Social determinants of health (SDoH) have an important impact on patient outcomes but are incompletely collected from the electronic health records (EHR). This study researched the ability of large language models to extract SDoH from free text in EHRs, where they are most commonly documented, and explored the role of synthetic clinical text for improving the extraction of these scarcely documented, yet extremely valuable, clinical data. 800 patient notes were annotated for SDoH categories, and several transformer-based models were evaluated. The study also experimented with synthetic data generation and assessed for algorithmic bias. Our best-performing models were fine-tuned Flan-T5 XL (macro-F1 0.71) for any SDoH, and Flan-T5 XXL (macro-F1 0.70). The benefit of augmenting fine-tuning with synthetic data varied across model architecture and size, with smaller Flan-T5 models (base and large) showing the greatest improvements in performance (delta F1 +0.12 to +0.23). Model performance was similar on the in-hospital system dataset but worse on the MIMIC-III dataset. Our best-performing fine-tuned models outperformed zero- and few-shot performance of ChatGPT-family models for both tasks. These fine-tuned models were less likely than ChatGPT to change their prediction when race/ethnicity and gender descriptors were added to the text, suggesting less algorithmic bias (p<0.05). At the patient-level, our models identified 93.8% of patients with adverse SDoH, while ICD-10 codes captured 2.0%. Our method can effectively extracted SDoH information from clinic notes, performing better compare to GPT zero- and few-shot settings. These models could enhance real-world evidence on SDoH and aid in identifying patients needing social support.
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ACM/IEEE第23屆模型驅動工程語言和系統國際會議，是模型驅動軟件和系統工程的首要會議系列，由ACM-SIGSOFT和IEEE-TCSE支持組織。自1998年以來，模型涵蓋了建模的各個方面，從語言和方法到工具和應用程序。模特的參加者來自不同的背景，包括研究人員、學者、工程師和工業專業人士。MODELS 2019是一個論壇，參與者可以圍繞建模和模型驅動的軟件和系統交流前沿研究成果和創新實踐經驗。今年的版本將為建模社區提供進一步推進建模基礎的機會，并在網絡物理系統、嵌入式系統、社會技術系統、云計算、大數據、機器學習、安全、開源等新興領域提出建模的創新應用以及可持續性。
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Estimating the joint effect of a multivariate, continuous exposure is crucial, particularly in environmental health where interest lies in simultaneously evaluating the impact of multiple environmental pollutants on health. We develop novel methodology that addresses two key issues for estimation of treatment effects of multivariate, continuous exposures. We use nonparametric Bayesian methodology that is flexible to ensure our approach can capture a wide range of data generating processes. Additionally, we allow the effect of the exposures to be heterogeneous with respect to covariates. Treatment effect heterogeneity has not been well explored in the causal inference literature for multivariate, continuous exposures, and therefore we introduce novel estimands that summarize the nature and extent of the heterogeneity, and propose estimation procedures for new estimands related to treatment effect heterogeneity. We provide theoretical support for the proposed models in the form of posterior contraction rates and show that it works well in simulated examples both with and without heterogeneity. We apply our approach to a study of the health effects of simultaneous exposure to the components of PM$_{2.5}$ and find that the negative health effects of exposure to these environmental pollutants is exacerbated by low socioeconomic status and age.
Learning the skill of human bimanual grasping can extend the capabilities of robotic systems when grasping large or heavy objects. However, it requires a much larger search space for grasp points than single-hand grasping and numerous bimanual grasping annotations for network learning, making both data-driven or analytical grasping methods inefficient and insufficient. We propose a framework for bimanual grasp saliency learning that aims to predict the contact points for bimanual grasping based on existing human single-handed grasping data. We learn saliency corresponding vectors through minimal bimanual contact annotations that establishes correspondences between grasp positions of both hands, capable of eliminating the need for training a large-scale bimanual grasp dataset. The existing single-handed grasp saliency value serves as the initial value for bimanual grasp saliency, and we learn a saliency adjusted score that adds the initial value to obtain the final bimanual grasp saliency value, capable of predicting preferred bimanual grasp positions from single-handed grasp saliency. We also introduce a physics-balance loss function and a physics-aware refinement module that enables physical grasp balance, capable of enhancing the generalization of unknown objects. Comprehensive experiments in simulation and comparisons on dexterous grippers have demonstrated that our method can achieve balanced bimanual grasping effectively.
We describe how hierarchical concepts can be represented in three types of layered neural networks. The aim is to support recognition of the concepts when partial information about the concepts is presented, and also when some of the neurons in the network might fail. Our failure model involves initial random failures. The three types of networks are: feed-forward networks with high connectivity, feed-forward networks with low connectivity, and layered networks with low connectivity and with both forward edges and "lateral" edges within layers. In order to achieve fault-tolerance, the representations all use multiple representative neurons for each concept. We show how recognition can work in all three of these settings, and quantify how the probability of correct recognition depends on several parameters, including the number of representatives and the neuron failure probability. We also discuss how these representations might be learned, in all three types of networks. For the feed-forward networks, the learning algorithms are similar to ones used in [4], whereas for networks with lateral edges, the algorithms are generally inspired by work on the assembly calculus [3, 6, 7].
Generating proofs of unsatisfiability is a valuable capability of most SAT solvers, and is an active area of research for SMT solvers. This paper introduces the first method to efficiently generate proofs of unsatisfiability specifically for an important subset of SMT: SAT Modulo Monotonic Theories (SMMT), which includes many useful finite-domain theories (e.g., bit vectors and many graph-theoretic properties) and is used in production at Amazon Web Services. Our method uses propositional definitions of the theory predicates, from which it generates compact Horn approximations of the definitions, which lead to efficient DRAT proofs, leveraging the large investment the SAT community has made in DRAT. In experiments on practical SMMT problems, our proof generation overhead is minimal (7.41% geometric mean slowdown, 28.8% worst-case), and we can generate and check proofs for many problems that were previously intractable.
Research organisations and their research outputs have been growing considerably in the past decades. This large body of knowledge attracts various stakeholders, e.g., for knowledge sharing, technology transfer, or potential collaborations. However, due to the large amount of complex knowledge created, traditional methods of manually curating catalogues are often out of time, imprecise, and cumbersome. Finding domain experts and knowledge within any larger organisation, scientific and also industrial, has thus become a serious challenge. Hence, exploring an institutions domain knowledge and finding its experts can only be solved by an automated solution. This work presents the scheme of an automated approach for identifying scholarly experts based on their publications and, prospectively, their teaching materials. Based on a search engine, this approach is currently being implemented for two universities, for which some examples are presented. The proposed system will be helpful for finding peer researchers as well as starting points for knowledge exploitation and technology transfer. As the system is designed in a scalable manner, it can easily include additional institutions and hence provide a broader coverage of research facilities in the future.
Graph neural networks (GNNs) have been demonstrated to be a powerful algorithmic model in broad application fields for their effectiveness in learning over graphs. To scale GNN training up for large-scale and ever-growing graphs, the most promising solution is distributed training which distributes the workload of training across multiple computing nodes. However, the workflows, computational patterns, communication patterns, and optimization techniques of distributed GNN training remain preliminarily understood. In this paper, we provide a comprehensive survey of distributed GNN training by investigating various optimization techniques used in distributed GNN training. First, distributed GNN training is classified into several categories according to their workflows. In addition, their computational patterns and communication patterns, as well as the optimization techniques proposed by recent work are introduced. Second, the software frameworks and hardware platforms of distributed GNN training are also introduced for a deeper understanding. Third, distributed GNN training is compared with distributed training of deep neural networks, emphasizing the uniqueness of distributed GNN training. Finally, interesting issues and opportunities in this field are discussed.
In pace with developments in the research field of artificial intelligence, knowledge graphs (KGs) have attracted a surge of interest from both academia and industry. As a representation of semantic relations between entities, KGs have proven to be particularly relevant for natural language processing (NLP), experiencing a rapid spread and wide adoption within recent years. Given the increasing amount of research work in this area, several KG-related approaches have been surveyed in the NLP research community. However, a comprehensive study that categorizes established topics and reviews the maturity of individual research streams remains absent to this day. Contributing to closing this gap, we systematically analyzed 507 papers from the literature on KGs in NLP. Our survey encompasses a multifaceted review of tasks, research types, and contributions. As a result, we present a structured overview of the research landscape, provide a taxonomy of tasks, summarize our findings, and highlight directions for future work.
Understanding causality helps to structure interventions to achieve specific goals and enables predictions under interventions. With the growing importance of learning causal relationships, causal discovery tasks have transitioned from using traditional methods to infer potential causal structures from observational data to the field of pattern recognition involved in deep learning. The rapid accumulation of massive data promotes the emergence of causal search methods with brilliant scalability. Existing summaries of causal discovery methods mainly focus on traditional methods based on constraints, scores and FCMs, there is a lack of perfect sorting and elaboration for deep learning-based methods, also lacking some considers and exploration of causal discovery methods from the perspective of variable paradigms. Therefore, we divide the possible causal discovery tasks into three types according to the variable paradigm and give the definitions of the three tasks respectively, define and instantiate the relevant datasets for each task and the final causal model constructed at the same time, then reviews the main existing causal discovery methods for different tasks. Finally, we propose some roadmaps from different perspectives for the current research gaps in the field of causal discovery and point out future research directions.
Artificial intelligence (AI) has become a part of everyday conversation and our lives. It is considered as the new electricity that is revolutionizing the world. AI is heavily invested in both industry and academy. However, there is also a lot of hype in the current AI debate. AI based on so-called deep learning has achieved impressive results in many problems, but its limits are already visible. AI has been under research since the 1940s, and the industry has seen many ups and downs due to over-expectations and related disappointments that have followed. The purpose of this book is to give a realistic picture of AI, its history, its potential and limitations. We believe that AI is a helper, not a ruler of humans. We begin by describing what AI is and how it has evolved over the decades. After fundamentals, we explain the importance of massive data for the current mainstream of artificial intelligence. The most common representations for AI, methods, and machine learning are covered. In addition, the main application areas are introduced. Computer vision has been central to the development of AI. The book provides a general introduction to computer vision, and includes an exposure to the results and applications of our own research. Emotions are central to human intelligence, but little use has been made in AI. We present the basics of emotional intelligence and our own research on the topic. We discuss super-intelligence that transcends human understanding, explaining why such achievement seems impossible on the basis of present knowledge,and how AI could be improved. Finally, a summary is made of the current state of AI and what to do in the future. In the appendix, we look at the development of AI education, especially from the perspective of contents at our own university.
We consider the problem of explaining the predictions of graph neural networks (GNNs), which otherwise are considered as black boxes. Existing methods invariably focus on explaining the importance of graph nodes or edges but ignore the substructures of graphs, which are more intuitive and human-intelligible. In this work, we propose a novel method, known as SubgraphX, to explain GNNs by identifying important subgraphs. Given a trained GNN model and an input graph, our SubgraphX explains its predictions by efficiently exploring different subgraphs with Monte Carlo tree search. To make the tree search more effective, we propose to use Shapley values as a measure of subgraph importance, which can also capture the interactions among different subgraphs. To expedite computations, we propose efficient approximation schemes to compute Shapley values for graph data. Our work represents the first attempt to explain GNNs via identifying subgraphs explicitly and directly. Experimental results show that our SubgraphX achieves significantly improved explanations, while keeping computations at a reasonable level.
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