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The advancement of Internet and Communication Technologies (ICTs) has led to the era of Industry 4.0. This shift is followed by healthcare industries creating the term Healthcare 4.0. In Healthcare 4.0, the use of IoT-enabled medical imaging devices for early disease detection has enabled medical practitioners to increase healthcare institutions' quality of service. However, Healthcare 4.0 is still lagging in Artificial Intelligence and big data compared to other Industry 4.0 due to data privacy concerns. In addition, institutions' diverse storage and computing capabilities restrict institutions from incorporating the same training model structure. This paper presents a secure multi-party computation-based ensemble federated learning with blockchain that enables heterogeneous models to collaboratively learn from healthcare institutions' data without violating users' privacy. Blockchain properties also allow the party to enjoy data integrity without trust in a centralized server while also providing each healthcare institution with auditability and version control capability.

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The proliferation of deep learning applications in healthcare calls for data aggregation across various institutions, a practice often associated with significant privacy concerns. This concern intensifies in medical image analysis, where privacy-preserving mechanisms are paramount due to the data being sensitive in nature. Federated learning, which enables cooperative model training without direct data exchange, presents a promising solution. Nevertheless, the inherent vulnerabilities of federated learning necessitate further privacy safeguards. This study addresses this need by integrating differential privacy, a leading privacy-preserving technique, into a federated learning framework for medical image classification. We introduce a novel differentially private federated learning model and meticulously examine its impacts on privacy preservation and model performance. Our research confirms the existence of a trade-off between model accuracy and privacy settings. However, we demonstrate that strategic calibration of the privacy budget in differential privacy can uphold robust image classification performance while providing substantial privacy protection.

Probabilistic counters are well-known tools often used for space-efficient set cardinality estimation. In this paper, we investigate probabilistic counters from the perspective of preserving privacy. We use the standard, rigid differential privacy notion. The intuition is that the probabilistic counters do not reveal too much information about individuals but provide only general information about the population. Therefore, they can be used safely without violating the privacy of individuals. However, it turned out, that providing a precise, formal analysis of the privacy parameters of probabilistic counters is surprisingly difficult and needs advanced techniques and a very careful approach. We demonstrate that probabilistic counters can be used as a privacy protection mechanism without extra randomization. Namely, the inherent randomization from the protocol is sufficient for protecting privacy, even if the probabilistic counter is used multiple times. In particular, we present a specific privacy-preserving data aggregation protocol based on Morris Counter and MaxGeo Counter. Some of the presented results are devoted to counters that have not been investigated so far from the perspective of privacy protection. Another part is an improvement of previous results. We show how our results can be used to perform distributed surveys and compare the properties of counter-based solutions and a standard Laplace method.

Federated learning is a decentralized machine learning paradigm that allows multiple clients to collaborate by leveraging local computational power and the models transmission. This method reduces the costs and privacy concerns associated with centralized machine learning methods while ensuring data privacy by distributing training data across heterogeneous devices. On the other hand, federated learning has the drawback of data leakage due to the lack of privacy-preserving mechanisms employed during storage, transfer, and sharing, thus posing significant risks to data owners and suppliers. Blockchain technology has emerged as a promising technology for offering secure data-sharing platforms in federated learning, especially in Industrial Internet of Things (IIoT) settings. This survey aims to compare the performance and security of various data privacy mechanisms adopted in blockchain-based federated learning architectures. We conduct a systematic review of existing literature on secure data-sharing platforms for federated learning provided by blockchain technology, providing an in-depth overview of blockchain-based federated learning, its essential components, and discussing its principles, and potential applications. The primary contribution of this survey paper is to identify critical research questions and propose potential directions for future research in blockchain-based federated learning.

The popularization of intelligent healthcare devices and big data analytics significantly boosts the development of smart healthcare networks (SHNs). To enhance the precision of diagnosis, different participants in SHNs share health data that contains sensitive information. Therefore, the data exchange process raises privacy concerns, especially when the integration of health data from multiple sources (linkage attack) results in further leakage. Linkage attack is a type of dominant attack in the privacy domain, which can leverage various data sources for private data mining. Furthermore, adversaries launch poisoning attacks to falsify the health data, which leads to misdiagnosing or even physical damage. To protect private health data, we propose a personalized differential privacy model based on the trust levels among users. The trust is evaluated by a defined community density, while the corresponding privacy protection level is mapped to controllable randomized noise constrained by differential privacy. To avoid linkage attacks in personalized differential privacy, we designed a noise correlation decoupling mechanism using a Markov stochastic process. In addition, we build the community model on a blockchain, which can mitigate the risk of poisoning attacks during differentially private data transmission over SHNs. To testify the effectiveness and superiority of the proposed approach, we conduct extensive experiments on benchmark datasets.

Electronic Health Records (EHRs) have undergone numerous technical improvements in recent years, including the incorporation of mobile devices with the cloud computing technologies to facilitate medical data exchanges between patients and the healthcare professionals. This cutting-edge architecture enables cyber physical systems housed in the cloud to provide healthcare services with minimal operational costs, high flexibility, security, and EHR accessibility. If patient health information is stored in the hospital database, there will always be a risk of intrusion, i.e., unauthorized file access and information modification by attackers. To address this concern, we propose a decentralized EHR system based on Blockchain technology. To facilitate secure EHR exchange across various patients and medical providers, we develop a reliable access control method based on smart contracts. We incorporate Cryptocurrency, specifically Ethereum, in the suggested system to protect sensitive health information from potential attackers. In our suggested approach, both physicians and patients are required to be authenticated. Patients can register, and a block with a unique hash value will be generated. Once the patient discusses the disease with the physician, the physician can check the patient's condition and offer drugs. For experimental findings, we employ the public Block chain Ganache and solidity remix-based smart contracts to protect privacy. Ethers are used as the crypto currencies.

Artificial intelligence (AI) and deep learning techniques have gained significant attraction in recent years, owing to their remarkable capability of achieving high performance across a broad range of applications. However, a crucial challenge in training such models is the acquisition of vast amounts of data, which is often limited in fields like healthcare. In this domain, medical data is typically scattered across various sources such as hospitals, clinics, and wearable devices. The aggregated data collected from multiple sources in the healthcare domain is sufficient for training advanced deep learning models. However, these sources are frequently hesitant to share such data due to privacy considerations. To address this challenge, researchers have proposed the integration of blockchain and federated learning to develop a system that facilitates the secure sharing of medical records. This work provides a succinct review of the current state of the art in the use of blockchain and federated learning in the decentralized healthcare domain.

The existence of representative datasets is a prerequisite of many successful artificial intelligence and machine learning models. However, the subsequent application of these models often involves scenarios that are inadequately represented in the data used for training. The reasons for this are manifold and range from time and cost constraints to ethical considerations. As a consequence, the reliable use of these models, especially in safety-critical applications, is a huge challenge. Leveraging additional, already existing sources of knowledge is key to overcome the limitations of purely data-driven approaches, and eventually to increase the generalization capability of these models. Furthermore, predictions that conform with knowledge are crucial for making trustworthy and safe decisions even in underrepresented scenarios. This work provides an overview of existing techniques and methods in the literature that combine data-based models with existing knowledge. The identified approaches are structured according to the categories integration, extraction and conformity. Special attention is given to applications in the field of autonomous driving.

Autonomous driving has achieved a significant milestone in research and development over the last decade. There is increasing interest in the field as the deployment of self-operating vehicles on roads promises safer and more ecologically friendly transportation systems. With the rise of computationally powerful artificial intelligence (AI) techniques, autonomous vehicles can sense their environment with high precision, make safe real-time decisions, and operate more reliably without human interventions. However, intelligent decision-making in autonomous cars is not generally understandable by humans in the current state of the art, and such deficiency hinders this technology from being socially acceptable. Hence, aside from making safe real-time decisions, the AI systems of autonomous vehicles also need to explain how these decisions are constructed in order to be regulatory compliant across many jurisdictions. Our study sheds a comprehensive light on developing explainable artificial intelligence (XAI) approaches for autonomous vehicles. In particular, we make the following contributions. First, we provide a thorough overview of the present gaps with respect to explanations in the state-of-the-art autonomous vehicle industry. We then show the taxonomy of explanations and explanation receivers in this field. Thirdly, we propose a framework for an architecture of end-to-end autonomous driving systems and justify the role of XAI in both debugging and regulating such systems. Finally, as future research directions, we provide a field guide on XAI approaches for autonomous driving that can improve operational safety and transparency towards achieving public approval by regulators, manufacturers, and all engaged stakeholders.

The recent advancements in artificial intelligence (AI) combined with the extensive amount of data generated by today's clinical systems, has led to the development of imaging AI solutions across the whole value chain of medical imaging, including image reconstruction, medical image segmentation, image-based diagnosis and treatment planning. Notwithstanding the successes and future potential of AI in medical imaging, many stakeholders are concerned of the potential risks and ethical implications of imaging AI solutions, which are perceived as complex, opaque, and difficult to comprehend, utilise, and trust in critical clinical applications. Despite these concerns and risks, there are currently no concrete guidelines and best practices for guiding future AI developments in medical imaging towards increased trust, safety and adoption. To bridge this gap, this paper introduces a careful selection of guiding principles drawn from the accumulated experiences, consensus, and best practices from five large European projects on AI in Health Imaging. These guiding principles are named FUTURE-AI and its building blocks consist of (i) Fairness, (ii) Universality, (iii) Traceability, (iv) Usability, (v) Robustness and (vi) Explainability. In a step-by-step approach, these guidelines are further translated into a framework of concrete recommendations for specifying, developing, evaluating, and deploying technically, clinically and ethically trustworthy AI solutions into clinical practice.

As data are increasingly being stored in different silos and societies becoming more aware of data privacy issues, the traditional centralized training of artificial intelligence (AI) models is facing efficiency and privacy challenges. Recently, federated learning (FL) has emerged as an alternative solution and continue to thrive in this new reality. Existing FL protocol design has been shown to be vulnerable to adversaries within or outside of the system, compromising data privacy and system robustness. Besides training powerful global models, it is of paramount importance to design FL systems that have privacy guarantees and are resistant to different types of adversaries. In this paper, we conduct the first comprehensive survey on this topic. Through a concise introduction to the concept of FL, and a unique taxonomy covering: 1) threat models; 2) poisoning attacks and defenses against robustness; 3) inference attacks and defenses against privacy, we provide an accessible review of this important topic. We highlight the intuitions, key techniques as well as fundamental assumptions adopted by various attacks and defenses. Finally, we discuss promising future research directions towards robust and privacy-preserving federated learning.

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