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This paper strives for self-supervised learning of a feature space suitable for skeleton-based action recognition. Our proposal is built upon learning invariances to input skeleton representations and various skeleton augmentations via a noise contrastive estimation. In particular, we propose inter-skeleton contrastive learning, which learns from multiple different input skeleton representations in a cross-contrastive manner. In addition, we contribute several skeleton-specific spatial and temporal augmentations which further encourage the model to learn the spatio-temporal dynamics of skeleton data. By learning similarities between different skeleton representations as well as augmented views of the same sequence, the network is encouraged to learn higher-level semantics of the skeleton data than when only using the augmented views. Our approach achieves state-of-the-art performance for self-supervised learning from skeleton data on the challenging PKU and NTU datasets with multiple downstream tasks, including action recognition, action retrieval and semi-supervised learning. Code is available at //github.com/fmthoker/skeleton-contrast.

Lane segmentation is a challenging issue in autonomous driving system designing because lane marks show weak textural consistency due to occlusion or extreme illumination but strong geometric continuity in traffic images, from which general convolution neural networks (CNNs) are not capable of learning semantic objects. To empower conventional CNNs in learning geometric clues of lanes, we propose a deep network named ContinuityLearner to better learn geometric prior within lane. Specifically, our proposed CNN-based paradigm involves a novel Context-encoding image feature learning network to generate class-dependent image feature maps and a new encoding layer to exploit the geometric continuity feature representation by fusing both spatial and visual information of lane together. The ContinuityLearner, performing on the geometric continuity feature of lanes, is trained to directly predict the lane in traffic scenarios with integrated and continuous instance semantic. The experimental results on the CULane dataset and the Tusimple benchmark demonstrate that our ContinuityLearner has superior performance over other state-of-the-art techniques in lane segmentation.

Contrastive Learning (CL) is a recent representation learning approach, which encourages inter-class separability and intra-class compactness in learned image representations. Since medical images often contain multiple semantic classes in an image, using CL to learn representations of local features (as opposed to global) is important. In this work, we present a novel semi-supervised 2D medical segmentation solution that applies CL on image patches, instead of full images. These patches are meaningfully constructed using the semantic information of different classes obtained via pseudo labeling. We also propose a novel consistency regularization (CR) scheme, which works in synergy with CL. It addresses the problem of confirmation bias, and encourages better clustering in the feature space. We evaluate our method on four public medical segmentation datasets and a novel histopathology dataset that we introduce. Our method obtains consistent improvements over state-of-the-art semi-supervised segmentation approaches for all datasets.

Automatic and accurate tumor segmentation on medical images is in high demand to assist physicians with diagnosis and treatment. However, it is difficult to obtain massive amounts of annotated training data required by the deep-learning models as the manual delineation process is often tedious and expertise required. Although self-supervised learning (SSL) scheme has been widely adopted to address this problem, most SSL methods focus only on global structure information, ignoring the key distinguishing features of tumor regions: local intensity variation and large size distribution. In this paper, we propose Scale-Aware Restoration (SAR), a SSL method for 3D tumor segmentation. Specifically, a novel proxy task, i.e. scale discrimination, is formulated to pre-train the 3D neural network combined with the self-restoration task. Thus, the pre-trained model learns multi-level local representations through multi-scale inputs. Moreover, an adversarial learning module is further introduced to learn modality invariant representations from multiple unlabeled source datasets. We demonstrate the effectiveness of our methods on two downstream tasks: i) Brain tumor segmentation, ii) Pancreas tumor segmentation. Compared with the state-of-the-art 3D SSL methods, our proposed approach can significantly improve the segmentation accuracy. Besides, we analyze its advantages from multiple perspectives such as data efficiency, performance, and convergence speed.

Acquiring sufficient ground-truth supervision to train deep visual models has been a bottleneck over the years due to the data-hungry nature of deep learning. This is exacerbated in some structured prediction tasks, such as semantic segmentation, which requires pixel-level annotations. This work addresses weakly supervised semantic segmentation (WSSS), with the goal of bridging the gap between image-level annotations and pixel-level segmentation. We formulate WSSS as a novel group-wise learning task that explicitly models semantic dependencies in a group of images to estimate more reliable pseudo ground-truths, which can be used for training more accurate segmentation models. In particular, we devise a graph neural network (GNN) for group-wise semantic mining, wherein input images are represented as graph nodes, and the underlying relations between a pair of images are characterized by an efficient co-attention mechanism. Moreover, in order to prevent the model from paying excessive attention to common semantics only, we further propose a graph dropout layer, encouraging the model to learn more accurate and complete object responses. The whole network is end-to-end trainable by iterative message passing, which propagates interaction cues over the images to progressively improve the performance. We conduct experiments on the popular PASCAL VOC 2012 and COCO benchmarks, and our model yields state-of-the-art performance. Our code is available at: //github.com/Lixy1997/Group-WSSS.

We consider the question: how can you sample good negative examples for contrastive learning? We argue that, as with metric learning, learning contrastive representations benefits from hard negative samples (i.e., points that are difficult to distinguish from an anchor point). The key challenge toward using hard negatives is that contrastive methods must remain unsupervised, making it infeasible to adopt existing negative sampling strategies that use label information. In response, we develop a new class of unsupervised methods for selecting hard negative samples where the user can control the amount of hardness. A limiting case of this sampling results in a representation that tightly clusters each class, and pushes different classes as far apart as possible. The proposed method improves downstream performance across multiple modalities, requires only few additional lines of code to implement, and introduces no computational overhead.

Deep learning-based semi-supervised learning (SSL) algorithms have led to promising results in medical images segmentation and can alleviate doctors' expensive annotations by leveraging unlabeled data. However, most of the existing SSL algorithms in literature tend to regularize the model training by perturbing networks and/or data. Observing that multi/dual-task learning attends to various levels of information which have inherent prediction perturbation, we ask the question in this work: can we explicitly build task-level regularization rather than implicitly constructing networks- and/or data-level perturbation-and-transformation for SSL? To answer this question, we propose a novel dual-task-consistency semi-supervised framework for the first time. Concretely, we use a dual-task deep network that jointly predicts a pixel-wise segmentation map and a geometry-aware level set representation of the target. The level set representation is converted to an approximated segmentation map through a differentiable task transform layer. Simultaneously, we introduce a dual-task consistency regularization between the level set-derived segmentation maps and directly predicted segmentation maps for both labeled and unlabeled data. Extensive experiments on two public datasets show that our method can largely improve the performance by incorporating the unlabeled data. Meanwhile, our framework outperforms the state-of-the-art semi-supervised medical image segmentation methods. Code is available at: //github.com/Luoxd1996/DTC

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to pre-train a neural network with unlabeled data, followed by fine-tuning for a downstream task with limited annotations. Contrastive learning, a particular variant of SSL, is a powerful technique for learning image-level representations. In this work, we propose strategies for extending the contrastive learning framework for segmentation of volumetric medical images in the semi-supervised setting with limited annotations, by leveraging domain-specific and problem-specific cues. Specifically, we propose (1) novel contrasting strategies that leverage structural similarity across volumetric medical images (domain-specific cue) and (2) a local version of the contrastive loss to learn distinctive representations of local regions that are useful for per-pixel segmentation (problem-specific cue). We carry out an extensive evaluation on three Magnetic Resonance Imaging (MRI) datasets. In the limited annotation setting, the proposed method yields substantial improvements compared to other self-supervision and semi-supervised learning techniques. When combined with a simple data augmentation technique, the proposed method reaches within 8% of benchmark performance using only two labeled MRI volumes for training, corresponding to only 4% (for ACDC) of the training data used to train the benchmark.

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own strengths and weaknesses, and by unifying them together, one may be able to achieve more accurate results. In this paper, we propose a new ensemble learning framework for 3D biomedical image segmentation that combines the merits of 2D and 3D models. First, we develop a fully convolutional network based meta-learner to learn how to improve the results from 2D and 3D models (base-learners). Then, to minimize over-fitting for our sophisticated meta-learner, we devise a new training method that uses the results of the base-learners as multiple versions of "ground truths". Furthermore, since our new meta-learner training scheme does not depend on manual annotation, it can utilize abundant unlabeled 3D image data to further improve the model. Extensive experiments on two public datasets (the HVSMR 2016 Challenge dataset and the mouse piriform cortex dataset) show that our approach is effective under fully-supervised, semi-supervised, and transductive settings, and attains superior performance over state-of-the-art image segmentation methods.

Medical image segmentation requires consensus ground truth segmentations to be derived from multiple expert annotations. A novel approach is proposed that obtains consensus segmentations from experts using graph cuts (GC) and semi supervised learning (SSL). Popular approaches use iterative Expectation Maximization (EM) to estimate the final annotation and quantify annotator's performance. Such techniques pose the risk of getting trapped in local minima. We propose a self consistency (SC) score to quantify annotator consistency using low level image features. SSL is used to predict missing annotations by considering global features and local image consistency. The SC score also serves as the penalty cost in a second order Markov random field (MRF) cost function optimized using graph cuts to derive the final consensus label. Graph cut obtains a global maximum without an iterative procedure. Experimental results on synthetic images, real data of Crohn's disease patients and retinal images show our final segmentation to be accurate and more consistent than competing methods.