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In the modeling of parasite transmission dynamics, understanding the reproductive characteristics of these parasites is crucial. This paper presents a mathematical model that explores the reproductive behavior of dioecious parasites and its impact on transmission dynamics. Specifically, the study focuses on the investigation of various reproductive variables such as the mating probability and the fertilized egg production in the case of helminth parasites. While previous studies have commonly assumed Poisson and negative binomial distributions to describe the distribution of parasites among hosts, this study adopts an arbitrary distribution model and examines its consequences on some reproductive variables. These variables include mean number of fertile females, mean egg production, mating probability and mean fertilized egg production. In addition, the study of these variables takes into account the sex distribution of the parasites and whether male and female parasites are considered to be distributed together or separately. We show that the models obtained for the case of male and female parasites distributed separately in the hosts are ecologically unrealistic. We present the results obtained for some specific models and we tested the models obtained in this work using Monte Carlo simulations.

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ACM/IEEE第23屆模型驅動工程語言和系統國際會議,是模型驅動軟件和系統工程的首要會議系列,由ACM-SIGSOFT和IEEE-TCSE支持組織。自1998年以來,模型涵蓋了建模的各個方面,從語言和方法到工具和應用程序。模特的參加者來自不同的背景,包括研究人員、學者、工程師和工業專業人士。MODELS 2019是一個論壇,參與者可以圍繞建模和模型驅動的軟件和系統交流前沿研究成果和創新實踐經驗。今年的版本將為建模社區提供進一步推進建模基礎的機會,并在網絡物理系統、嵌入式系統、社會技術系統、云計算、大數據、機器學習、安全、開源等新興領域提出建模的創新應用以及可持續性。 官網鏈接: · 情景 · JACM · 相互獨立的 · 泛化理論 ·
2023 年 7 月 17 日

We study the complexity of evaluating queries on probabilistic databases under bag semantics. We focus on self-join free conjunctive queries, and probabilistic databases where occurrences of different facts are independent, which is the natural generalization of tuple-independent probabilistic databases to the bag semantics setting. For set semantics, the data complexity of this problem is well understood, even for the more general class of unions of conjunctive queries: it is either in polynomial time, or #P-hard, depending on the query (Dalvi & Suciu, JACM 2012). A reasonably general model of bag probabilistic databases may have unbounded multiplicities. In this case, the probabilistic database is no longer finite, and a careful treatment of representation mechanisms is required. Moreover, the answer to a Boolean query is a probability distribution over (possibly all) non-negative integers, rather than a probability distribution over { true, false }. Therefore, we discuss two flavors of probabilistic query evaluation: computing expectations of answer tuple multiplicities, and computing the probability that a tuple is contained in the answer at most k times for some parameter k. Subject to mild technical assumptions on the representation systems, it turns out that expectations are easy to compute, even for unions of conjunctive queries. For query answer probabilities, we obtain a dichotomy between solvability in polynomial time and #P-hardness for self-join free conjunctive queries.

We investigate trade-offs in static and dynamic evaluation of hierarchical queries with arbitrary free variables. In the static setting, the trade-off is between the time to partially compute the query result and the delay needed to enumerate its tuples. In the dynamic setting, we additionally consider the time needed to update the query result under single-tuple inserts or deletes to the database. Our approach observes the degree of values in the database and uses different computation and maintenance strategies for high-degree (heavy) and low-degree (light) values. For the latter it partially computes the result, while for the former it computes enough information to allow for on-the-fly enumeration. We define the preprocessing time, the update time, and the enumeration delay as functions of the light/heavy threshold. By appropriately choosing this threshold, our approach recovers a number of prior results when restricted to hierarchical queries. We show that for a restricted class of hierarchical queries, our approach achieves worst-case optimal update time and enumeration delay conditioned on the Online Matrix-Vector Multiplication Conjecture.

In many stochastic service systems, decision-makers find themselves making a sequence of decisions, with the number of decisions being unpredictable. To enhance these decisions, it is crucial to uncover the causal impact these decisions have through careful analysis of observational data from the system. However, these decisions are not made independently, as they are shaped by previous decisions and outcomes. This phenomenon is called sequential bias and violates a key assumption in causal inference that one person's decision does not interfere with the potential outcomes of another. To address this issue, we establish a connection between sequential bias and the subfield of causal inference known as dynamic treatment regimes. We expand these frameworks to account for the random number of decisions by modeling the decision-making process as a marked point process. Consequently, we can define and identify causal effects to quantify sequential bias. Moreover, we propose estimators and explore their properties, including double robustness and semiparametric efficiency. In a case study of 27,831 encounters with a large academic emergency department, we use our approach to demonstrate that the decision to route a patient to an area for low acuity patients has a significant impact on the care of future patients.

The widespread use of maximum Jeffreys'-prior penalized likelihood in binomial-response generalized linear models, and in logistic regression, in particular, are supported by the results of Kosmidis and Firth (2021, Biometrika), who show that the resulting estimates are also always finite-valued, even in cases where the maximum likelihood estimates are not, which is a practical issue regardless of the size of the data set. In logistic regression, the implied adjusted score equations are formally bias-reducing in asymptotic frameworks with a fixed number of parameters and appear to deliver a substantial reduction in the persistent bias of the maximum likelihood estimator in high-dimensional settings where the number of parameters grows asymptotically linearly and slower than the number of observations. In this work, we develop and present two new variants of iteratively reweighted least squares for estimating generalized linear models with adjusted score equations for mean bias reduction and maximization of the likelihood penalized by a positive power of the Jeffreys-prior penalty, which eliminate the requirement of storing $O(n)$ quantities in memory, and can operate with data sets that exceed computer memory or even hard drive capacity. We achieve that through incremental QR decompositions, which enable IWLS iterations to have access only to data chunks of predetermined size. We assess the procedures through a real-data application with millions of observations, and in high-dimensional logistic regression, where a large-scale simulation experiment produces concrete evidence for the existence of a simple adjustment to the maximum Jeffreys'-penalized likelihood estimates that delivers high accuracy in terms of signal recovery even in cases where estimates from ML and other recently-proposed corrective methods do not exist.

We introduce a physics-driven deep latent variable model (PDDLVM) to learn simultaneously parameter-to-solution (forward) and solution-to-parameter (inverse) maps of parametric partial differential equations (PDEs). Our formulation leverages conventional PDE discretization techniques, deep neural networks, probabilistic modelling, and variational inference to assemble a fully probabilistic coherent framework. In the posited probabilistic model, both the forward and inverse maps are approximated as Gaussian distributions with a mean and covariance parameterized by deep neural networks. The PDE residual is assumed to be an observed random vector of value zero, hence we model it as a random vector with a zero mean and a user-prescribed covariance. The model is trained by maximizing the probability, that is the evidence or marginal likelihood, of observing a residual of zero by maximizing the evidence lower bound (ELBO). Consequently, the proposed methodology does not require any independent PDE solves and is physics-informed at training time, allowing the real-time solution of PDE forward and inverse problems after training. The proposed framework can be easily extended to seamlessly integrate observed data to solve inverse problems and to build generative models. We demonstrate the efficiency and robustness of our method on finite element discretized parametric PDE problems such as linear and nonlinear Poisson problems, elastic shells with complex 3D geometries, and time-dependent nonlinear and inhomogeneous PDEs using a physics-informed neural network (PINN) discretization. We achieve up to three orders of magnitude speed-up after training compared to traditional finite element method (FEM), while outputting coherent uncertainty estimates.

Semantic segmentation has made significant progress in recent years thanks to deep neural networks, but the common objective of generating a single segmentation output that accurately matches the image's content may not be suitable for safety-critical domains such as medical diagnostics and autonomous driving. Instead, multiple possible correct segmentation maps may be required to reflect the true distribution of annotation maps. In this context, stochastic semantic segmentation methods must learn to predict conditional distributions of labels given the image, but this is challenging due to the typically multimodal distributions, high-dimensional output spaces, and limited annotation data. To address these challenges, we propose a conditional categorical diffusion model (CCDM) for semantic segmentation based on Denoising Diffusion Probabilistic Models. Our model is conditioned to the input image, enabling it to generate multiple segmentation label maps that account for the aleatoric uncertainty arising from divergent ground truth annotations. Our experimental results show that CCDM achieves state-of-the-art performance on LIDC, a stochastic semantic segmentation dataset, and outperforms established baselines on the classical segmentation dataset Cityscapes.

Bayesian model comparison (BMC) offers a principled approach for assessing the relative merits of competing computational models and propagating uncertainty into model selection decisions. However, BMC is often intractable for the popular class of hierarchical models due to their high-dimensional nested parameter structure. To address this intractability, we propose a deep learning method for performing BMC on any set of hierarchical models which can be instantiated as probabilistic programs. Since our method enables amortized inference, it allows efficient re-estimation of posterior model probabilities and fast performance validation prior to any real-data application. In a series of extensive validation studies, we benchmark the performance of our method against the state-of-the-art bridge sampling method and demonstrate excellent amortized inference across all BMC settings. We then showcase our method by comparing four hierarchical evidence accumulation models that have previously been deemed intractable for BMC due to partly implicit likelihoods. In this application, we corroborate evidence for the recently proposed L\'evy flight model of decision-making and show how transfer learning can be leveraged to enhance training efficiency. We provide reproducible code for all analyses and an open-source implementation of our method.

Self-supervised learning (SSL) has recently achieved impressive performance on various time series tasks. The most prominent advantage of SSL is that it reduces the dependence on labeled data. Based on the pre-training and fine-tuning strategy, even a small amount of labeled data can achieve high performance. Compared with many published self-supervised surveys on computer vision and natural language processing, a comprehensive survey for time series SSL is still missing. To fill this gap, we review current state-of-the-art SSL methods for time series data in this article. To this end, we first comprehensively review existing surveys related to SSL and time series, and then provide a new taxonomy of existing time series SSL methods. We summarize these methods into three categories: generative-based, contrastive-based, and adversarial-based. All methods can be further divided into ten subcategories. To facilitate the experiments and validation of time series SSL methods, we also summarize datasets commonly used in time series forecasting, classification, anomaly detection, and clustering tasks. Finally, we present the future directions of SSL for time series analysis.

When is heterogeneity in the composition of an autonomous robotic team beneficial and when is it detrimental? We investigate and answer this question in the context of a minimally viable model that examines the role of heterogeneous speeds in perimeter defense problems, where defenders share a total allocated speed budget. We consider two distinct problem settings and develop strategies based on dynamic programming and on local interaction rules. We present a theoretical analysis of both approaches and our results are extensively validated using simulations. Interestingly, our results demonstrate that the viability of heterogeneous teams depends on the amount of information available to the defenders. Moreover, our results suggest a universality property: across a wide range of problem parameters the optimal ratio of the speeds of the defenders remains nearly constant.

Data transmission between two or more digital devices in industry and government demands secure and agile technology. Digital information distribution often requires deployment of Internet of Things (IoT) devices and Data Fusion techniques which have also gained popularity in both, civilian and military environments, such as, emergence of Smart Cities and Internet of Battlefield Things (IoBT). This usually requires capturing and consolidating data from multiple sources. Because datasets do not necessarily originate from identical sensors, fused data typically results in a complex Big Data problem. Due to potentially sensitive nature of IoT datasets, Blockchain technology is used to facilitate secure sharing of IoT datasets, which allows digital information to be distributed, but not copied. However, blockchain has several limitations related to complexity, scalability, and excessive energy consumption. We propose an approach to hide information (sensor signal) by transforming it to an image or an audio signal. In one of the latest attempts to the military modernization, we investigate sensor fusion approach by investigating the challenges of enabling an intelligent identification and detection operation and demonstrates the feasibility of the proposed Deep Learning and Anomaly Detection models that can support future application for specific hand gesture alert system from wearable devices.

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