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The lack of transparency of Deep Neural Networks continues to be a limitation that severely undermines their reliability and usage in high-stakes applications. Promising approaches to overcome such limitations are Prototype-Based Self-Explainable Neural Networks (PSENNs), whose predictions rely on the similarity between the input at hand and a set of prototypical representations of the output classes, offering therefore a deep, yet transparent-by-design, architecture. So far, such models have been designed by considering pointwise estimates for the prototypes, which remain fixed after the learning phase of the model. In this paper, we introduce a probabilistic reformulation of PSENNs, called Prob-PSENN, which replaces point estimates for the prototypes with probability distributions over their values. This provides not only a more flexible framework for an end-to-end learning of prototypes, but can also capture the explanatory uncertainty of the model, which is a missing feature in previous approaches. In addition, since the prototypes determine both the explanation and the prediction, Prob-PSENNs allow us to detect when the model is making uninformed or uncertain predictions, and to obtain valid explanations for them. Our experiments demonstrate that Prob-PSENNs provide more meaningful and robust explanations than their non-probabilistic counterparts, thus enhancing the explainability and reliability of the models.

Developing clinical prediction models (e.g., mortality prediction) based on electronic health records (EHRs) typically relies on expert opinion for feature selection and adjusting observation window size. This burdens experts and creates a bottleneck in the development process. We propose Retrieval-Enhanced Medical prediction model (REMed) to address such challenges. REMed can essentially evaluate an unlimited number of clinical events, select the relevant ones, and make predictions. This approach effectively eliminates the need for manual feature selection and enables an unrestricted observation window. We verified these properties through experiments on 27 clinical tasks and two independent cohorts from publicly available EHR datasets, where REMed outperformed other contemporary architectures that aim to handle as many events as possible. Notably, we found that the preferences of REMed align closely with those of medical experts. We expect our approach to significantly expedite the development of EHR prediction models by minimizing clinicians' need for manual involvement.

Time-optimal obstacle avoidance is a prevalent problem encountered in various fields, including robotics and autonomous vehicles, where the task involves determining a path for a moving vehicle to reach its goal while navigating around obstacles within its environment. This problem becomes increasingly challenging as the number of obstacles in the environment rises. We propose an iterative active-inactive obstacle approach, which involves identifying a subset of the obstacles as "active", that considers solely the effect of the "active" obstacles on the path of the moving vehicle. The remaining obstacles are considered "inactive" and are not considered in the path planning process. The obstacles are classified as 'active' on the basis of previous findings derived from prior iterations. This approach allows for a more efficient calculation of the optimal path by reducing the number of obstacles that need to be considered. The effectiveness of the proposed method is demonstrated with two different dynamic models using the various number of obstacles. The results show that the proposed method is able to find the optimal path in a timely manner, while also being able to handle a large number of obstacles in the environment and the constraints on the motion of the object.

Multi-Agent Path Finding (MAPF), which involves finding collision-free paths for multiple robots, is crucial in various applications. Lifelong MAPF, where targets are reassigned to agents as soon as they complete their initial objectives, offers a more accurate approximation of real-world warehouse planning. In this paper, we present a novel mechanism named Caching-Augmented Lifelong MAPF (CAL-MAPF), designed to improve the performance of Lifelong MAPF. We have developed a new map grid type called cache for temporary item storage and replacement and designed a lock mechanism for it to improve the stability of the planning solution. This cache mechanism was evaluated using various cache replacement policies and a spectrum of input task distributions. We identified three main factors significantly impacting CAL-MAPF performance through experimentation: suitable input task distribution, high cache hit rate, and smooth traffic. Overall, CAL-MAPF has demonstrated potential for performance improvements in certain task distributions, maps and agent configurations.

Calibrating robots into their workspaces is crucial for manipulation tasks. Existing calibration techniques often rely on sensors external to the robot (cameras, laser scanners, etc.) or specialized tools. This reliance complicates the calibration process and increases the costs and time requirements. Furthermore, the associated setup and measurement procedures require significant human intervention, which makes them more challenging to operate. Using the built-in force-torque sensors, which are nowadays a default component in collaborative robots, this work proposes a self-calibration framework where robot-environmental spatial relations are automatically estimated through compliant exploratory actions by the robot itself. The self-calibration approach converges, verifies its own accuracy, and terminates upon completion, autonomously purely through interactive exploration of the environment's geometries. Extensive experiments validate the effectiveness of our self-calibration approach in accurately establishing the robot-environment spatial relationships without the need for additional sensing equipment or any human intervention.

While anti-amnesia FSCIL learners often excel in incremental sessions, they tend to prioritize mitigating knowledge attrition over harnessing the model's potential for knowledge acquisition. In this paper, we delve into the foundations of model generalization in FSCIL through the lens of the Neural Tangent Kernel (NTK). Our primary design focus revolves around ensuring optimal NTK convergence and NTK-related generalization error, serving as the theoretical bedrock for exceptional generalization. To attain globally optimal NTK convergence, we employ a meta-learning mechanism grounded in mathematical principles to guide the optimization process within an expanded network. Furthermore, to reduce the NTK-related generalization error, we commence from the foundational level, optimizing the relevant factors constituting its generalization loss. Specifically, we initiate self-supervised pre-training on the base session to shape the initial network weights. Then they are carefully refined through curricular alignment, followed by the application of dual NTK regularization tailored specifically for both convolutional and linear layers. Through the combined effects of these measures, our network acquires robust NTK properties, significantly enhancing its foundational generalization. On popular FSCIL benchmark datasets, our NTK-FSCIL surpasses contemporary state-of-the-art approaches, elevating end-session accuracy by 2.9% to 8.7%.

Histo-genomic multi-modal methods have recently emerged as a powerful paradigm, demonstrating significant potential for improving cancer prognosis. However, genome sequencing, unlike histopathology imaging, is still not widely accessible in underdeveloped regions, limiting the application of these multi-modal approaches in clinical settings. To address this, we propose a novel Genome-informed Hyper-Attention Network, termed G-HANet, which is capable of effectively distilling the histo-genomic knowledge during training to elevate uni-modal whole slide image (WSI)-based inference for the first time. Compared with traditional knowledge distillation methods (i.e., teacher-student architecture) in other tasks, our end-to-end model is superior in terms of training efficiency and learning cross-modal interactions. Specifically, the network comprises the cross-modal associating branch (CAB) and hyper-attention survival branch (HSB). Through the genomic data reconstruction from WSIs, CAB effectively distills the associations between functional genotypes and morphological phenotypes and offers insights into the gene expression profiles in the feature space. Subsequently, HSB leverages the distilled histo-genomic associations as well as the generated morphology-based weights to achieve the hyper-attention modeling of the patients from both histopathology and genomic perspectives to improve cancer prognosis. Extensive experiments are conducted on five TCGA benchmarking datasets and the results demonstrate that G-HANet significantly outperforms the state-of-the-art WSI-based methods and achieves competitive performance with genome-based and multi-modal methods. G-HANet is expected to be explored as a useful tool by the research community to address the current bottleneck of insufficient histo-genomic data pairing in the context of cancer prognosis and precision oncology.

The ability to predict the future trajectories of traffic participants is crucial for the safe and efficient operation of autonomous vehicles. In this paper, a diffusion-based generative model for multi-agent trajectory prediction is proposed. The model is capable of capturing the complex interactions between traffic participants and the environment, accurately learning the multimodal nature of the data. The effectiveness of the approach is assessed on large-scale datasets of real-world traffic scenarios, showing that our model outperforms several well-established methods in terms of prediction accuracy. By the incorporation of differential motion constraints on the model output, we illustrate that our model is capable of generating a diverse set of realistic future trajectories. Through the use of an interaction-aware guidance signal, we further demonstrate that the model can be adapted to predict the behavior of less cooperative agents, emphasizing its practical applicability under uncertain traffic conditions.

Image segmentation is one of the most fundamental problems in computer vision and has drawn a lot of attentions due to its vast applications in image understanding and autonomous driving. However, designing effective and efficient segmentation neural architectures is a labor-intensive process that may require lots of trials by human experts. In this paper, we address the challenge of integrating multi-head self-attention into high resolution representation CNNs efficiently, by leveraging architecture search. Manually replacing convolution layers with multi-head self-attention is non-trivial due to the costly overhead in memory to maintain high resolution. By contrast, we develop a multi-target multi-branch supernet method, which not only fully utilizes the advantages of high-resolution features, but also finds the proper location for placing multi-head self-attention module. Our search algorithm is optimized towards multiple objective s (e.g., latency and mIoU) and capable of finding architectures on Pareto frontier with arbitrary number of branches in a single search. We further present a series of model via Hybrid Convolutional-Transformer Architecture Search (HyCTAS) method that searched for the best hybrid combination of light-weight convolution layers and memory-efficient self-attention layers between branches from different resolutions and fuse to high resolution for both efficiency and effectiveness. Extensive experiments demonstrate that HyCTAS outperforms previous methods on semantic segmentation task. Code and models are available at \url{//github.com/MarvinYu1995/HyCTAS}.

In recent research, significant attention has been devoted to the open-vocabulary object detection task, aiming to generalize beyond the limited number of classes labeled during training and detect objects described by arbitrary category names at inference. Compared with conventional object detection, open vocabulary object detection largely extends the object detection categories. However, it relies on calculating the similarity between image regions and a set of arbitrary category names with a pretrained vision-and-language model. This implies that, despite its open-set nature, the task still needs the predefined object categories during the inference stage. This raises the question: What if we do not have exact knowledge of object categories during inference? In this paper, we call such a new setting as generative open-ended object detection, which is a more general and practical problem. To address it, we formulate object detection as a generative problem and propose a simple framework named GenerateU, which can detect dense objects and generate their names in a free-form way. Particularly, we employ Deformable DETR as a region proposal generator with a language model translating visual regions to object names. To assess the free-form object detection task, we introduce an evaluation method designed to quantitatively measure the performance of generative outcomes. Extensive experiments demonstrate strong zero-shot detection performance of our GenerateU. For example, on the LVIS dataset, our GenerateU achieves comparable results to the open-vocabulary object detection method GLIP, even though the category names are not seen by GenerateU during inference. Code is available at: // github.com/FoundationVision/GenerateU .