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Recently, U-shaped networks have dominated the field of medical image segmentation due to their simple and easily tuned structure. However, existing U-shaped segmentation networks: 1) mostly focus on designing complex self-attention modules to compensate for the lack of long-term dependence based on convolution operation, which increases the overall number of parameters and computational complexity of the network; 2) simply fuse the features of encoder and decoder, ignoring the connection between their spatial locations. In this paper, we rethink the above problem and build a lightweight medical image segmentation network, called SegNetr. Specifically, we introduce a novel SegNetr block that can perform local-global interactions dynamically at any stage and with only linear complexity. At the same time, we design a general information retention skip connection (IRSC) to preserve the spatial location information of encoder features and achieve accurate fusion with the decoder features. We validate the effectiveness of SegNetr on four mainstream medical image segmentation datasets, with 59\% and 76\% fewer parameters and GFLOPs than vanilla U-Net, while achieving segmentation performance comparable to state-of-the-art methods. Notably, the components proposed in this paper can be applied to other U-shaped networks to improve their segmentation performance.

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The absence of annotated sign language datasets has hindered the development of sign language recognition and translation technologies. In this paper, we introduce Bornil; a crowdsource-friendly, multilingual sign language data collection, annotation, and validation platform. Bornil allows users to record sign language gestures and lets annotators perform sentence and gloss-level annotation. It also allows validators to make sure of the quality of both the recorded videos and the annotations through manual validation to develop high-quality datasets for deep learning-based Automatic Sign Language Recognition. To demonstrate the system's efficacy; we collected the largest sign language dataset for Bangladeshi Sign Language dialect, perform deep learning based Sign Language Recognition modeling, and report the benchmark performance. The Bornil platform, BornilDB v1.0 Dataset, and the codebases are available on //bornil.bengali.ai

A popular approach to model interactions is to represent them as a network with nodes being the agents and the interactions being the edges. Interactions are often timestamped, which leads to having timestamped edges. Many real-world temporal networks have a recurrent or possibly cyclic behaviour. For example, social network activity may be heightened during certain hours of day. In this paper, our main interest is to model recurrent activity in such temporal networks. As a starting point we use stochastic block model, a popular choice for modelling static networks, where nodes are split into $R$ groups. We extend this model to temporal networks by modelling the edges with a Poisson process. We make the parameters of the process dependent on time by segmenting the time line into $K$ segments. To enforce the recurring activity we require that only $H < K$ different set of parameters can be used, that is, several, not necessarily consecutive, segments must share their parameters. We prove that the searching for optimal blocks and segmentation is an NP-hard problem. Consequently, we split the problem into 3 subproblems where we optimize blocks, model parameters, and segmentation in turn while keeping the remaining structures fixed. We propose an iterative algorithm that requires $O(KHm + Rn + R^2H)$ time per iteration, where $n$ and $m$ are the number of nodes and edges in the network. We demonstrate experimentally that the number of required iterations is typically low, the algorithm is able to discover the ground truth from synthetic datasets, and show that certain real-world networks exhibit recurrent behaviour as the likelihood does not deteriorate when $H$ is lowered.

We consider a broad class of random bipartite networks, the distribution of which is invariant under permutation within each type of nodes. We are interested in $U$-statistics defined on the adjacency matrix of such a network, for which we define a new type of Hoeffding decomposition. This decomposition enables us to characterize non-degenerate $U$-statistics -- which are then asymptotically normal -- and provides us with a natural and easy-to-implement estimator of their asymptotic variance. \\ We illustrate the use of this general approach on some typical random graph models and use it to estimate or test some quantities characterizing the topology of the associated network. We also assess the accuracy and the power of the proposed estimates or tests, via a simulation study.

Diffractive deep neural networks (D2NNs) are composed of successive transmissive layers optimized using supervised deep learning to all-optically implement various computational tasks between an input and output field-of-view (FOV). Here, we present a pyramid-structured diffractive optical network design (which we term P-D2NN), optimized specifically for unidirectional image magnification and demagnification. In this P-D2NN design, the diffractive layers are pyramidally scaled in alignment with the direction of the image magnification or demagnification. Our analyses revealed the efficacy of this P-D2NN design in unidirectional image magnification and demagnification tasks, producing high-fidelity magnified or demagnified images in only one direction, while inhibiting the image formation in the opposite direction - confirming the desired unidirectional imaging operation. Compared to the conventional D2NN designs with uniform-sized successive diffractive layers, P-D2NN design achieves similar performance in unidirectional magnification tasks using only half of the diffractive degrees of freedom within the optical processor volume. Furthermore, it maintains its unidirectional image magnification/demagnification functionality across a large band of illumination wavelengths despite being trained with a single illumination wavelength. With this pyramidal architecture, we also designed a wavelength-multiplexed diffractive network, where a unidirectional magnifier and a unidirectional demagnifier operate simultaneously in opposite directions, at two distinct illumination wavelengths. The efficacy of the P-D2NN architecture was also validated experimentally using monochromatic terahertz illumination, successfully matching our numerical simulations. P-D2NN offers a physics-inspired strategy for designing task-specific visual processors.

Advances in next-generation sequencing technology have enabled the high-throughput profiling of metagenomes and accelerated the microbiome study. Recently, there has been a rise in quantitative studies that aim to decipher the microbiome co-occurrence network and its underlying community structure based on metagenomic sequence data. Uncovering the complex microbiome community structure is essential to understanding the role of the microbiome in disease progression and susceptibility. Taxonomic abundance data generated from metagenomic sequencing technologies are high-dimensional and compositional, suffering from uneven sampling depth, over-dispersion, and zero-inflation. These characteristics often challenge the reliability of the current methods for microbiome community detection. To this end, we propose a Bayesian stochastic block model to study the microbiome co-occurrence network based on the recently developed modified centered-log ratio transformation tailored for microbiome data analysis. Our model allows us to incorporate taxonomic tree information using a Markov random field prior. The model parameters are jointly inferred by using Markov chain Monte Carlo sampling techniques. Our simulation study showed that the proposed approach performs better than competing methods even when taxonomic tree information is non-informative. We applied our approach to a real urinary microbiome dataset from postmenopausal women, the first time the urinary microbiome co-occurrence network structure has been studied. In summary, this statistical methodology provides a new tool for facilitating advanced microbiome studies.

Due to their intrinsic capabilities on parallel signal processing, optical neural networks (ONNs) have attracted extensive interests recently as a potential alternative to electronic artificial neural networks (ANNs) with reduced power consumption and low latency. Preliminary confirmation of the parallelism in optical computing has been widely done by applying the technology of wavelength division multiplexing (WDM) in the linear transformation part of neural networks. However, inter-channel crosstalk has obstructed WDM technologies to be deployed in nonlinear activation in ONNs. Here, we propose a universal WDM structure called multiplexed neuron sets (MNS) which apply WDM technologies to optical neurons and enable ONNs to be further compressed. A corresponding back-propagation (BP) training algorithm is proposed to alleviate or even cancel the influence of inter-channel crosstalk on MNS-based WDM-ONNs. For simplicity, semiconductor optical amplifiers (SOAs) are employed as an example of MNS to construct a WDM-ONN trained with the new algorithm. The result shows that the combination of MNS and the corresponding BP training algorithm significantly downsize the system and improve the energy efficiency to tens of times while giving similar performance to traditional ONNs.

Recently, data-driven models such as deep neural networks have shown to be promising tools for modelling and state inference in soft robots. However, voluminous amounts of data are necessary for deep models to perform effectively, which requires exhaustive and quality data collection, particularly of state labels. Consequently, obtaining labelled state data for soft robotic systems is challenged for various reasons, including difficulty in the sensorization of soft robots and the inconvenience of collecting data in unstructured environments. To address this challenge, in this paper, we propose a semi-supervised sequential variational Bayes (DSVB) framework for transfer learning and state inference in soft robots with missing state labels on certain robot configurations. Considering that soft robots may exhibit distinct dynamics under different robot configurations, a feature space transfer strategy is also incorporated to promote the adaptation of latent features across multiple configurations. Unlike existing transfer learning approaches, our proposed DSVB employs a recurrent neural network to model the nonlinear dynamics and temporal coherence in soft robot data. The proposed framework is validated on multiple setup configurations of a pneumatic-based soft robot finger. Experimental results on four transfer scenarios demonstrate that DSVB performs effective transfer learning and accurate state inference amidst missing state labels. The data and code are available at //github.com/shageenderan/DSVB.

The growing energy and performance costs of deep learning have driven the community to reduce the size of neural networks by selectively pruning components. Similarly to their biological counterparts, sparse networks generalize just as well, if not better than, the original dense networks. Sparsity can reduce the memory footprint of regular networks to fit mobile devices, as well as shorten training time for ever growing networks. In this paper, we survey prior work on sparsity in deep learning and provide an extensive tutorial of sparsification for both inference and training. We describe approaches to remove and add elements of neural networks, different training strategies to achieve model sparsity, and mechanisms to exploit sparsity in practice. Our work distills ideas from more than 300 research papers and provides guidance to practitioners who wish to utilize sparsity today, as well as to researchers whose goal is to push the frontier forward. We include the necessary background on mathematical methods in sparsification, describe phenomena such as early structure adaptation, the intricate relations between sparsity and the training process, and show techniques for achieving acceleration on real hardware. We also define a metric of pruned parameter efficiency that could serve as a baseline for comparison of different sparse networks. We close by speculating on how sparsity can improve future workloads and outline major open problems in the field.

Graph representation learning for hypergraphs can be used to extract patterns among higher-order interactions that are critically important in many real world problems. Current approaches designed for hypergraphs, however, are unable to handle different types of hypergraphs and are typically not generic for various learning tasks. Indeed, models that can predict variable-sized heterogeneous hyperedges have not been available. Here we develop a new self-attention based graph neural network called Hyper-SAGNN applicable to homogeneous and heterogeneous hypergraphs with variable hyperedge sizes. We perform extensive evaluations on multiple datasets, including four benchmark network datasets and two single-cell Hi-C datasets in genomics. We demonstrate that Hyper-SAGNN significantly outperforms the state-of-the-art methods on traditional tasks while also achieving great performance on a new task called outsider identification. Hyper-SAGNN will be useful for graph representation learning to uncover complex higher-order interactions in different applications.

Recent advances in 3D fully convolutional networks (FCN) have made it feasible to produce dense voxel-wise predictions of volumetric images. In this work, we show that a multi-class 3D FCN trained on manually labeled CT scans of several anatomical structures (ranging from the large organs to thin vessels) can achieve competitive segmentation results, while avoiding the need for handcrafting features or training class-specific models. To this end, we propose a two-stage, coarse-to-fine approach that will first use a 3D FCN to roughly define a candidate region, which will then be used as input to a second 3D FCN. This reduces the number of voxels the second FCN has to classify to ~10% and allows it to focus on more detailed segmentation of the organs and vessels. We utilize training and validation sets consisting of 331 clinical CT images and test our models on a completely unseen data collection acquired at a different hospital that includes 150 CT scans, targeting three anatomical organs (liver, spleen, and pancreas). In challenging organs such as the pancreas, our cascaded approach improves the mean Dice score from 68.5 to 82.2%, achieving the highest reported average score on this dataset. We compare with a 2D FCN method on a separate dataset of 240 CT scans with 18 classes and achieve a significantly higher performance in small organs and vessels. Furthermore, we explore fine-tuning our models to different datasets. Our experiments illustrate the promise and robustness of current 3D FCN based semantic segmentation of medical images, achieving state-of-the-art results. Our code and trained models are available for download: //github.com/holgerroth/3Dunet_abdomen_cascade.

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