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Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal imaging data of optical coherence tomography (OCT). To address the data scarcity issue, this paper proposes two solutions. First, we develop a novel generalization-reinforced semi-supervised learning (SSL) model called pseudo supervisor to optimally utilize unlabeled data. Compared with SOTA models, the proposed pseudo supervisor optimizes the policy of predicting pseudo labels with unlabeled samples to improve empirical generalization. Our pseudo supervisor model is evaluated with two clinical tasks consisting of glaucoma detection and progression forecasting. The progression forecasting task is evaluated both unimodally and multimodally. Our pseudo supervisor model demonstrates superior performance than SOTA SSL comparison models. Moreover, our model also achieves the best results on the publicly available LAG fundus dataset. Second, we introduce the Harvard Glaucoma Detection and Progression (Harvard-GDP) Dataset, a multimodal multitask dataset that includes data from 1,000 patients with OCT imaging data, as well as labels for glaucoma detection and progression. This is the largest glaucoma detection dataset with 3D OCT imaging data and the first glaucoma progression forecasting dataset that is publicly available. Detailed sex and racial analysis are provided, which can be used by interested researchers for fairness learning studies. Our released dataset is benchmarked with several SOTA supervised CNN and transformer deep learning models. The dataset and code are made publicly available via \url{//ophai.hms.harvard.edu/datasets/harvard-gdp1000}.

Structural re-parameterization is a general training scheme for Convolutional Neural Networks (CNNs), which achieves performance improvement without increasing inference cost. As Vision Transformers (ViTs) are gradually surpassing CNNs in various visual tasks, one may question: if a training scheme specifically for ViTs exists that can also achieve performance improvement without increasing inference cost? Recently, Mixture-of-Experts (MoE) has attracted increasing attention, as it can efficiently scale up the capacity of Transformers at a fixed cost through sparsely activated experts. Considering that MoE can also be viewed as a multi-branch structure, can we utilize MoE to implement a ViT training scheme similar to structural re-parameterization? In this paper, we affirmatively answer these questions, with a new general training strategy for ViTs. Specifically, we decouple the training and inference phases of ViTs. During training, we replace some Feed-Forward Networks (FFNs) of the ViT with specially designed, more efficient MoEs that assign tokens to experts by random uniform partition, and perform Experts Weights Averaging (EWA) on these MoEs at the end of each iteration. After training, we convert each MoE into an FFN by averaging the experts, transforming the model back into original ViT for inference. We further provide a theoretical analysis to show why and how it works. Comprehensive experiments across various 2D and 3D visual tasks, ViT architectures, and datasets validate the effectiveness and generalizability of the proposed training scheme. Besides, our training scheme can also be applied to improve performance when fine-tuning ViTs. Lastly, but equally important, the proposed EWA technique can significantly improve the effectiveness of naive MoE in various 2D visual small datasets and 3D visual tasks.

In learning-to-rank (LTR), optimizing only the relevance (or the expected ranking utility) can cause representational harm to certain categories of items. Moreover, if there is implicit bias in the relevance scores, LTR models may fail to optimize for true relevance. Previous works have proposed efficient algorithms to train stochastic ranking models that achieve fairness of exposure to the groups ex-ante (or, in expectation), which may not guarantee representation fairness to the groups ex-post, that is, after realizing a ranking from the stochastic ranking model. Typically, ex-post fairness is achieved by post-processing, but previous work does not train stochastic ranking models that are aware of this post-processing. In this paper, we propose a novel objective that maximizes expected relevance only over those rankings that satisfy given representation constraints to ensure ex-post fairness. Building upon recent work on an efficient sampler for ex-post group-fair rankings, we propose a group-fair Plackett-Luce model and show that it can be efficiently optimized for our objective in the LTR framework. Experiments on three real-world datasets show that our group-fair algorithm guarantees fairness alongside usually having better relevance compared to the LTR baselines. In addition, our algorithm also achieves better relevance than post-processing baselines, which also ensures ex-post fairness. Further, when implicit bias is injected into the training data, our algorithm typically outperforms existing LTR baselines in relevance.

Multivariate Time Series (MVTS) anomaly detection is a long-standing and challenging research topic that has attracted tremendous research effort from both industry and academia recently. However, a careful study of the literature makes us realize that 1) the community is active but not as organized as other sibling machine learning communities such as Computer Vision (CV) and Natural Language Processing (NLP), and 2) most proposed solutions are evaluated using either inappropriate or highly flawed protocols, with an apparent lack of scientific foundation. So flawed is one very popular protocol, the so-called \pa protocol, that a random guess can be shown to systematically outperform \emph{all} algorithms developed so far. In this paper, we review and evaluate many recent algorithms using more robust protocols and discuss how a normally good protocol may have weaknesses in the context of MVTS anomaly detection and how to mitigate them. We also share our concerns about benchmark datasets, experiment design and evaluation methodology we observe in many works. Furthermore, we propose a simple, yet challenging, baseline algorithm based on Principal Components Analysis (PCA) that surprisingly outperforms many recent Deep Learning (DL) based approaches on popular benchmark datasets. The main objective of this work is to stimulate more effort towards important aspects of the research such as data, experiment design, evaluation methodology and result interpretability, instead of putting the highest weight on the design of increasingly more complex and "fancier" algorithms.

Existing K-nearest neighbor (KNN) retrieval-based methods usually conduct industrial anomaly detection in two stages: obtain feature representations with a pre-trained CNN model and perform distance measures for defect detection. However, the features are not fully exploited as they ignore domain bias and the difference of local density in feature space, which limits the detection performance. In this paper, we propose Reducing Biases (REB) in representation by considering the domain bias of the pre-trained model and building a self-supervised learning task for better domain adaption with a defect generation strategy (DefectMaker) imitating the natural defects. Additionally, we propose a local density KNN (LDKNN) to reduce the local density bias and obtain effective anomaly detection. We achieve a promising result of 99.5\% AUROC on the widely used MVTec AD benchmark. We also achieve 88.0\% AUROC on the challenging MVTec LOCO AD dataset and bring an improvement of 4.7\% AUROC to the state-of-the-art result. All results are obtained with smaller backbone networks such as Vgg11 and Resnet18, which indicates the effectiveness and efficiency of REB for practical industrial applications.

Computerized Adaptive Testing (CAT) is a widely used, efficient test mode that adapts to the examinee's proficiency level in the test domain. CAT requires pre-trained item profiles, for CAT iteratively assesses the student real-time based on the registered items' profiles, and selects the next item to administer using candidate items' profiles. However, obtaining such item profiles is a costly process that involves gathering a large, dense item-response data, then training a diagnostic model on the collected data. In this paper, we explore the possibility of leveraging response data collected in the CAT service. We first show that this poses a unique challenge due to the inherent selection bias introduced by CAT, i.e., more proficient students will receive harder questions. Indeed, when naively training the diagnostic model using CAT response data, we observe that item profiles deviate significantly from the ground-truth. To tackle the selection bias issue, we propose the user-wise aggregate influence function method. Our intuition is to filter out users whose response data is heavily biased in an aggregate manner, as judged by how much perturbation the added data will introduce during parameter estimation. This way, we may enhance the performance of CAT while introducing minimal bias to the item profiles. We provide extensive experiments to demonstrate the superiority of our proposed method based on the three public datasets and one dataset that contains real-world CAT response data.

Large Language Models (LLMs) have revolutionized Natural Language Processing (NLP). Although convenient for research and practical applications, open-source LLMs with fewer parameters often suffer from severe hallucinations compared to their larger counterparts. This paper focuses on measuring and reducing hallucinations in BLOOM 7B, a representative of such weaker open-source LLMs that are publicly available for research and commercial applications. We introduce HaloCheck, a lightweight BlackBox knowledge-free framework designed to quantify the severity of hallucinations in LLMs. Additionally, we explore techniques like knowledge injection and teacher-student approaches to alleviate hallucinations in low-parameter LLMs. Our experiments effectively demonstrate the reduction of hallucinations in challenging domains for these LLMs.

Pre-trained Language Models (PLMs) have achieved great success in various Natural Language Processing (NLP) tasks under the pre-training and fine-tuning paradigm. With large quantities of parameters, PLMs are computation-intensive and resource-hungry. Hence, model pruning has been introduced to compress large-scale PLMs. However, most prior approaches only consider task-specific knowledge towards downstream tasks, but ignore the essential task-agnostic knowledge during pruning, which may cause catastrophic forgetting problem and lead to poor generalization ability. To maintain both task-agnostic and task-specific knowledge in our pruned model, we propose ContrAstive Pruning (CAP) under the paradigm of pre-training and fine-tuning. It is designed as a general framework, compatible with both structured and unstructured pruning. Unified in contrastive learning, CAP enables the pruned model to learn from the pre-trained model for task-agnostic knowledge, and fine-tuned model for task-specific knowledge. Besides, to better retain the performance of the pruned model, the snapshots (i.e., the intermediate models at each pruning iteration) also serve as effective supervisions for pruning. Our extensive experiments show that adopting CAP consistently yields significant improvements, especially in extremely high sparsity scenarios. With only 3% model parameters reserved (i.e., 97% sparsity), CAP successfully achieves 99.2% and 96.3% of the original BERT performance in QQP and MNLI tasks. In addition, our probing experiments demonstrate that the model pruned by CAP tends to achieve better generalization ability.

We propose UniViLM: a Unified Video and Language pre-training Model for multimodal understanding and generation. Motivated by the recent success of BERT based pre-training technique for NLP and image-language tasks, VideoBERT and CBT are proposed to exploit BERT model for video and language pre-training using narrated instructional videos. Different from their works which only pre-train understanding task, we propose a unified video-language pre-training model for both understanding and generation tasks. Our model comprises of 4 components including two single-modal encoders, a cross encoder and a decoder with the Transformer backbone. We first pre-train our model to learn the universal representation for both video and language on a large instructional video dataset. Then we fine-tune the model on two multimodal tasks including understanding task (text-based video retrieval) and generation task (multimodal video captioning). Our extensive experiments show that our method can improve the performance of both understanding and generation tasks and achieves the state-of-the art results.

State-of-the-art Convolutional Neural Network (CNN) benefits a lot from multi-task learning (MTL), which learns multiple related tasks simultaneously to obtain shared or mutually related representations for different tasks. The most widely-used MTL CNN structure is based on an empirical or heuristic split on a specific layer (e.g., the last convolutional layer) to minimize different task-specific losses. However, this heuristic sharing/splitting strategy may be harmful to the final performance of one or multiple tasks. In this paper, we propose a novel CNN structure for MTL, which enables automatic feature fusing at every layer. Specifically, we first concatenate features from different tasks according to their channel dimension, and then formulate the feature fusing problem as discriminative dimensionality reduction. We show that this discriminative dimensionality reduction can be done by 1x1 Convolution, Batch Normalization, and Weight Decay in one CNN, which we refer to as Neural Discriminative Dimensionality Reduction (NDDR). We perform ablation analysis in details for different configurations in training the network. The experiments carried out on different network structures and different task sets demonstrate the promising performance and desirable generalizability of our proposed method.