Physiological responses to pain have received increasing attention among researchers for developing an automated pain recognition sensing system. Though less explored, Blood Volume Pulse (BVP) is one of the candidate physiological measures that could help objective pain assessment. In this study, we applied machine learning techniques on BVP signals to device a non-invasive modality for pain sensing. Thirty-two healthy subjects participated in this study. First, we investigated a novel set of time-domain, frequency-domain and nonlinear dynamics features that could potentially be sensitive to pain. These include 24 features from BVP signals and 20 additional features from Inter-beat Intervals (IBIs) derived from the same BVP signals. Utilizing these features, we built machine learning models for detecting the presence of pain and its intensity. We explored different machine learning models, including Logistic Regression, Random Forest, Support Vector Machines, Adaptive Boosting (AdaBoost) and Extreme Gradient Boosting (XGBoost). Among them, we found that the XGBoost offered the best model performance for both pain classification and pain intensity estimation tasks. The ROC-AUC of the XGBoost model to detect low pain, medium pain and high pain with no pain as the baseline were 80.06 %, 85.81 %, and 90.05 % respectively. Moreover, the XGboost classifier distinguished medium pain from high pain with ROC-AUC of 91%. For the multi-class classification among three pain levels, the XGBoost offered the best performance with an average F1-score of 80.03%. Our results suggest that BVP signal together with machine learning algorithms is a promising physiological measurement for automated pain assessment. This work will have a national impact on accurate pain assessment, effective pain management, reducing drug-seeking behavior among patients, and addressing national opioid crisis.
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Cardiovascular diseases (CVDs) are responsible for a large proportion of premature deaths in low- and middle-income countries. Early CVD detection and intervention is critical in these populations, yet many existing CVD risk scores require a physical examination or lab measurements, which can be challenging in such health systems due to limited accessibility. Here we investigated the potential to use photoplethysmography (PPG), a sensing technology available on most smartphones that can potentially enable large-scale screening at low cost, for CVD risk prediction. We developed a deep learning PPG-based CVD risk score (DLS) to predict the probability of having major adverse cardiovascular events (MACE: non-fatal myocardial infarction, stroke, and cardiovascular death) within ten years, given only age, sex, smoking status and PPG as predictors. We compared the DLS with the office-based refit-WHO score, which adopts the shared predictors from WHO and Globorisk scores (age, sex, smoking status, height, weight and systolic blood pressure) but refitted on the UK Biobank (UKB) cohort. In UKB cohort, DLS's C-statistic (71.1%, 95% CI 69.9-72.4) was non-inferior to office-based refit-WHO score (70.9%, 95% CI 69.7-72.2; non-inferiority margin of 2.5%, p<0.01). The calibration of the DLS was satisfactory, with a 1.8% mean absolute calibration error. Adding DLS features to the office-based score increased the C-statistic by 1.0% (95% CI 0.6-1.4). DLS predicts ten-year MACE risk comparable with the office-based refit-WHO score. It provides a proof-of-concept and suggests the potential of a PPG-based approach strategies for community-based primary prevention in resource-limited regions.
This paper presents a method for real-time estimation of 2-dimensional direction of arrival (2D-DOA) of one or more sound sources using a nonlinear array of three microphones. 2D-DOA is estimated employing frame-level time difference of arrival (TDOA) measurements. Unlike conventional methods, which infer location parameters from TDOAs using a theoretical model, we propose a more practical approach based on supervised learning. The proposed model employs nearest neighbor search (NNS) applied to a spherical Fibonacci lattice consisting of TDOA to 2D-DOA mappings learned directly in the field. Filtering and clustering post-processors are also introduced for improved source detection and localization robustness.
Data transfers are essential in today's computing systems as latency and complex memory access patterns are increasingly challenging to manage. Direct memory access engines (DMAEs) are critically needed to transfer data independently of the processing elements, hiding latency and achieving high throughput even for complex access patterns to high-latency memory. With the prevalence of heterogeneous systems, DMAEs must operate efficiently in increasingly diverse environments. This work proposes a modular and highly configurable open-source DMAE architecture called intelligent DMA (iDMA), split into three parts that can be composed and customized independently. The front-end implements the control plane binding to the surrounding system. The mid-end accelerates complex data transfer patterns such as multi-dimensional transfers, scattering, or gathering. The back-end interfaces with the on-chip communication fabric (data plane). We assess the efficiency of iDMA in various instantiations: In high-performance systems, we achieve speedups of up to 15.8x with only 1 % additional area compared to a base system without a DMAE. We achieve an area reduction of 10 % while improving ML inference performance by 23 % in ultra-low-energy edge AI systems over an existing DMAE solution. We provide area, timing, latency, and performance characterization to guide its instantiation in various systems.
The first ACM/IEEE TinyML Design Contest (TDC) held at the 41st International Conference on Computer-Aided Design (ICCAD) in 2022 is a challenging, multi-month, research and development competition. TDC'22 focuses on real-world medical problems that require the innovation and implementation of artificial intelligence/machine learning (AI/ML) algorithms on implantable devices. The challenge problem of TDC'22 is to develop a novel AI/ML-based real-time detection algorithm for life-threatening ventricular arrhythmia over low-power microcontrollers utilized in Implantable Cardioverter-Defibrillators (ICDs). The dataset contains more than 38,000 5-second intracardiac electrograms (IEGMs) segments over 8 different types of rhythm from 90 subjects. The dedicated hardware platform is NUCLEO-L432KC manufactured by STMicroelectronics. TDC'22, which is open to multi-person teams world-wide, attracted more than 150 teams from over 50 organizations. This paper first presents the medical problem, dataset, and evaluation procedure in detail. It further demonstrates and discusses the designs developed by the leading teams as well as representative results. This paper concludes with the direction of improvement for the future TinyML design for health monitoring applications.
This paper presents an efficient Multi-scale Transformer-based approach for the task of Emotion recognition from Physiological data, which has gained widespread attention in the research community due to the vast amount of information that can be extracted from these signals using modern sensors and machine learning techniques. Our approach involves applying a Multi-modal technique combined with scaling data to establish the relationship between internal body signals and human emotions. Additionally, we utilize Transformer and Gaussian Transformation techniques to improve signal encoding effectiveness and overall performance. Our model achieves decent results on the CASE dataset of the EPiC competition, with an RMSE score of 1.45.
Photoplethysmography (PPG) signals have become a key technology in many fields, such as medicine, well-being, or sports. Our work proposes a set of pipelines to extract remote PPG signals (rPPG) from the face robustly, reliably, and configurable. We identify and evaluate the possible choices in the critical steps of unsupervised rPPG methodologies. We assess a state-of-the-art processing pipeline in six different datasets, incorporating important corrections in the methodology that ensure reproducible and fair comparisons. In addition, we extend the pipeline by proposing three novel ideas; 1) a new method to stabilize the detected face based on a rigid mesh normalization; 2) a new method to dynamically select the different regions in the face that provide the best raw signals, and 3) a new RGB to rPPG transformation method, called Orthogonal Matrix Image Transformation (OMIT) based on QR decomposition, that increases robustness against compression artifacts. We show that all three changes introduce noticeable improvements in retrieving rPPG signals from faces, obtaining state-of-the-art results compared with unsupervised, non-learning-based methodologies and, in some databases, very close to supervised, learning-based methods. We perform a comparative study to quantify the contribution of each proposed idea. In addition, we depict a series of observations that could help in future implementations.
Over the past few years, the rapid development of deep learning technologies for computer vision has greatly promoted the performance of medical image segmentation (MedISeg). However, the recent MedISeg publications usually focus on presentations of the major contributions (e.g., network architectures, training strategies, and loss functions) while unwittingly ignoring some marginal implementation details (also known as "tricks"), leading to a potential problem of the unfair experimental result comparisons. In this paper, we collect a series of MedISeg tricks for different model implementation phases (i.e., pre-training model, data pre-processing, data augmentation, model implementation, model inference, and result post-processing), and experimentally explore the effectiveness of these tricks on the consistent baseline models. Compared to paper-driven surveys that only blandly focus on the advantages and limitation analyses of segmentation models, our work provides a large number of solid experiments and is more technically operable. With the extensive experimental results on both the representative 2D and 3D medical image datasets, we explicitly clarify the effect of these tricks. Moreover, based on the surveyed tricks, we also open-sourced a strong MedISeg repository, where each of its components has the advantage of plug-and-play. We believe that this milestone work not only completes a comprehensive and complementary survey of the state-of-the-art MedISeg approaches, but also offers a practical guide for addressing the future medical image processing challenges including but not limited to small dataset learning, class imbalance learning, multi-modality learning, and domain adaptation. The code has been released at: //github.com/hust-linyi/MedISeg
This survey paper specially analyzed computer vision-based object detection challenges and solutions by different techniques. We mainly highlighted object detection by three different trending strategies, i.e., 1) domain adaptive deep learning-based approaches (discrepancy-based, Adversarial-based, Reconstruction-based, Hybrid). We examined general as well as tiny object detection-related challenges and offered solutions by historical and comparative analysis. In part 2) we mainly focused on tiny object detection techniques (multi-scale feature learning, Data augmentation, Training strategy (TS), Context-based detection, GAN-based detection). In part 3), To obtain knowledge-able findings, we discussed different object detection methods, i.e., convolutions and convolutional neural networks (CNN), pooling operations with trending types. Furthermore, we explained results with the help of some object detection algorithms, i.e., R-CNN, Fast R-CNN, Faster R-CNN, YOLO, and SSD, which are generally considered the base bone of CV, CNN, and OD. We performed comparative analysis on different datasets such as MS-COCO, PASCAL VOC07,12, and ImageNet to analyze results and present findings. At the end, we showed future directions with existing challenges of the field. In the future, OD methods and models can be analyzed for real-time object detection, tracking strategies.
Deep Learning has implemented a wide range of applications and has become increasingly popular in recent years. The goal of multimodal deep learning is to create models that can process and link information using various modalities. Despite the extensive development made for unimodal learning, it still cannot cover all the aspects of human learning. Multimodal learning helps to understand and analyze better when various senses are engaged in the processing of information. This paper focuses on multiple types of modalities, i.e., image, video, text, audio, body gestures, facial expressions, and physiological signals. Detailed analysis of past and current baseline approaches and an in-depth study of recent advancements in multimodal deep learning applications has been provided. A fine-grained taxonomy of various multimodal deep learning applications is proposed, elaborating on different applications in more depth. Architectures and datasets used in these applications are also discussed, along with their evaluation metrics. Last, main issues are highlighted separately for each domain along with their possible future research directions.
Sentiment analysis is a widely studied NLP task where the goal is to determine opinions, emotions, and evaluations of users towards a product, an entity or a service that they are reviewing. One of the biggest challenges for sentiment analysis is that it is highly language dependent. Word embeddings, sentiment lexicons, and even annotated data are language specific. Further, optimizing models for each language is very time consuming and labor intensive especially for recurrent neural network models. From a resource perspective, it is very challenging to collect data for different languages. In this paper, we look for an answer to the following research question: can a sentiment analysis model trained on a language be reused for sentiment analysis in other languages, Russian, Spanish, Turkish, and Dutch, where the data is more limited? Our goal is to build a single model in the language with the largest dataset available for the task, and reuse it for languages that have limited resources. For this purpose, we train a sentiment analysis model using recurrent neural networks with reviews in English. We then translate reviews in other languages and reuse this model to evaluate the sentiments. Experimental results show that our robust approach of single model trained on English reviews statistically significantly outperforms the baselines in several different languages.
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