image Restoration (IR), owing to their ability to produce high-quality reconstructions and their compatibility with established methods. Existing methods for solving noisy inverse problems in IR, considers the pixel-wise data-fidelity. In this paper, we propose SaFaRI, a spatial-and-frequency-aware diffusion model for IR with Gaussian noise. Our model encourages images to preserve data-fidelity in both the spatial and frequency domains, resulting in enhanced reconstruction quality. We comprehensively evaluate the performance of our model on a variety of noisy inverse problems, including inpainting, denoising, and super-resolution. Our thorough evaluation demonstrates that SaFaRI achieves state-of-the-art performance on both the ImageNet datasets and FFHQ datasets, outperforming existing zero-shot IR methods in terms of LPIPS and FID metrics.

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