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Background: The semantics of entities extracted from a clinical text can be dramatically altered by modifiers, including entity negation, uncertainty, conditionality, severity, and subject. Existing models for determining modifiers of clinical entities involve regular expression or features weights that are trained independently for each modifier. Methods: We develop and evaluate a multi-task transformer architecture design where modifiers are learned and predicted jointly using the publicly available SemEval 2015 Task 14 corpus and a new Opioid Use Disorder (OUD) data set that contains modifiers shared with SemEval as well as novel modifiers specific for OUD. We evaluate the effectiveness of our multi-task learning approach versus previously published systems and assess the feasibility of transfer learning for clinical entity modifiers when only a portion of clinical modifiers are shared. Results: Our approach achieved state-of-the-art results on the ShARe corpus from SemEval 2015 Task 14, showing an increase of 1.1% on weighted accuracy, 1.7% on unweighted accuracy, and 10% on micro F1 scores. Conclusions: We show that learned weights from our shared model can be effectively transferred to a new partially matched data set, validating the use of transfer learning for clinical text modifiers

Closely related languages show linguistic similarities that allow speakers of one language to understand speakers of another language without having actively learned it. Mutual intelligibility varies in degree and is typically tested in psycholinguistic experiments. To study mutual intelligibility computationally, we propose a computer-assisted method using the Linear Discriminative Learner, a computational model developed to approximate the cognitive processes by which humans learn languages, which we expand with multilingual semantic vectors and multilingual sound classes. We test the model on cognate data from German, Dutch, and English, three closely related Germanic languages. We find that our model's comprehension accuracy depends on 1) the automatic trimming of inflections and 2) the language pair for which comprehension is tested. Our multilingual modelling approach does not only offer new methodological findings for automatic testing of mutual intelligibility across languages but also extends the use of Linear Discriminative Learning to multilingual settings.

The remarkable capability of large language models (LLMs) in generating high-quality code has drawn increasing attention in the software testing community. However, existing code LLMs often demonstrate unsatisfactory capabilities in generating accurate and complete tests since they were trained on code snippets collected without differentiating between code for testing purposes and other code. In this paper, we present a large-scale dataset UniTSyn, which is capable of enhancing the prowess of LLMs for Unit Test Synthesis. Associating tests with the tested functions is crucial for LLMs to infer the expected behavior and the logic paths to be verified. By leveraging Language Server Protocol, UniTSyn achieves the challenging goal of collecting focal-test pairs without per-project execution setups or per-language heuristics that tend to be fragile and difficult to scale. It contains 2.7 million focal-test pairs across five mainstream programming languages, making it possible to be utilized for enhancing the test generation ability of LLMs. The details of UniTSyn can be found in Table 1. Our experiments demonstrate that, by building an autoregressive model based on UniTSyn, we can achieve significant benefits in learning and understanding unit test representations, resulting in improved generation accuracy and code coverage across all evaluated programming languages. Code and data will be publicly available.

The success of retrieval-augmented language models in various natural language processing (NLP) tasks has been constrained in automatic speech recognition (ASR) applications due to challenges in constructing fine-grained audio-text datastores. This paper presents kNN-CTC, a novel approach that overcomes these challenges by leveraging Connectionist Temporal Classification (CTC) pseudo labels to establish frame-level audio-text key-value pairs, circumventing the need for precise ground truth alignments. We further introduce a skip-blank strategy, which strategically ignores CTC blank frames, to reduce datastore size. kNN-CTC incorporates a k-nearest neighbors retrieval mechanism into pre-trained CTC ASR systems, achieving significant improvements in performance. By incorporating a k-nearest neighbors retrieval mechanism into pre-trained CTC ASR systems and leveraging a fine-grained, pruned datastore, kNN-CTC consistently achieves substantial improvements in performance under various experimental settings. Our code is available at //github.com/NKU-HLT/KNN-CTC.

Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. LLMs in medicine to assist physicians for patient care are emerging as a promising research direction in both artificial intelligence and clinical medicine. This review provides a comprehensive overview of the principles, applications, and challenges faced by LLMs in medicine. We address the following specific questions: 1) How should medical LLMs be built? 2) What are the measures for the downstream performance of medical LLMs? 3) How should medical LLMs be utilized in real-world clinical practice? 4) What challenges arise from the use of medical LLMs? and 5) How should we better construct and utilize medical LLMs? This review aims to provide insights into the opportunities and challenges of LLMs in medicine, and serve as a practical resource for constructing effective medical LLMs. We also maintain and regularly updated list of practical guides on medical LLMs at //github.com/AI-in-Health/MedLLMsPracticalGuide.

Large language models (LLMs) exhibit superior performance on various natural language tasks, but they are susceptible to issues stemming from outdated data and domain-specific limitations. In order to address these challenges, researchers have pursued two primary strategies, knowledge editing and retrieval augmentation, to enhance LLMs by incorporating external information from different aspects. Nevertheless, there is still a notable absence of a comprehensive survey. In this paper, we propose a review to discuss the trends in integration of knowledge and large language models, including taxonomy of methods, benchmarks, and applications. In addition, we conduct an in-depth analysis of different methods and point out potential research directions in the future. We hope this survey offers the community quick access and a comprehensive overview of this research area, with the intention of inspiring future research endeavors.

While large language models (LLMs) have demonstrated remarkable capabilities across a range of downstream tasks, a significant concern revolves around their propensity to exhibit hallucinations: LLMs occasionally generate content that diverges from the user input, contradicts previously generated context, or misaligns with established world knowledge. This phenomenon poses a substantial challenge to the reliability of LLMs in real-world scenarios. In this paper, we survey recent efforts on the detection, explanation, and mitigation of hallucination, with an emphasis on the unique challenges posed by LLMs. We present taxonomies of the LLM hallucination phenomena and evaluation benchmarks, analyze existing approaches aiming at mitigating LLM hallucination, and discuss potential directions for future research.

The advent of large language models marks a revolutionary breakthrough in artificial intelligence. With the unprecedented scale of training and model parameters, the capability of large language models has been dramatically improved, leading to human-like performances in understanding, language synthesizing, and common-sense reasoning, etc. Such a major leap-forward in general AI capacity will change the pattern of how personalization is conducted. For one thing, it will reform the way of interaction between humans and personalization systems. Instead of being a passive medium of information filtering, large language models present the foundation for active user engagement. On top of such a new foundation, user requests can be proactively explored, and user's required information can be delivered in a natural and explainable way. For another thing, it will also considerably expand the scope of personalization, making it grow from the sole function of collecting personalized information to the compound function of providing personalized services. By leveraging large language models as general-purpose interface, the personalization systems may compile user requests into plans, calls the functions of external tools to execute the plans, and integrate the tools' outputs to complete the end-to-end personalization tasks. Today, large language models are still being developed, whereas the application in personalization is largely unexplored. Therefore, we consider it to be the right time to review the challenges in personalization and the opportunities to address them with LLMs. In particular, we dedicate this perspective paper to the discussion of the following aspects: the development and challenges for the existing personalization system, the newly emerged capabilities of large language models, and the potential ways of making use of large language models for personalization.

Large language models (LLMs) have significantly advanced the field of natural language processing (NLP), providing a highly useful, task-agnostic foundation for a wide range of applications. The great promise of LLMs as general task solvers motivated people to extend their functionality largely beyond just a ``chatbot'', and use it as an assistant or even replacement for domain experts and tools in specific domains such as healthcare, finance, and education. However, directly applying LLMs to solve sophisticated problems in specific domains meets many hurdles, caused by the heterogeneity of domain data, the sophistication of domain knowledge, the uniqueness of domain objectives, and the diversity of the constraints (e.g., various social norms, cultural conformity, religious beliefs, and ethical standards in the domain applications). To fill such a gap, explosively-increase research, and practices have been conducted in very recent years on the domain specialization of LLMs, which, however, calls for a comprehensive and systematic review to better summarizes and guide this promising domain. In this survey paper, first, we propose a systematic taxonomy that categorizes the LLM domain-specialization techniques based on the accessibility to LLMs and summarizes the framework for all the subcategories as well as their relations and differences to each other. We also present a comprehensive taxonomy of critical application domains that can benefit from specialized LLMs, discussing their practical significance and open challenges. Furthermore, we offer insights into the current research status and future trends in this area.