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There is an increasing interest in developing LLMs for medical diagnosis to improve diagnosis efficiency. Despite their alluring technological potential, there is no unified and comprehensive evaluation criterion, leading to the inability to evaluate the quality and potential risks of medical LLMs, further hindering the application of LLMs in medical treatment scenarios. Besides, current evaluations heavily rely on labor-intensive interactions with LLMs to obtain diagnostic dialogues and human evaluation on the quality of diagnosis dialogue. To tackle the lack of unified and comprehensive evaluation criterion, we first initially establish an evaluation criterion, termed LLM-specific Mini-CEX to assess the diagnostic capabilities of LLMs effectively, based on original Mini-CEX. To address the labor-intensive interaction problem, we develop a patient simulator to engage in automatic conversations with LLMs, and utilize ChatGPT for evaluating diagnosis dialogues automatically. Experimental results show that the LLM-specific Mini-CEX is adequate and necessary to evaluate medical diagnosis dialogue. Besides, ChatGPT can replace manual evaluation on the metrics of humanistic qualities and provides reproducible and automated comparisons between different LLMs.

The Segment Anything Model (SAM) serves as a fundamental model for semantic segmentation and demonstrates remarkable generalization capabilities across a wide range of downstream scenarios. In this empirical study, we examine SAM's robustness and zero-shot generalizability in the field of robotic surgery. We comprehensively explore different scenarios, including prompted and unprompted situations, bounding box and points-based prompt approaches, as well as the ability to generalize under corruptions and perturbations at five severity levels. Additionally, we compare the performance of SAM with state-of-the-art supervised models. We conduct all the experiments with two well-known robotic instrument segmentation datasets from MICCAI EndoVis 2017 and 2018 challenges. Our extensive evaluation results reveal that although SAM shows remarkable zero-shot generalization ability with bounding box prompts, it struggles to segment the whole instrument with point-based prompts and unprompted settings. Furthermore, our qualitative figures demonstrate that the model either failed to predict certain parts of the instrument mask (e.g., jaws, wrist) or predicted parts of the instrument as wrong classes in the scenario of overlapping instruments within the same bounding box or with the point-based prompt. In fact, SAM struggles to identify instruments in complex surgical scenarios characterized by the presence of blood, reflection, blur, and shade. Additionally, SAM is insufficiently robust to maintain high performance when subjected to various forms of data corruption. We also attempt to fine-tune SAM using Low-rank Adaptation (LoRA) and propose SurgicalSAM, which shows the capability in class-wise mask prediction without prompt. Therefore, we can argue that, without further domain-specific fine-tuning, SAM is not ready for downstream surgical tasks.

Understanding human interaction with objects is an important research topic for embodied Artificial Intelligence and identifying the objects that humans are interacting with is a primary problem for interaction understanding. Existing methods rely on frame-based detectors to locate interacting objects. However, this approach is subjected to heavy occlusions, background clutter, and distracting objects. To address the limitations, in this paper, we propose to leverage spatio-temporal information of hand-object interaction to track interactive objects under these challenging cases. Without prior knowledge of the general objects to be tracked like object tracking problems, we first utilize the spatial relation between hands and objects to adaptively discover the interacting objects from the scene. Second, the consistency and continuity of the appearance of objects between successive frames are exploited to track the objects. With this tracking formulation, our method also benefits from training on large-scale general object-tracking datasets. We further curate a video-level hand-object interaction dataset for testing and evaluation from 100DOH. The quantitative results demonstrate that our proposed method outperforms the state-of-the-art methods. Specifically, in scenes with continuous interaction with different objects, we achieve an impressive improvement of about 10% as evaluated using the Average Precision (AP) metric. Our qualitative findings also illustrate that our method can produce more continuous trajectories for interacting objects.

The morbidity of scalp diseases is minuscule compared to other diseases, but the impact on the patient's life is enormous. It is common for people to experience scalp problems that include Dandruff, Psoriasis, Tinea-Capitis, Alopecia and Atopic-Dermatitis. In accordance with WHO research, approximately 70% of adults have problems with their scalp. It has been demonstrated in descriptive research that hair quality is impaired by impaired scalp, but these impacts are reversible with early diagnosis and treatment. Deep Learning advances have demonstrated the effectiveness of CNN paired with FCN in diagnosing scalp and skin disorders. In one proposed Deep-Learning-based scalp inspection and diagnosis system, an imaging microscope and a trained model are combined with an app that classifies scalp disorders accurately with an average precision of 97.41%- 99.09%. Another research dealt with classifying the Psoriasis using the CNN with an accuracy of 82.9%. As part of another study, an ML based algorithm was also employed. It accurately classified the healthy scalp and alopecia areata with 91.4% and 88.9% accuracy with SVM and KNN algorithms. Using deep learning models to diagnose scalp related diseases has improved due to advancements i computation capabilities and computer vision, but there remains a wide horizon for further improvements.

Automated segmentation of ultrasound images can assist medical experts with diagnostic and therapeutic procedures. Although using the common modality of ultrasound, one typically needs separate datasets in order to segment, for example, different anatomical structures or lesions with different levels of malignancy. In this paper, we consider the problem of jointly learning from heterogeneous datasets so that the model can improve generalization abilities by leveraging the inherent variability among datasets. We merge the heterogeneous datasets into one dataset and refer to each component dataset as a subgroup. We propose to train a single segmentation model so that the model can adapt to each sub-group. For robust segmentation, we leverage recently proposed Segment Anything model (SAM) in order to incorporate sub-group information into the model. We propose SAM with Condition Embedding block (CEmb-SAM) which encodes sub-group conditions and combines them with image embeddings from SAM. The conditional embedding block effectively adapts SAM to each image sub-group by incorporating dataset properties through learnable parameters for normalization. Experiments show that CEmb-SAM outperforms the baseline methods on ultrasound image segmentation for peripheral nerves and breast cancer. The experiments highlight the effectiveness of Cemb-SAM in learning from heterogeneous datasets in medical image segmentation tasks.

Causal inference is a crucial goal of science, enabling researchers to arrive at meaningful conclusions regarding the predictions of hypothetical interventions using observational data. Path models, Structural Equation Models (SEMs), and, more generally, Directed Acyclic Graphs (DAGs), provide a means to unambiguously specify assumptions regarding the causal structure underlying a phenomenon. Unlike DAGs, which make very few assumptions about the functional and parametric form, SEM assumes linearity. This can result in functional misspecification which prevents researchers from undertaking reliable effect size estimation. In contrast, we propose Super Learner Equation Modeling, a path modeling technique integrating machine learning Super Learner ensembles. We empirically demonstrate its ability to provide consistent and unbiased estimates of causal effects, its competitive performance for linear models when compared with SEM, and highlight its superiority over SEM when dealing with non-linear relationships. We provide open-source code, and a tutorial notebook with example usage, accentuating the easy-to-use nature of the method.

Mentions of new concepts appear regularly in texts and require automated approaches to harvest and place them into Knowledge Bases (KB), e.g., ontologies and taxonomies. Existing datasets suffer from three issues, (i) mostly assuming that a new concept is pre-discovered and cannot support out-of-KB mention discovery; (ii) only using the concept label as the input along with the KB and thus lacking the contexts of a concept label; and (iii) mostly focusing on concept placement w.r.t a taxonomy of atomic concepts, instead of complex concepts, i.e., with logical operators. To address these issues, we propose a new benchmark, adapting MedMentions dataset (PubMed abstracts) with SNOMED CT versions in 2014 and 2017 under the Diseases sub-category and the broader categories of Clinical finding, Procedure, and Pharmaceutical / biologic product. We provide usage on the evaluation with the dataset for out-of-KB mention discovery and concept placement, adapting recent Large Language Model based methods.

Graph Neural Networks (GNNs) have been studied from the lens of expressive power and generalization. However, their optimization properties are less well understood. We take the first step towards analyzing GNN training by studying the gradient dynamics of GNNs. First, we analyze linearized GNNs and prove that despite the non-convexity of training, convergence to a global minimum at a linear rate is guaranteed under mild assumptions that we validate on real-world graphs. Second, we study what may affect the GNNs' training speed. Our results show that the training of GNNs is implicitly accelerated by skip connections, more depth, and/or a good label distribution. Empirical results confirm that our theoretical results for linearized GNNs align with the training behavior of nonlinear GNNs. Our results provide the first theoretical support for the success of GNNs with skip connections in terms of optimization, and suggest that deep GNNs with skip connections would be promising in practice.

Defensive deception is a promising approach for cyberdefense. Although defensive deception is increasingly popular in the research community, there has not been a systematic investigation of its key components, the underlying principles, and its tradeoffs in various problem settings. This survey paper focuses on defensive deception research centered on game theory and machine learning, since these are prominent families of artificial intelligence approaches that are widely employed in defensive deception. This paper brings forth insights, lessons, and limitations from prior work. It closes with an outline of some research directions to tackle major gaps in current defensive deception research.

Many natural language processing tasks solely rely on sparse dependencies between a few tokens in a sentence. Soft attention mechanisms show promising performance in modeling local/global dependencies by soft probabilities between every two tokens, but they are not effective and efficient when applied to long sentences. By contrast, hard attention mechanisms directly select a subset of tokens but are difficult and inefficient to train due to their combinatorial nature. In this paper, we integrate both soft and hard attention into one context fusion model, "reinforced self-attention (ReSA)", for the mutual benefit of each other. In ReSA, a hard attention trims a sequence for a soft self-attention to process, while the soft attention feeds reward signals back to facilitate the training of the hard one. For this purpose, we develop a novel hard attention called "reinforced sequence sampling (RSS)", selecting tokens in parallel and trained via policy gradient. Using two RSS modules, ReSA efficiently extracts the sparse dependencies between each pair of selected tokens. We finally propose an RNN/CNN-free sentence-encoding model, "reinforced self-attention network (ReSAN)", solely based on ReSA. It achieves state-of-the-art performance on both Stanford Natural Language Inference (SNLI) and Sentences Involving Compositional Knowledge (SICK) datasets.