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Statistical inferences for high-dimensional regression models have been extensively studied for their wide applications ranging from genomics, neuroscience, to economics. However, in practice, there are often potential unmeasured confounders associated with both the response and covariates, which can lead to invalidity of standard debiasing methods. This paper focuses on a generalized linear regression framework with hidden confounding and proposes a debiasing approach to address this high-dimensional problem, by adjusting for the effects induced by the unmeasured confounders. We establish consistency and asymptotic normality for the proposed debiased estimator. The finite sample performance of the proposed method is demonstrated through extensive numerical studies and an application to a genetic data set.

Distributed stochastic gradient descent (SGD) with gradient compression has become a popular communication-efficient solution for accelerating distributed learning. One commonly used method for gradient compression is Top-K sparsification, which sparsifies the gradients by a fixed degree during model training. However, there has been a lack of an adaptive approach to adjust the sparsification degree to maximize the potential of the model's performance or training speed. This paper proposes a novel adaptive Top-K in SGD framework that enables an adaptive degree of sparsification for each gradient descent step to optimize the convergence performance by balancing the trade-off between communication cost and convergence error. Firstly, an upper bound of convergence error is derived for the adaptive sparsification scheme and the loss function. Secondly, an algorithm is designed to minimize the convergence error under the communication cost constraints. Finally, numerical results on the MNIST and CIFAR-10 datasets demonstrate that the proposed adaptive Top-K algorithm in SGD achieves a significantly better convergence rate compared to state-of-the-art methods, even after considering error compensation.

Stable diffusion, a generative model used in text-to-image synthesis, frequently encounters resolution-induced composition problems when generating images of varying sizes. This issue primarily stems from the model being trained on pairs of single-scale images and their corresponding text descriptions. Moreover, direct training on images of unlimited sizes is unfeasible, as it would require an immense number of text-image pairs and entail substantial computational expenses. To overcome these challenges, we propose a two-stage pipeline named Any-Size-Diffusion (ASD), designed to efficiently generate well-composed images of any size, while minimizing the need for high-memory GPU resources. Specifically, the initial stage, dubbed Any Ratio Adaptability Diffusion (ARAD), leverages a selected set of images with a restricted range of ratios to optimize the text-conditional diffusion model, thereby improving its ability to adjust composition to accommodate diverse image sizes. To support the creation of images at any desired size, we further introduce a technique called Fast Seamless Tiled Diffusion (FSTD) at the subsequent stage. This method allows for the rapid enlargement of the ASD output to any high-resolution size, avoiding seaming artifacts or memory overloads. Experimental results on the LAION-COCO and MM-CelebA-HQ benchmarks demonstrate that ASD can produce well-structured images of arbitrary sizes, cutting down the inference time by 2x compared to the traditional tiled algorithm.

Physics-informed Neural Network (PINN) is one of the most preeminent solvers of Navier-Stokes equations, which are widely used as the governing equation of blood flow. However, current approaches, relying on full Navier-Stokes equations, are impractical for ultrafast Doppler ultrasound, the state-of-the-art technique for depiction of complex blood flow dynamics \emph{in vivo} through acquired thousands of frames (or, timestamps) per second. In this article, we first propose a novel training framework of PINN for solving Navier-Stokes equations by discretizing Navier-Stokes equations into steady state and sequentially solving steady-state Navier-Stokes equations with transfer learning. The novel training framework is coined as SeqPINN. Upon the success of SeqPINN, we adopt the idea of averaged constant stochastic gradient descent (SGD) as initialization and propose a parallel training scheme for all timestamps. To ensure an initialization that generalizes well, we borrow the concept of Stochastic Weight Averaging Gaussian to perform uncertainty estimation as an indicator of generalizability of the initialization. This algorithm, named SP-PINN, further expedites training of PINN while achieving comparable accuracy with SeqPINN. Finite-element simulations and \emph{in vitro} phantoms of single-branch and trifurcate blood vessels are used to evaluate the performance of SeqPINN and SP-PINN. Results show that both SeqPINN and SP-PINN are manyfold faster than the original design of PINN, while respectively achieving Root Mean Square Errors (RMSEs) of 1.01 cm/s and 1.26 cm/s on the straight vessel and 1.91 cm/s and 2.56 cm/s on the trifurcate blood vessel when recovering blood flow velocities.

The Function-as-a-service (FaaS) computing model has recently seen significant growth especially for highly scalable, event-driven applications. The easy-to-deploy and cost-efficient fine-grained billing of FaaS is highly attractive to big data applications. However, the stateless nature of serverless platforms poses major challenges when supporting stateful I/O intensive workloads such as a lack of native support for stateful execution, state sharing, and inter-function communication. In this paper, we explore the feasibility of performing stateful big data analytics on serverless platforms and improving I/O throughput of functions by using modern storage technologies such as Intel Optane DC Persistent Memory (PMEM). To this end, we propose Marvel, an end-to-end architecture built on top of the popular serverless platform, Apache OpenWhisk and Apache Hadoop. Marvel makes two main contributions: (1) enable stateful function execution on OpenWhisk by maintaining state information in an in-memory caching layer; and (2) provide access to PMEM backed HDFS storage for faster I/O performance. Our evaluation shows that Marvel reduces the overall execution time of big data applications by up to 86.6% compared to current MapReduce implementations on AWS Lambda.

2D-based Industrial Anomaly Detection has been widely discussed, however, multimodal industrial anomaly detection based on 3D point clouds and RGB images still has many untouched fields. Existing multimodal industrial anomaly detection methods directly concatenate the multimodal features, which leads to a strong disturbance between features and harms the detection performance. In this paper, we propose Multi-3D-Memory (M3DM), a novel multimodal anomaly detection method with hybrid fusion scheme: firstly, we design an unsupervised feature fusion with patch-wise contrastive learning to encourage the interaction of different modal features; secondly, we use a decision layer fusion with multiple memory banks to avoid loss of information and additional novelty classifiers to make the final decision. We further propose a point feature alignment operation to better align the point cloud and RGB features. Extensive experiments show that our multimodal industrial anomaly detection model outperforms the state-of-the-art (SOTA) methods on both detection and segmentation precision on MVTec-3D AD dataset. Code is available at //github.com/nomewang/M3DM.

With the urgent demand for generalized deep models, many pre-trained big models are proposed, such as BERT, ViT, GPT, etc. Inspired by the success of these models in single domains (like computer vision and natural language processing), the multi-modal pre-trained big models have also drawn more and more attention in recent years. In this work, we give a comprehensive survey of these models and hope this paper could provide new insights and helps fresh researchers to track the most cutting-edge works. Specifically, we firstly introduce the background of multi-modal pre-training by reviewing the conventional deep learning, pre-training works in natural language process, computer vision, and speech. Then, we introduce the task definition, key challenges, and advantages of multi-modal pre-training models (MM-PTMs), and discuss the MM-PTMs with a focus on data, objectives, network architectures, and knowledge enhanced pre-training. After that, we introduce the downstream tasks used for the validation of large-scale MM-PTMs, including generative, classification, and regression tasks. We also give visualization and analysis of the model parameters and results on representative downstream tasks. Finally, we point out possible research directions for this topic that may benefit future works. In addition, we maintain a continuously updated paper list for large-scale pre-trained multi-modal big models: //github.com/wangxiao5791509/MultiModal_BigModels_Survey

Pre-trained Language Models (PLMs) which are trained on large text corpus via self-supervised learning method, have yielded promising performance on various tasks in Natural Language Processing (NLP). However, though PLMs with huge parameters can effectively possess rich knowledge learned from massive training text and benefit downstream tasks at the fine-tuning stage, they still have some limitations such as poor reasoning ability due to the lack of external knowledge. Research has been dedicated to incorporating knowledge into PLMs to tackle these issues. In this paper, we present a comprehensive review of Knowledge-Enhanced Pre-trained Language Models (KE-PLMs) to provide a clear insight into this thriving field. We introduce appropriate taxonomies respectively for Natural Language Understanding (NLU) and Natural Language Generation (NLG) to highlight these two main tasks of NLP. For NLU, we divide the types of knowledge into four categories: linguistic knowledge, text knowledge, knowledge graph (KG), and rule knowledge. The KE-PLMs for NLG are categorized into KG-based and retrieval-based methods. Finally, we point out some promising future directions of KE-PLMs.

Conventional entity typing approaches are based on independent classification paradigms, which make them difficult to recognize inter-dependent, long-tailed and fine-grained entity types. In this paper, we argue that the implicitly entailed extrinsic and intrinsic dependencies between labels can provide critical knowledge to tackle the above challenges. To this end, we propose \emph{Label Reasoning Network(LRN)}, which sequentially reasons fine-grained entity labels by discovering and exploiting label dependencies knowledge entailed in the data. Specifically, LRN utilizes an auto-regressive network to conduct deductive reasoning and a bipartite attribute graph to conduct inductive reasoning between labels, which can effectively model, learn and reason complex label dependencies in a sequence-to-set, end-to-end manner. Experiments show that LRN achieves the state-of-the-art performance on standard ultra fine-grained entity typing benchmarks, and can also resolve the long tail label problem effectively.