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It is well-known that mood and pain interact with each other, however individual-level variability in this relationship has been less well quantified than overall associations between low mood and pain. Here, we leverage the possibilities presented by mobile health data, in particular the "Cloudy with a Chance of Pain" study, which collected longitudinal data from the residents of the UK with chronic pain conditions. Participants used an App to record self-reported measures of factors including mood, pain and sleep quality. The richness of these data allows us to perform model-based clustering of the data as a mixture of Markov processes. Through this analysis we discover four endotypes with distinct patterns of co-evolution of mood and pain over time. The differences between endotypes are sufficiently large to play a role in clinical hypothesis generation for personalised treatments of comorbid pain and low mood.

By abstracting over well-known properties of De Bruijn's representation with nameless dummies, we design a new theory of syntax with variable binding and capture-avoiding substitution. We propose it as a simpler alternative to Fiore, Plotkin, and Turi's approach, with which we establish a strong formal link. We also show that our theory easily incorporates simple types and equations between terms.

Laguerre spectral approximations play an important role in the development of efficient algorithms for problems in unbounded domains. In this paper, we present a comprehensive convergence rate analysis of Laguerre spectral approximations for analytic functions. By exploiting contour integral techniques from complex analysis, we prove that Laguerre projection and interpolation methods of degree $n$ converge at the root-exponential rate $O(\exp(-2\rho\sqrt{n}))$ with $\rho>0$ when the underlying function is analytic inside and on a parabola with focus at the origin and vertex at $z=-\rho^2$. As far as we know, this is the first rigorous proof of root-exponential convergence of Laguerre approximations for analytic functions. Several important applications of our analysis are also discussed, including Laguerre spectral differentiations, Gauss-Laguerre quadrature rules, the scaling factor and the Weeks method for the inversion of Laplace transform, and some sharp convergence rate estimates are derived. Numerical experiments are presented to verify the theoretical results.

In this paper we consider a nonlinear poroelasticity model that describes the quasi-static mechanical behaviour of a fluid-saturated porous medium whose permeability depends on the divergence of the displacement. Such nonlinear models are typically used to study biological structures like tissues, organs, cartilage and bones, which are known for a nonlinear dependence of their permeability/hydraulic conductivity on solid dilation. We formulate (extend to the present situation) one of the most popular splitting schemes, namely the fixed-stress split method for the iterative solution of the coupled problem. The method is proven to converge linearly for sufficiently small time steps under standard assumptions. The error contraction factor then is strictly less than one, independent of the Lam\'{e} parameters, Biot and storage coefficients if the hydraulic conductivity is a strictly positive, bounded and Lipschitz-continuous function.

Word embedding methods (WEMs) are extensively used for representing text data. The dimensionality of these embeddings varies across various tasks and implementations. The effect of dimensionality change on the accuracy of the downstream task is a well-explored question. However, how the dimensionality change affects the bias of word embeddings needs to be investigated. Using the English Wikipedia corpus, we study this effect for two static (Word2Vec and fastText) and two context-sensitive (ElMo and BERT) WEMs. We have two observations. First, there is a significant variation in the bias of word embeddings with the dimensionality change. Second, there is no uniformity in how the dimensionality change affects the bias of word embeddings. These factors should be considered while selecting the dimensionality of word embeddings.

This paper presents a time-causal analogue of the Gabor filter, as well as a both time-causal and time-recursive analogue of the Gabor transform, where the proposed time-causal representations obey both temporal scale covariance and a cascade property with a simplifying kernel over temporal scales. The motivation behind these constructions is to enable theoretically well-founded time-frequency analysis over multiple temporal scales for real-time situations, or for physical or biological modelling situations, when the future cannot be accessed, and the non-causal access to future in Gabor filtering is therefore not viable for a time-frequency analysis of the system. We develop the theory for these representations, obtained by replacing the Gaussian kernel in Gabor filtering with a time-causal kernel, referred to as the time-causal limit kernel, which guarantees simplification properties from finer to coarser levels of scales in a time-causal situation, similar as the Gaussian kernel can be shown to guarantee over a non-causal temporal domain. In these ways, the proposed time-frequency representations guarantee well-founded treatment over multiple scales, in situations when the characteristic scales in the signals, or physical or biological phenomena, to be analyzed may vary substantially, and additionally all steps in the time-frequency analysis have to be fully time-causal.

We investigate a variational method for ill-posed problems, named $\texttt{graphLa+}\Psi$, which embeds a graph Laplacian operator in the regularization term. The novelty of this method lies in constructing the graph Laplacian based on a preliminary approximation of the solution, which is obtained using any existing reconstruction method $\Psi$ from the literature. As a result, the regularization term is both dependent on and adaptive to the observed data and noise. We demonstrate that $\texttt{graphLa+}\Psi$ is a regularization method and rigorously establish both its convergence and stability properties. We present selected numerical experiments in 2D computerized tomography, wherein we integrate the $\texttt{graphLa+}\Psi$ method with various reconstruction techniques $\Psi$, including Filter Back Projection ($\texttt{graphLa+FBP}$), standard Tikhonov ($\texttt{graphLa+Tik}$), Total Variation ($\texttt{graphLa+TV}$), and a trained deep neural network ($\texttt{graphLa+Net}$). The $\texttt{graphLa+}\Psi$ approach significantly enhances the quality of the approximated solutions for each method $\Psi$. Notably, $\texttt{graphLa+Net}$ is outperforming, offering a robust and stable application of deep neural networks in solving inverse problems.

Online speech recognition, where the model only accesses context to the left, is an important and challenging use case for ASR systems. In this work, we investigate augmenting neural encoders for online ASR by incorporating structured state-space sequence models (S4), a family of models that provide a parameter-efficient way of accessing arbitrarily long left context. We performed systematic ablation studies to compare variants of S4 models and propose two novel approaches that combine them with convolutions. We found that the most effective design is to stack a small S4 using real-valued recurrent weights with a local convolution, allowing them to work complementarily. Our best model achieves WERs of 4.01%/8.53% on test sets from Librispeech, outperforming Conformers with extensively tuned convolution.

There has been recently a lot of interest in the analysis of the Stein gradient descent method, a deterministic sampling algorithm. It is based on a particle system moving along the gradient flow of the Kullback-Leibler divergence towards the asymptotic state corresponding to the desired distribution. Mathematically, the method can be formulated as a joint limit of time $t$ and number of particles $N$ going to infinity. We first observe that the recent work of Lu, Lu and Nolen (2019) implies that if $t \approx \log \log N$, then the joint limit can be rigorously justified in the Wasserstein distance. Not satisfied with this time scale, we explore what happens for larger times by investigating the stability of the method: if the particles are initially close to the asymptotic state (with distance $\approx 1/N$), how long will they remain close? We prove that this happens in algebraic time scales $t \approx \sqrt{N}$ which is significantly better. The exploited method, developed by Caglioti and Rousset for the Vlasov equation, is based on finding a functional invariant for the linearized equation. This allows to eliminate linear terms and arrive at an improved Gronwall-type estimate.

The goal of explainable Artificial Intelligence (XAI) is to generate human-interpretable explanations, but there are no computationally precise theories of how humans interpret AI generated explanations. The lack of theory means that validation of XAI must be done empirically, on a case-by-case basis, which prevents systematic theory-building in XAI. We propose a psychological theory of how humans draw conclusions from saliency maps, the most common form of XAI explanation, which for the first time allows for precise prediction of explainee inference conditioned on explanation. Our theory posits that absent explanation humans expect the AI to make similar decisions to themselves, and that they interpret an explanation by comparison to the explanations they themselves would give. Comparison is formalized via Shepard's universal law of generalization in a similarity space, a classic theory from cognitive science. A pre-registered user study on AI image classifications with saliency map explanations demonstrate that our theory quantitatively matches participants' predictions of the AI.