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Medical image segmentation is a critical process in the field of medical imaging, playing a pivotal role in diagnosis, treatment, and research. It involves partitioning of an image into multiple regions, representing distinct anatomical or pathological structures. Conventional methods often grapple with the challenge of balancing spatial precision and comprehensive feature representation due to their reliance on traditional loss functions. To overcome this, we propose Feature-Enhanced Spatial Segmentation Loss (FESS Loss), that integrates the benefits of contrastive learning (which extracts intricate features, particularly in the nuanced domain of medical imaging) with the spatial accuracy inherent in the Dice loss. The objective is to augment both spatial precision and feature-based representation in the segmentation of medical images. FESS Loss signifies a notable advancement, offering a more accurate and refined segmentation process, ultimately contributing to heightened precision in the analysis of medical images. Further, FESS loss demonstrates superior performance in limited annotated data availability scenarios often present in the medical domain.

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Deformable image registration plays a crucial role in medical imaging, aiding in disease diagnosis and image-guided interventions. Traditional iterative methods are slow, while deep learning (DL) accelerates solutions but faces usability and precision challenges. This study introduces a pyramid network with the enhanced motion decomposition Transformer (ModeTv2) operator, showcasing superior pairwise optimization (PO) akin to traditional methods. We re-implement ModeT operator with CUDA extensions to enhance its computational efficiency. We further propose RegHead module which refines deformation fields, improves the realism of deformation and reduces parameters. By adopting the PO, the proposed network balances accuracy, efficiency, and generalizability. Extensive experiments on two public brain MRI datasets and one abdominal CT dataset demonstrate the network's suitability for PO, providing a DL model with enhanced usability and interpretability. The code is publicly available.

Medical image registration is vital for disease diagnosis and treatment with its ability to merge diverse information of images, which may be captured under different times, angles, or modalities. Although several surveys have reviewed the development of medical image registration, these surveys have not systematically summarized methodologies of existing medical image registration methods. To this end, we provide a comprehensive review of these methods from traditional and deep learning-based directions, aiming to help audiences understand the development of medical image registration quickly. In particular, we review recent advances in retinal image registration at the end of each section, which has not attracted much attention. Additionally, we also discuss the current challenges of retinal image registration and provide insights and prospects for future research.

Ultrasound imaging is crucial for evaluating organ morphology and function, yet depth adjustment can degrade image quality and field-of-view, presenting a depth-dependent dilemma. Traditional interpolation-based zoom-in techniques often sacrifice detail and introduce artifacts. Motivated by the potential of arbitrary-scale super-resolution to naturally address these inherent challenges, we present the Residual Dense Swin Transformer Network (RDSTN), designed to capture the non-local characteristics and long-range dependencies intrinsic to ultrasound images. It comprises a linear embedding module for feature enhancement, an encoder with shifted-window attention for modeling non-locality, and an MLP decoder for continuous detail reconstruction. This strategy streamlines balancing image quality and field-of-view, which offers superior textures over traditional methods. Experimentally, RDSTN outperforms existing approaches while requiring fewer parameters. In conclusion, RDSTN shows promising potential for ultrasound image enhancement by overcoming the limitations of conventional interpolation-based methods and achieving depth-independent imaging.

Curating annotations for medical image segmentation is a labor-intensive and time-consuming task that requires domain expertise, resulting in "narrowly" focused deep learning (DL) models with limited translational utility. Recently, foundation models like the Segment Anything Model (SAM) have revolutionized semantic segmentation with exceptional zero-shot generalizability across various domains, including medical imaging, and hold a lot of promise for streamlining the annotation process. However, SAM has yet to be evaluated in a crowd-sourced setting to curate annotations for training 3D DL segmentation models. In this work, we explore the potential of SAM for crowd-sourcing "sparse" annotations from non-experts to generate "dense" segmentation masks for training 3D nnU-Net models, a state-of-the-art DL segmentation model. Our results indicate that while SAM-generated annotations exhibit high mean Dice scores compared to ground-truth annotations, nnU-Net models trained on SAM-generated annotations perform significantly worse than nnU-Net models trained on ground-truth annotations ($p<0.001$, all).

In clinical applications that involve ultrasound-guided intervention, the visibility of the needle can be severely impeded due to steep insertion and strong distractors such as speckle noise and anatomical occlusion. To address this challenge, we propose VibNet, a learning-based framework tailored to enhance the robustness and accuracy of needle detection in ultrasound images, even when the target becomes invisible to the naked eye. Inspired by Eulerian Video Magnification techniques, we utilize an external step motor to induce low-amplitude periodic motion on the needle. These subtle vibrations offer the potential to generate robust frequency features for detecting the motion patterns around the needle. To robustly and precisely detect the needle leveraging these vibrations, VibNet integrates learning-based Short-Time-Fourier-Transform and Hough-Transform modules to achieve successive sub-goals, including motion feature extraction in the spatiotemporal space, frequency feature aggregation, and needle detection in the Hough space. Based on the results obtained on distinct ex vivo porcine and bovine tissue samples, the proposed algorithm exhibits superior detection performance with efficient computation and generalization capability.

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly difficult and costly to obtain especially in the medical imaging domain where only experts can provide reliable and accurate annotations. Semi-supervised learning has emerged as an appealing strategy and been widely applied to medical image segmentation tasks to train deep models with limited annotations. In this paper, we present a comprehensive review of recently proposed semi-supervised learning methods for medical image segmentation and summarized both the technical novelties and empirical results. Furthermore, we analyze and discuss the limitations and several unsolved problems of existing approaches. We hope this review could inspire the research community to explore solutions for this challenge and further promote the developments in medical image segmentation field.

Answering complex questions about images is an ambitious goal for machine intelligence, which requires a joint understanding of images, text, and commonsense knowledge, as well as a strong reasoning ability. Recently, multimodal Transformers have made great progress in the task of Visual Commonsense Reasoning (VCR), by jointly understanding visual objects and text tokens through layers of cross-modality attention. However, these approaches do not utilize the rich structure of the scene and the interactions between objects which are essential in answering complex commonsense questions. We propose a Scene Graph Enhanced Image-Text Learning (SGEITL) framework to incorporate visual scene graphs in commonsense reasoning. To exploit the scene graph structure, at the model structure level, we propose a multihop graph transformer for regularizing attention interaction among hops. As for pre-training, a scene-graph-aware pre-training method is proposed to leverage structure knowledge extracted in the visual scene graph. Moreover, we introduce a method to train and generate domain-relevant visual scene graphs using textual annotations in a weakly-supervised manner. Extensive experiments on VCR and other tasks show a significant performance boost compared with the state-of-the-art methods and prove the efficacy of each proposed component.

Applying artificial intelligence techniques in medical imaging is one of the most promising areas in medicine. However, most of the recent success in this area highly relies on large amounts of carefully annotated data, whereas annotating medical images is a costly process. In this paper, we propose a novel method, called FocalMix, which, to the best of our knowledge, is the first to leverage recent advances in semi-supervised learning (SSL) for 3D medical image detection. We conducted extensive experiments on two widely used datasets for lung nodule detection, LUNA16 and NLST. Results show that our proposed SSL methods can achieve a substantial improvement of up to 17.3% over state-of-the-art supervised learning approaches with 400 unlabeled CT scans.

Image segmentation is a key topic in image processing and computer vision with applications such as scene understanding, medical image analysis, robotic perception, video surveillance, augmented reality, and image compression, among many others. Various algorithms for image segmentation have been developed in the literature. Recently, due to the success of deep learning models in a wide range of vision applications, there has been a substantial amount of works aimed at developing image segmentation approaches using deep learning models. In this survey, we provide a comprehensive review of the literature at the time of this writing, covering a broad spectrum of pioneering works for semantic and instance-level segmentation, including fully convolutional pixel-labeling networks, encoder-decoder architectures, multi-scale and pyramid based approaches, recurrent networks, visual attention models, and generative models in adversarial settings. We investigate the similarity, strengths and challenges of these deep learning models, examine the most widely used datasets, report performances, and discuss promising future research directions in this area.

Image segmentation is considered to be one of the critical tasks in hyperspectral remote sensing image processing. Recently, convolutional neural network (CNN) has established itself as a powerful model in segmentation and classification by demonstrating excellent performances. The use of a graphical model such as a conditional random field (CRF) contributes further in capturing contextual information and thus improving the segmentation performance. In this paper, we propose a method to segment hyperspectral images by considering both spectral and spatial information via a combined framework consisting of CNN and CRF. We use multiple spectral cubes to learn deep features using CNN, and then formulate deep CRF with CNN-based unary and pairwise potential functions to effectively extract the semantic correlations between patches consisting of three-dimensional data cubes. Effective piecewise training is applied in order to avoid the computationally expensive iterative CRF inference. Furthermore, we introduce a deep deconvolution network that improves the segmentation masks. We also introduce a new dataset and experimented our proposed method on it along with several widely adopted benchmark datasets to evaluate the effectiveness of our method. By comparing our results with those from several state-of-the-art models, we show the promising potential of our method.

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