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Alzheimer's disease is a neurodegenerative condition that accelerates cognitive decline relative to normal aging. It is of critical scientific importance to gain a better understanding of early disease mechanisms in the brain to facilitate effective, targeted therapies. The volume of the hippocampus is often used in diagnosis and monitoring of the disease. Measuring this volume via neuroimaging is difficult since each hippocampus must either be manually identified or automatically delineated, a task referred to as segmentation. Automatic hippocampal segmentation often involves mapping a previously manually segmented image to a new brain image and propagating the labels to obtain an estimate of where each hippocampus is located in the new image. A more recent approach to this problem is to propagate labels from multiple manually segmented atlases and combine the results using a process known as label fusion. To date, most label fusion algorithms employ voting procedures with voting weights assigned directly or estimated via optimization. We propose using a fully Bayesian spatial regression model for label fusion that facilitates direct incorporation of covariate information while making accessible the entire posterior distribution. Our results suggest that incorporating tissue classification (e.g, gray matter) into the label fusion procedure can greatly improve segmentation when relatively homogeneous, healthy brains are used as atlases for diseased brains. The fully Bayesian approach also produces meaningful uncertainty measures about hippocampal volumes, information which can be leveraged to detect significant, scientifically meaningful differences between healthy and diseased populations, improving the potential for early detection and tracking of the disease.

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Attention mechanisms have significantly boosted the performance of video classification neural networks thanks to the utilization of perspective contexts. However, the current research on video attention generally focuses on adopting a specific aspect of contexts (e.g., channel, spatial/temporal, or global context) to refine the features and neglects their underlying correlation when computing attentions. This leads to incomplete context utilization and hence bears the weakness of limited performance improvement. To tackle the problem, this paper proposes an efficient attention-in-attention (AIA) method for element-wise feature refinement, which investigates the feasibility of inserting the channel context into the spatio-temporal attention learning module, referred to as CinST, and also its reverse variant, referred to as STinC. Specifically, we instantiate the video feature contexts as dynamics aggregated along a specific axis with global average and max pooling operations. The workflow of an AIA module is that the first attention block uses one kind of context information to guide the gating weights calculation of the second attention that targets at the other context. Moreover, all the computational operations in attention units act on the pooled dimension, which results in quite few computational cost increase ($<$0.02\%). To verify our method, we densely integrate it into two classical video network backbones and conduct extensive experiments on several standard video classification benchmarks. The source code of our AIA is available at \url{//github.com/haoyanbin918/Attention-in-Attention}.

Multimodal emotion recognition has recently gained much attention since it can leverage diverse and complementary relationships over multiple modalities (e.g., audio, visual, biosignals, etc.), and can provide some robustness to noisy modalities. Most state-of-the-art methods for audio-visual (A-V) fusion rely on recurrent networks or conventional attention mechanisms that do not effectively leverage the complementary nature of A-V modalities. In this paper, we focus on dimensional emotion recognition based on the fusion of facial and vocal modalities extracted from videos. Specifically, we propose a joint cross-attention model that relies on the complementary relationships to extract the salient features across A-V modalities, allowing for accurate prediction of continuous values of valence and arousal. The proposed fusion model efficiently leverages the inter-modal relationships, while reducing the heterogeneity between the features. In particular, it computes the cross-attention weights based on correlation between the combined feature representation and individual modalities. By deploying the combined A-V feature representation into the cross-attention module, the performance of our fusion module improves significantly over the vanilla cross-attention module. Experimental results on validation-set videos from the AffWild2 dataset indicate that our proposed A-V fusion model provides a cost-effective solution that can outperform state-of-the-art approaches. The code is available on GitHub: //github.com/praveena2j/JointCrossAttentional-AV-Fusion.

In this paper we present a deep learning method to predict the temporal evolution of dissipative dynamic systems. We propose using both geometric and thermodynamic inductive biases to improve accuracy and generalization of the resulting integration scheme. The first is achieved with Graph Neural Networks, which induces a non-Euclidean geometrical prior with permutation invariant node and edge update functions. The second bias is forced by learning the GENERIC structure of the problem, an extension of the Hamiltonian formalism, to model more general non-conservative dynamics. Several examples are provided in both Eulerian and Lagrangian description in the context of fluid and solid mechanics respectively, achieving relative mean errors of less than 3% in all the tested examples. Two ablation studies are provided based on recent works in both physics-informed and geometric deep learning.

Data collection and research methodology represents a critical part of the research pipeline. On the one hand, it is important that we collect data in a way that maximises the validity of what we are measuring, which may involve the use of long scales with many items. On the other hand, collecting a large number of items across multiple scales results in participant fatigue, and expensive and time consuming data collection. It is therefore important that we use the available resources optimally. In this work, we consider how a consideration for theory and the associated causal/structural model can help us to streamline data collection procedures by not wasting time collecting data for variables which are not causally critical for subsequent analysis. This not only saves time and enables us to redirect resources to attend to other variables which are more important, but also increases research transparency and the reliability of theory testing. In order to achieve this streamlined data collection, we leverage structural models, and Markov conditional independency structures implicit in these models to identify the substructures which are critical for answering a particular research question. In this work, we review the relevant concepts and present a number of didactic examples with the hope that psychologists can use these techniques to streamline their data collection process without invalidating the subsequent analysis. We provide a number of simulation results to demonstrate the limited analytical impact of this streamlining.

We investigate the feature compression of high-dimensional ridge regression using the optimal subsampling technique. Specifically, based on the basic framework of random sampling algorithm on feature for ridge regression and the A-optimal design criterion, we first obtain a set of optimal subsampling probabilities. Considering that the obtained probabilities are uneconomical, we then propose the nearly optimal ones. With these probabilities, a two step iterative algorithm is established which has lower computational cost and higher accuracy. We provide theoretical analysis and numerical experiments to support the proposed methods. Numerical results demonstrate the decent performance of our methods.

In this paper, we introduce reduced-bias estimators for the estimation of the tail index of a Pareto-type distribution. This is achieved through the use of a regularised weighted least squares with an exponential regression model for log-spacings of top order statistics. The asymptotic properties of the proposed estimators are investigated analytically and found to be asymptotically unbiased, consistent and normally distributed. Also, the finite sample behaviour of the estimators are studied through a simulations theory. The proposed estimators were found to yield low bias and MSE. In addition, the proposed estimators are illustrated through the estimation of the tail index of the underlying distribution of claims from the insurance industry.

Super-Resolution is the process of generating a high-resolution image from a low-resolution image. A picture may be of lower resolution due to smaller spatial resolution, poor camera quality, as a result of blurring, or due to other possible degradations. Super-Resolution is the technique to improve the quality of a low-resolution photo by boosting its plausible resolution. The computer vision community has extensively explored the area of Super-Resolution. However, the previous Super-Resolution methods require vast amounts of data for training. This becomes problematic in domains where very few low-resolution, high-resolution pairs might be available. One of such areas is statistical downscaling, where super-resolution is increasingly being used to obtain high-resolution climate information from low-resolution data. Acquiring high-resolution climate data is extremely expensive and challenging. To reduce the cost of generating high-resolution climate information, Super-Resolution algorithms should be able to train with a limited number of low-resolution, high-resolution pairs. This paper tries to solve the aforementioned problem by introducing a semi-supervised way to perform super-resolution that can generate sharp, high-resolution images with as few as 500 paired examples. The proposed semi-supervised technique can be used as a plug-and-play module with any supervised GAN-based Super-Resolution method to enhance its performance. We quantitatively and qualitatively analyze the performance of the proposed model and compare it with completely supervised methods as well as other unsupervised techniques. Comprehensive evaluations show the superiority of our method over other methods on different metrics. We also offer the applicability of our approach in statistical downscaling to obtain high-resolution climate images.

Humans perceive the world by concurrently processing and fusing high-dimensional inputs from multiple modalities such as vision and audio. Machine perception models, in stark contrast, are typically modality-specific and optimised for unimodal benchmarks, and hence late-stage fusion of final representations or predictions from each modality (`late-fusion') is still a dominant paradigm for multimodal video classification. Instead, we introduce a novel transformer based architecture that uses `fusion bottlenecks' for modality fusion at multiple layers. Compared to traditional pairwise self-attention, our model forces information between different modalities to pass through a small number of bottleneck latents, requiring the model to collate and condense the most relevant information in each modality and only share what is necessary. We find that such a strategy improves fusion performance, at the same time reducing computational cost. We conduct thorough ablation studies, and achieve state-of-the-art results on multiple audio-visual classification benchmarks including Audioset, Epic-Kitchens and VGGSound. All code and models will be released.

Knowledge graph completion aims to predict missing relations between entities in a knowledge graph. While many different methods have been proposed, there is a lack of a unifying framework that would lead to state-of-the-art results. Here we develop PathCon, a knowledge graph completion method that harnesses four novel insights to outperform existing methods. PathCon predicts relations between a pair of entities by: (1) Considering the Relational Context of each entity by capturing the relation types adjacent to the entity and modeled through a novel edge-based message passing scheme; (2) Considering the Relational Paths capturing all paths between the two entities; And, (3) adaptively integrating the Relational Context and Relational Path through a learnable attention mechanism. Importantly, (4) in contrast to conventional node-based representations, PathCon represents context and path only using the relation types, which makes it applicable in an inductive setting. Experimental results on knowledge graph benchmarks as well as our newly proposed dataset show that PathCon outperforms state-of-the-art knowledge graph completion methods by a large margin. Finally, PathCon is able to provide interpretable explanations by identifying relations that provide the context and paths that are important for a given predicted relation.

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