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The detailed clinical records drafted by doctors after each patient's visit are crucial for medical practitioners and researchers. Automating the creation of these notes with language models can reduce the workload of doctors. However, training such models can be difficult due to the limited public availability of conversations between patients and doctors. In this paper, we introduce NoteChat, a cooperative multi-agent framework leveraging Large Language Models (LLMs) for generating synthetic doctor-patient conversations conditioned on clinical notes. NoteChat consists of Planning, Roleplay, and Polish modules. We provide a comprehensive automatic and human evaluation of NoteChat, comparing it with state-of-the-art models, including OpenAI's ChatGPT and GPT-4. Results demonstrate that NoteChat facilitates high-quality synthetic doctor-patient conversations, underscoring the untapped potential of LLMs in healthcare. This work represents the first instance of multiple LLMs cooperating to complete a doctor-patient conversation conditioned on clinical notes, offering promising avenues for the intersection of AI and healthcare

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ACM/IEEE第23屆模型驅動工程語言和系統國際會議,是模型驅動軟件和系統工程的首要會議系列,由ACM-SIGSOFT和IEEE-TCSE支持組織。自1998年以來,模型涵蓋了建模的各個方面,從語言和方法到工具和應用程序。模特的參加者來自不同的背景,包括研究人員、學者、工程師和工業專業人士。MODELS 2019是一個論壇,參與者可以圍繞建模和模型驅動的軟件和系統交流前沿研究成果和創新實踐經驗。今年的版本將為建模社區提供進一步推進建模基礎的機會,并在網絡物理系統、嵌入式系統、社會技術系統、云計算、大數據、機器學習、安全、開源等新興領域提出建模的創新應用以及可持續性。 官網鏈接: · 可理解性 · Analysis · CASE · contrastive ·
2023 年 12 月 11 日

Understanding patient experience in healthcare is increasingly important and desired by medical professionals in a patient-centered care approach. Healthcare discourse on social media presents an opportunity to gain a unique perspective on patient-reported experiences, complementing traditional survey data. These social media reports often appear as first-hand accounts of patients' journeys through the healthcare system, whose details extend beyond the confines of structured surveys and at a far larger scale than focus groups. However, in contrast with the vast presence of patient-experience data on social media and the potential benefits the data offers, it attracts comparatively little research attention due to the technical proficiency required for text analysis. In this paper, we introduce the Design-Acquire-Process-Model-Analyse-Visualise (DAPMAV) framework to provide an overview of techniques and an approach to capture patient-reported experiences from social media data. We apply this framework in a case study on prostate cancer data from /r/ProstateCancer, demonstrate the framework's value in capturing specific aspects of patient concern (such as sexual dysfunction), provide an overview of the discourse, and show narrative and emotional progression through these stories. We anticipate this framework to apply to a wide variety of areas in healthcare, including capturing and differentiating experiences across minority groups, geographic boundaries, and types of illnesses.

The conventional pretraining-and-finetuning paradigm, while effective for common diseases with ample data, faces challenges in diagnosing data-scarce occupational diseases like pneumoconiosis. Recently, large language models (LLMs) have exhibits unprecedented ability when conducting multiple tasks in dialogue, bringing opportunities to diagnosis. A common strategy might involve using adapter layers for vision-language alignment and diagnosis in a dialogic manner. Yet, this approach often requires optimization of extensive learnable parameters in the text branch and the dialogue head, potentially diminishing the LLMs' efficacy, especially with limited training data. In our work, we innovate by eliminating the text branch and substituting the dialogue head with a classification head. This approach presents a more effective method for harnessing LLMs in diagnosis with fewer learnable parameters. Furthermore, to balance the retention of detailed image information with progression towards accurate diagnosis, we introduce the contextual multi-token engine. This engine is specialized in adaptively generating diagnostic tokens. Additionally, we propose the information emitter module, which unidirectionally emits information from image tokens to diagnosis tokens. Comprehensive experiments validate the superiority of our methods and the effectiveness of proposed modules. Our codes can be found at //github.com/CodeMonsterPHD/PneumoLLM/tree/main.

Digital Imaging and Communication System (DICOM) is widely used throughout the public health sector for portability in medical imaging. However, these DICOM files have vulnerabilities present in the preamble section. Successful exploitation of these vulnerabilities can allow attackers to embed executable codes in the 128-Byte preamble of DICOM files. Embedding the malicious executable will not interfere with the readability or functionality of DICOM imagery. However, it will affect the underline system silently upon viewing these files. This paper shows the infiltration of Windows malware executables into DICOM files. On viewing the files, the malicious DICOM will get executed and eventually infect the entire hospital network through the radiologist's workstation. The code injection process of executing malware in DICOM files affects the hospital networks and workstations' memory. Memory forensics for the infected radiologist's workstation is crucial as it can detect which malware disrupts the hospital environment, and future detection methods can be deployed. In this paper, we consider the machine learning (ML) algorithms to conduct memory forensics on three memory dump categories: Trojan, Spyware, and Ransomware, taken from the CIC-MalMem-2022 dataset. We obtain the highest accuracy of 75% with the Random Forest model. For estimating the feature importance for ML model prediction, we leveraged the concept of Shapley values.

The significant advancements in applying Artificial Intelligence (AI) to healthcare decision-making, medical diagnosis, and other domains have simultaneously raised concerns about the fairness and bias of AI systems. This is particularly critical in areas like healthcare, employment, criminal justice, credit scoring, and increasingly, in generative AI models (GenAI) that produce synthetic media. Such systems can lead to unfair outcomes and perpetuate existing inequalities, including generative biases that affect the representation of individuals in synthetic data. This survey paper offers a succinct, comprehensive overview of fairness and bias in AI, addressing their sources, impacts, and mitigation strategies. We review sources of bias, such as data, algorithm, and human decision biases - highlighting the emergent issue of generative AI bias where models may reproduce and amplify societal stereotypes. We assess the societal impact of biased AI systems, focusing on the perpetuation of inequalities and the reinforcement of harmful stereotypes, especially as generative AI becomes more prevalent in creating content that influences public perception. We explore various proposed mitigation strategies, discussing the ethical considerations of their implementation and emphasizing the need for interdisciplinary collaboration to ensure effectiveness. Through a systematic literature review spanning multiple academic disciplines, we present definitions of AI bias and its different types, including a detailed look at generative AI bias. We discuss the negative impacts of AI bias on individuals and society and provide an overview of current approaches to mitigate AI bias, including data pre-processing, model selection, and post-processing. We emphasize the unique challenges presented by generative AI models and the importance of strategies specifically tailored to address these.

The healthcare industry generates enormous amounts of complex clinical data that make the prediction of disease detection a complicated process. In medical informatics, making effective and efficient decisions is very important. Data Mining (DM) techniques are mainly used to identify and extract hidden patterns and interesting knowledge to diagnose and predict diseases in medical datasets. Nowadays, heart disease is considered one of the most important problems in the healthcare field. Therefore, early diagnosis leads to a reduction in deaths. DM techniques have proven highly effective for predicting and diagnosing heart diseases. This work utilizes the classification algorithms with a medical dataset of heart disease; namely, J48, Random Forest, and Na\"ive Bayes to discover the accuracy of their performance. We also examine the impact of the feature selection method. A comparative and analysis study was performed to determine the best technique using Waikato Environment for Knowledge Analysis (Weka) software, version 3.8.6. The performance of the utilized algorithms was evaluated using standard metrics such as accuracy, sensitivity and specificity. The importance of using classification techniques for heart disease diagnosis has been highlighted. We also reduced the number of attributes in the dataset, which showed a significant improvement in prediction accuracy. The results indicate that the best algorithm for predicting heart disease was Random Forest with an accuracy of 99.24%.

In pace with developments in the research field of artificial intelligence, knowledge graphs (KGs) have attracted a surge of interest from both academia and industry. As a representation of semantic relations between entities, KGs have proven to be particularly relevant for natural language processing (NLP), experiencing a rapid spread and wide adoption within recent years. Given the increasing amount of research work in this area, several KG-related approaches have been surveyed in the NLP research community. However, a comprehensive study that categorizes established topics and reviews the maturity of individual research streams remains absent to this day. Contributing to closing this gap, we systematically analyzed 507 papers from the literature on KGs in NLP. Our survey encompasses a multifaceted review of tasks, research types, and contributions. As a result, we present a structured overview of the research landscape, provide a taxonomy of tasks, summarize our findings, and highlight directions for future work.

Understanding causality helps to structure interventions to achieve specific goals and enables predictions under interventions. With the growing importance of learning causal relationships, causal discovery tasks have transitioned from using traditional methods to infer potential causal structures from observational data to the field of pattern recognition involved in deep learning. The rapid accumulation of massive data promotes the emergence of causal search methods with brilliant scalability. Existing summaries of causal discovery methods mainly focus on traditional methods based on constraints, scores and FCMs, there is a lack of perfect sorting and elaboration for deep learning-based methods, also lacking some considers and exploration of causal discovery methods from the perspective of variable paradigms. Therefore, we divide the possible causal discovery tasks into three types according to the variable paradigm and give the definitions of the three tasks respectively, define and instantiate the relevant datasets for each task and the final causal model constructed at the same time, then reviews the main existing causal discovery methods for different tasks. Finally, we propose some roadmaps from different perspectives for the current research gaps in the field of causal discovery and point out future research directions.

In contrast to batch learning where all training data is available at once, continual learning represents a family of methods that accumulate knowledge and learn continuously with data available in sequential order. Similar to the human learning process with the ability of learning, fusing, and accumulating new knowledge coming at different time steps, continual learning is considered to have high practical significance. Hence, continual learning has been studied in various artificial intelligence tasks. In this paper, we present a comprehensive review of the recent progress of continual learning in computer vision. In particular, the works are grouped by their representative techniques, including regularization, knowledge distillation, memory, generative replay, parameter isolation, and a combination of the above techniques. For each category of these techniques, both its characteristics and applications in computer vision are presented. At the end of this overview, several subareas, where continuous knowledge accumulation is potentially helpful while continual learning has not been well studied, are discussed.

Human doctors with well-structured medical knowledge can diagnose a disease merely via a few conversations with patients about symptoms. In contrast, existing knowledge-grounded dialogue systems often require a large number of dialogue instances to learn as they fail to capture the correlations between different diseases and neglect the diagnostic experience shared among them. To address this issue, we propose a more natural and practical paradigm, i.e., low-resource medical dialogue generation, which can transfer the diagnostic experience from source diseases to target ones with a handful of data for adaptation. It is capitalized on a commonsense knowledge graph to characterize the prior disease-symptom relations. Besides, we develop a Graph-Evolving Meta-Learning (GEML) framework that learns to evolve the commonsense graph for reasoning disease-symptom correlations in a new disease, which effectively alleviates the needs of a large number of dialogues. More importantly, by dynamically evolving disease-symptom graphs, GEML also well addresses the real-world challenges that the disease-symptom correlations of each disease may vary or evolve along with more diagnostic cases. Extensive experiment results on the CMDD dataset and our newly-collected Chunyu dataset testify the superiority of our approach over state-of-the-art approaches. Besides, our GEML can generate an enriched dialogue-sensitive knowledge graph in an online manner, which could benefit other tasks grounded on knowledge graph.

We propose a novel attention gate (AG) model for medical imaging that automatically learns to focus on target structures of varying shapes and sizes. Models trained with AGs implicitly learn to suppress irrelevant regions in an input image while highlighting salient features useful for a specific task. This enables us to eliminate the necessity of using explicit external tissue/organ localisation modules of cascaded convolutional neural networks (CNNs). AGs can be easily integrated into standard CNN architectures such as the U-Net model with minimal computational overhead while increasing the model sensitivity and prediction accuracy. The proposed Attention U-Net architecture is evaluated on two large CT abdominal datasets for multi-class image segmentation. Experimental results show that AGs consistently improve the prediction performance of U-Net across different datasets and training sizes while preserving computational efficiency. The code for the proposed architecture is publicly available.

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