Motion capture from a limited number of inertial measurement units (IMUs) has important applications in health, human performance, and virtual reality. Real-world limitations and application-specific goals dictate different IMU configurations (i.e., number of IMUs and chosen attachment body segments), trading off accuracy and practicality. Although recent works were successful in accurately reconstructing whole-body motion from six IMUs, these systems only work with a specific IMU configuration. Here we propose a single diffusion generative model, Diffusion Inertial Poser (DiffIP), which reconstructs human motion in real-time from arbitrary IMU configurations. We show that DiffIP has the benefit of flexibility with respect to the IMU configuration while being as accurate as the state-of-the-art for the commonly used six IMU configuration. Our system enables selecting an optimal configuration for different applications without retraining the model. For example, when only four IMUs are available, DiffIP found that the configuration that minimizes errors in joint kinematics instruments the thighs and forearms. However, global translation reconstruction is better when instrumenting the feet instead of the thighs. Although our approach is agnostic to the underlying model, we built DiffIP based on physiologically realistic musculoskeletal models to enable use in biomedical research and health applications.
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ACM/IEEE第23屆模型驅動工程語言和系統國際會議，是模型驅動軟件和系統工程的首要會議系列，由ACM-SIGSOFT和IEEE-TCSE支持組織。自1998年以來，模型涵蓋了建模的各個方面，從語言和方法到工具和應用程序。模特的參加者來自不同的背景，包括研究人員、學者、工程師和工業專業人士。MODELS 2019是一個論壇，參與者可以圍繞建模和模型驅動的軟件和系統交流前沿研究成果和創新實踐經驗。今年的版本將為建模社區提供進一步推進建模基礎的機會，并在網絡物理系統、嵌入式系統、社會技術系統、云計算、大數據、機器學習、安全、開源等新興領域提出建模的創新應用以及可持續性。
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Accurate prediction of Drug-Target Affinity (DTA) is of vital importance in early-stage drug discovery, facilitating the identification of drugs that can effectively interact with specific targets and regulate their activities. While wet experiments remain the most reliable method, they are time-consuming and resource-intensive, resulting in limited data availability that poses challenges for deep learning approaches. Existing methods have primarily focused on developing techniques based on the available DTA data, without adequately addressing the data scarcity issue. To overcome this challenge, we present the SSM-DTA framework, which incorporates three simple yet highly effective strategies: (1) A multi-task training approach that combines DTA prediction with masked language modeling (MLM) using paired drug-target data. (2) A semi-supervised training method that leverages large-scale unpaired molecules and proteins to enhance drug and target representations. This approach differs from previous methods that only employed molecules or proteins in pre-training. (3) The integration of a lightweight cross-attention module to improve the interaction between drugs and targets, further enhancing prediction accuracy. Through extensive experiments on benchmark datasets such as BindingDB, DAVIS, and KIBA, we demonstrate the superior performance of our framework. Additionally, we conduct case studies on specific drug-target binding activities, virtual screening experiments, drug feature visualizations, and real-world applications, all of which showcase the significant potential of our work. In conclusion, our proposed SSM-DTA framework addresses the data limitation challenge in DTA prediction and yields promising results, paving the way for more efficient and accurate drug discovery processes. Our code is available at $\href{//github.com/QizhiPei/SSM-DTA}{Github}$.
Recent research has explored the implementation of privacy-preserving deep neural networks solely using fully homomorphic encryption. However, its practicality has been limited because of prolonged inference times. When using a pre-trained model without retraining, a major factor contributing to these prolonged inference times is the high-degree polynomial approximation of activation functions such as the ReLU function. The high-degree approximation consumes a substantial amount of homomorphic computational resources, resulting in slower inference. Unlike the previous works approximating activation functions uniformly and conservatively, this paper presents a \emph{layerwise} degree optimization of activation functions to aggressively reduce the inference time while maintaining classification accuracy by taking into account the characteristics of each layer. Instead of the minimax approximation commonly used in state-of-the-art private inference models, we employ the weighted least squares approximation method with the input distributions of activation functions. Then, we obtain the layerwise optimized degrees for activation functions through the \emph{dynamic programming} algorithm, considering how each layer's approximation error affects the classification accuracy of the deep neural network. Furthermore, we propose modulating the ciphertext moduli-chain layerwise to reduce the inference time. By these proposed layerwise optimization methods, we can reduce inference times for the ResNet-20 model and the ResNet-32 model by 3.44 times and 3.16 times, respectively, in comparison to the prior implementations employing uniform degree polynomials and a consistent ciphertext modulus.
Advancements in deep neural networks have allowed automatic speech recognition (ASR) systems to attain human parity on several publicly available clean speech datasets. However, even state-of-the-art ASR systems experience performance degradation when confronted with adverse conditions, as a well-trained acoustic model is sensitive to variations in the speech domain, e.g., background noise. Intuitively, humans address this issue by relying on their linguistic knowledge: the meaning of ambiguous spoken terms is usually inferred from contextual cues thereby reducing the dependency on the auditory system. Inspired by this observation, we introduce the first open-source benchmark to utilize external large language models (LLMs) for ASR error correction, where N-best decoding hypotheses provide informative elements for true transcription prediction. This approach is a paradigm shift from the traditional language model rescoring strategy that can only select one candidate hypothesis as the output transcription. The proposed benchmark contains a novel dataset, HyPoradise (HP), encompassing more than 334,000 pairs of N-best hypotheses and corresponding accurate transcriptions across prevalent speech domains. Given this dataset, we examine three types of error correction techniques based on LLMs with varying amounts of labeled hypotheses-transcription pairs, which gains a significant word error rate (WER) reduction. Experimental evidence demonstrates the proposed technique achieves a breakthrough by surpassing the upper bound of traditional re-ranking based methods. More surprisingly, LLM with reasonable prompt and its generative capability can even correct those tokens that are missing in N-best list. We make our results publicly accessible for reproducible pipelines with released pre-trained models, thus providing a new evaluation paradigm for ASR error correction with LLMs.
Over the past few years, the division of gait phases has emerged as a complex area of research that carries significant importance for various applications in the field of gait technologies. The accurate partitioning of gait phases plays a crucial role in advancing these applications. Researchers have been exploring a range of sensors that can be employed to provide data for algorithms involved in gait phase partitioning. These sensors can be broadly categorized into two types: wearable and non-wearable, each offering unique advantages and capabilities. In our study aimed at examining the current approaches to gait analysis and detection specifically designed for implementation in ambulatory rehabilitation systems, we conducted a comprehensive meta-analysis of existing research studies. Our analysis revealed a diverse range of sensors and sensor combinations that demonstrate the ability to analyze gait patterns in ambulatory settings. These sensor options vary from basic force-based binary switches to more intricate setups incorporating multiple inertial sensors and sophisticated algorithms. The findings highlight the wide spectrum of available technologies and methodologies used in gait analysis for ambulatory applications. To conduct an extensive review, we systematically examined two prominent databases, IEEE and Scopus, with the aim of identifying relevant studies pertaining to gait analysis. The search criteria were limited to 189 papers published between 1999 and 2023. From this pool, we identified and included five papers that specifically focused on various techniques including Thresholding, Quasi-static method, adaptive classifier, and SVM-based approaches. These selected papers provided valuable insights for our review.
In healthcare, the role of AI is continually evolving, and understanding the challenges its introduction poses on relationships between healthcare providers and patients will require a regulatory and behavioral approach that can provide a guiding base for all users involved. In this paper, we present IAC (Informing, Assessment, and Consent), a framework for evaluating patient response to the introduction of AI-enabled digital technologies in healthcare settings. We justify the need for IAC with a general introduction of the challenges with and perceived relevance of AI in human-welfare-centered fields, with an emphasis on the provision of healthcare. The framework is composed of three core principles that guide how healthcare practitioners can inform patients about the use of AI in their healthcare, how practitioners can assess patients' acceptability and comfortability with the use of AI, and how patient consent can be gained after this process. We propose that the principles composing this framework can be translated into guidelines that improve practitioner-patient relationships and, concurrently, patient agency regarding the use of AI in healthcare while broadening the discourse on this topic.
Large Language Models (LLMs) have shown promise in the autonomous driving sector, particularly in generalization and interpretability. We introduce a unique object-level multimodal LLM architecture that merges vectorized numeric modalities with a pre-trained LLM to improve context understanding in driving situations. We also present a new dataset of 160k QA pairs derived from 10k driving scenarios, paired with high quality control commands collected with RL agent and question answer pairs generated by teacher LLM (GPT-3.5). A distinct pretraining strategy is devised to align numeric vector modalities with static LLM representations using vector captioning language data. We also introduce an evaluation metric for Driving QA and demonstrate our LLM-driver's proficiency in interpreting driving scenarios, answering questions, and decision-making. Our findings highlight the potential of LLM-based driving action generation in comparison to traditional behavioral cloning. We make our benchmark, datasets, and model available for further exploration.
Regarding the rising number of people suffering from mental health illnesses in today's society, the importance of mental health cannot be overstated. Wearable sensors, which are increasingly widely available, provide a potential way to track and comprehend mental health issues. These gadgets not only monitor everyday activities but also continuously record vital signs like heart rate, perhaps providing information on a person's mental state. Recent research has used these sensors in conjunction with machine learning methods to identify patterns relating to different mental health conditions, highlighting the immense potential of this data beyond simple activity monitoring. In this research, we present a novel algorithm called the Hybrid Random forest - Neural network that has been tailored to evaluate sensor data from depressed patients. Our method has a noteworthy accuracy of 80\% when evaluated on a special dataset that included both unipolar and bipolar depressive patients as well as healthy controls. The findings highlight the algorithm's potential for reliably determining a person's depression condition using sensor data, making a substantial contribution to the area of mental health diagnostics.
Achieving human-like dexterous manipulation remains a crucial area of research in robotics. Current research focuses on improving the success rate of pick-and-place tasks. Compared with pick-and-place, throw-catching behavior has the potential to increase picking speed without transporting objects to their destination. However, dynamic dexterous manipulation poses a major challenge for stable control due to a large number of dynamic contacts. In this paper, we propose a Stability-Constrained Reinforcement Learning (SCRL) algorithm to learn to catch diverse objects with dexterous hands. The SCRL algorithm outperforms baselines by a large margin, and the learned policies show strong zero-shot transfer performance on unseen objects. Remarkably, even though the object in a hand facing sideward is extremely unstable due to the lack of support from the palm, our method can still achieve a high level of success in the most challenging task. Video demonstrations of learned behaviors and the code can be found on the supplementary website.
In pace with developments in the research field of artificial intelligence, knowledge graphs (KGs) have attracted a surge of interest from both academia and industry. As a representation of semantic relations between entities, KGs have proven to be particularly relevant for natural language processing (NLP), experiencing a rapid spread and wide adoption within recent years. Given the increasing amount of research work in this area, several KG-related approaches have been surveyed in the NLP research community. However, a comprehensive study that categorizes established topics and reviews the maturity of individual research streams remains absent to this day. Contributing to closing this gap, we systematically analyzed 507 papers from the literature on KGs in NLP. Our survey encompasses a multifaceted review of tasks, research types, and contributions. As a result, we present a structured overview of the research landscape, provide a taxonomy of tasks, summarize our findings, and highlight directions for future work.
Designing and generating new data under targeted properties has been attracting various critical applications such as molecule design, image editing and speech synthesis. Traditional hand-crafted approaches heavily rely on expertise experience and intensive human efforts, yet still suffer from the insufficiency of scientific knowledge and low throughput to support effective and efficient data generation. Recently, the advancement of deep learning induces expressive methods that can learn the underlying representation and properties of data. Such capability provides new opportunities in figuring out the mutual relationship between the structural patterns and functional properties of the data and leveraging such relationship to generate structural data given the desired properties. This article provides a systematic review of this promising research area, commonly known as controllable deep data generation. Firstly, the potential challenges are raised and preliminaries are provided. Then the controllable deep data generation is formally defined, a taxonomy on various techniques is proposed and the evaluation metrics in this specific domain are summarized. After that, exciting applications of controllable deep data generation are introduced and existing works are experimentally analyzed and compared. Finally, the promising future directions of controllable deep data generation are highlighted and five potential challenges are identified.
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