High-dimensional multinomial regression models are very useful in practice but receive less research attention than logistic regression models, especially from the perspective of statistical inference. In this work, we analyze the estimation and prediction error of the contrast-based $\ell_1$-penalized multinomial regression model and extend the debiasing method to the multinomial case, which provides a valid confidence interval for each coefficient and $p$-value of the individual hypothesis test. We apply the debiasing method to identify some important predictors in the progression into dementia of different subtypes. Results of intensive simulations show the superiority of the debiasing method compared to some other inference methods.
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We consider two-step estimation of latent variable models, in which just the measurement model is estimated in the first step and the measurement parameters are then fixed at their estimated values in the second step where the structural model is estimated. We show how this approach can be implemented for latent trait models (item response theory models) where the latent variables are continuous and their measurement indicators are categorical variables. The properties of two-step estimators are examined using simulation studies and applied examples. They perform well, and have attractive practical and conceptual properties compared to the alternative one-step and three-step approaches. These results are in line with previous findings for other families of latent variable models. This provides strong evidence that two-step estimation is a flexible and useful general method of estimation for different types of latent variable models.
The goal of a learning algorithm is to receive a training data set as input and provide a hypothesis that can generalize to all possible data points from a domain set. The hypothesis is chosen from hypothesis classes with potentially different complexities. Linear regression modeling is an important category of learning algorithms. The practical uncertainty of the target samples affects the generalization performance of the learned model. Failing to choose a proper model or hypothesis class can lead to serious issues such as underfitting or overfitting. These issues have been addressed by alternating cost functions or by utilizing cross-validation methods. These approaches can introduce new hyperparameters with their own new challenges and uncertainties or increase the computational complexity of the learning algorithm. On the other hand, the theory of probably approximately correct (PAC) aims at defining learnability based on probabilistic settings. Despite its theoretical value, PAC does not address practical learning issues on many occasions. This work is inspired by the foundation of PAC and is motivated by the existing regression learning issues. The proposed approach, denoted by epsilon-Confidence Approximately Correct (epsilon CoAC), utilizes Kullback Leibler divergence (relative entropy) and proposes a new related typical set in the set of hyperparameters to tackle the learnability issue. Moreover, it enables the learner to compare hypothesis classes of different complexity orders and choose among them the optimum with the minimum epsilon in the epsilon CoAC framework. Not only the epsilon CoAC learnability overcomes the issues of overfitting and underfitting, but it also shows advantages and superiority over the well known cross-validation method in the sense of time consumption as well as in the sense of accuracy.
The estimation of the generalization error of classifiers often relies on a validation set. Such a set is hardly available in few-shot learning scenarios, a highly disregarded shortcoming in the field. In these scenarios, it is common to rely on features extracted from pre-trained neural networks combined with distance-based classifiers such as nearest class mean. In this work, we introduce a Gaussian model of the feature distribution. By estimating the parameters of this model, we are able to predict the generalization error on new classification tasks with few samples. We observe that accurate distance estimates between class-conditional densities are the key to accurate estimates of the generalization performance. Therefore, we propose an unbiased estimator for these distances and integrate it in our numerical analysis. We empirically show that our approach outperforms alternatives such as the leave-one-out cross-validation strategy.
Preferential Bayesian optimization (PBO) is a framework for optimizing a decision maker's latent utility function using preference feedback. This work introduces the expected utility of the best option (qEUBO) as a novel acquisition function for PBO. When the decision maker's responses are noise-free, we show that qEUBO is one-step Bayes optimal and thus equivalent to the popular knowledge gradient acquisition function. We also show that qEUBO enjoys an additive constant approximation guarantee to the one-step Bayes-optimal policy when the decision maker's responses are corrupted by noise. We provide an extensive evaluation of qEUBO and demonstrate that it outperforms the state-of-the-art acquisition functions for PBO across many settings. Finally, we show that, under sufficient regularity conditions, qEUBO's Bayesian simple regret converges to zero at a rate $o(1/n)$ as the number of queries, $n$, goes to infinity. In contrast, we show that simple regret under qEI, a popular acquisition function for standard BO often used for PBO, can fail to converge to zero. Enjoying superior performance, simple computation, and a grounded decision-theoretic justification, qEUBO is a promising acquisition function for PBO.
We consider identification and inference for the average treatment effect and heterogeneous treatment effect conditional on observable covariates in the presence of unmeasured confounding. Since point identification of these treatment effects is not achievable without strong assumptions, we obtain bounds on these treatment effects by leveraging differential effects, a tool that allows for using a second treatment to learn the effect of the first treatment. The differential effect is the effect of using one treatment in lieu of the other. We provide conditions under which differential treatment effects can be used to point identify or partially identify treatment effects. Under these conditions, we develop a flexible and easy-to-implement semi-parametric framework to estimate bounds and establish asymptotic properties over the support for conducting statistical inference. The proposed method is examined through a simulation study and two case studies that investigate the effect of smoking on the blood level of lead and cadmium using the National Health and Nutrition Examination Survey, and the effect of soft drink consumption on the occurrence of physical fights in teenagers using the Youth Risk Behavior Surveillance System.
Kernel smoothers are essential tools for data analysis due to their ability to convey complex statistical information with concise graphical visualisations. Their inclusion in the base distribution and in the many user-contributed add-on packages of the R statistical analysis environment caters well to many practitioners. Though there remain some important gaps for specialised data types, most notably for tibbles (tidy data) within the tidyverse, and for simple features (geospatial data) within geospatial analysis. The proposed eks package fills in these gaps. In addition to kernel density estimation, this package also caters for more complex data analysis situations, such as density derivative estimation, density-based classification (supervised learning) and mean shift clustering (unsupervised learning). We illustrate with experimental data how to obtain and to interpret the statistical visualisations for these kernel smoothing methods.
Understanding variable dependence, particularly eliciting their statistical properties given a set of covariates, provides the mathematical foundation in practical operations management such as risk analysis and decision making given observed circumstances. This article presents an estimation method for modeling the conditional joint distribution of bivariate outcomes based on the distribution regression and factorization methods. This method is considered semiparametric in that it allows for flexible modeling of both the marginal and joint distributions conditional on covariates without imposing global parametric assumptions across the entire distribution. In contrast to existing parametric approaches, our method can accommodate discrete, continuous, or mixed variables, and provides a simple yet effective way to capture distributional dependence structures between bivariate outcomes and covariates. Various simulation results confirm that our method can perform similarly or better in finite samples compared to the alternative methods. In an application to the study of a motor third-part liability insurance portfolio, the proposed method effectively estimates risk measures such as the conditional Value-at-Risks and Expexted Sortfall. This result suggests that this semiparametric approach can serve as an alternative in insurance risk management.
This paper proposes three new approaches for additive functional regression models with functional responses. The first one is a reformulation of the linear regression model, and the last two are on the yet scarce case of additive nonlinear functional regression models. Both proposals are based on extensions of similar models for scalar responses. One of our nonlinear models is based on constructing a Spectral Additive Model (the word "Spectral" refers to the representation of the covariates in an $\mcal{L}_2$ basis), which is restricted (by construction) to Hilbertian spaces. The other one extends the kernel estimator, and it can be applied to general metric spaces since it is only based on distances. We include our new approaches as well as real datasets in an R package. The performances of the new proposals are compared with previous ones, which we review theoretically and practically in this paper. The simulation results show the advantages of the nonlinear proposals and the small loss of efficiency when the simulation scenario is truly linear. Finally, the supplementary material provides a visualization tool for checking the linearity of the relationship between a single covariate and the response.
Informative cluster size (ICS) arises in situations with clustered data where a latent relationship exists between the number of participants in a cluster and the outcome measures. Although this phenomenon has been sporadically reported in statistical literature for nearly two decades now, further exploration is needed in certain statistical methodologies to avoid potentially misleading inferences. For inference about population quantities without covariates, inverse cluster size reweightings are often employed to adjust for ICS. Further, to study the effect of covariates on disease progression described by a multistate model, the pseudo-value regression technique has gained popularity in time-to-event data analysis. We seek to answer the question: "How to apply pseudo-value regression to clustered time-to-event data when cluster size is informative?" ICS adjustment by the reweighting method can be performed in two steps; estimation of marginal functions of the multistate model and fitting the estimating equations based on pseudo-value responses, leading to four possible strategies. We present theoretical arguments and thorough simulation experiments to ascertain the correct strategy for adjusting for ICS. A further extension of our methodology is implemented to include informativeness induced by the intra-cluster group size. We demonstrate the methods in two real-world applications: (i) to determine predictors of tooth survival in a periodontal study, and (ii) to identify indicators of ambulatory recovery in spinal cord injury patients who participated in locomotor-training rehabilitation.
Since the 1950s, machine translation (MT) has become one of the important tasks of AI and development, and has experienced several different periods and stages of development, including rule-based methods, statistical methods, and recently proposed neural network-based learning methods. Accompanying these staged leaps is the evaluation research and development of MT, especially the important role of evaluation methods in statistical translation and neural translation research. The evaluation task of MT is not only to evaluate the quality of machine translation, but also to give timely feedback to machine translation researchers on the problems existing in machine translation itself, how to improve and how to optimise. In some practical application fields, such as in the absence of reference translations, the quality estimation of machine translation plays an important role as an indicator to reveal the credibility of automatically translated target languages. This report mainly includes the following contents: a brief history of machine translation evaluation (MTE), the classification of research methods on MTE, and the the cutting-edge progress, including human evaluation, automatic evaluation, and evaluation of evaluation methods (meta-evaluation). Manual evaluation and automatic evaluation include reference-translation based and reference-translation independent participation; automatic evaluation methods include traditional n-gram string matching, models applying syntax and semantics, and deep learning models; evaluation of evaluation methods includes estimating the credibility of human evaluations, the reliability of the automatic evaluation, the reliability of the test set, etc. Advances in cutting-edge evaluation methods include task-based evaluation, using pre-trained language models based on big data, and lightweight optimisation models using distillation techniques.
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