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We propose principled prediction intervals to quantify the uncertainty of a large class of synthetic control predictions or estimators in settings with staggered treatment adoption, offering precise non-asymptotic coverage probability guarantees. From a methodological perspective, we provide a detailed discussion of different causal quantities to be predicted, which we call `causal predictands', allowing for multiple treated units with treatment adoption at possibly different points in time. From a theoretical perspective, our uncertainty quantification methods improve on prior literature by (i) covering a large class of causal predictands in staggered adoption settings, (ii) allowing for synthetic control methods with possibly nonlinear constraints, (iii) proposing scalable robust conic optimization methods and principled data-driven tuning parameter selection, and (iv) offering valid uniform inference across post-treatment periods. We illustrate our methodology with an empirical application studying the effects of economic liberalization in the 1990s on GDP for emerging European countries. Companion general-purpose software packages are provided in Python, R and Stata.

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The prevalence and importance of algorithmic two-sided marketplaces has drawn attention to the issue of fairness in such settings. Algorithmic decisions are used in assigning students to schools, users to advertisers, and applicants to job interviews. These decisions should heed the preferences of individuals, and simultaneously be fair with respect to their merits (synonymous with fit, future performance, or need). Merits conditioned on observable features are always \emph{uncertain}, a fact that is exacerbated by the widespread use of machine learning algorithms to infer merit from the observables. As our key contribution, we carefully axiomatize a notion of individual fairness in the two-sided marketplace setting which respects the uncertainty in the merits; indeed, it simultaneously recognizes uncertainty as the primary potential cause of unfairness and an approach to address it. We design a linear programming framework to find fair utility-maximizing distributions over allocations, and we show that the linear program is robust to perturbations in the estimated parameters of the uncertain merit distributions, a key property in combining the approach with machine learning techniques.

The problem of generalization and transportation of treatment effect estimates from a study sample to a target population is central to empirical research and statistical methodology. In both randomized experiments and observational studies, weighting methods are often used with this objective. Traditional methods construct the weights by separately modeling the treatment assignment and study selection probabilities and then multiplying functions (e.g., inverses) of their estimates. In this work, we provide a justification and an implementation for weighting in a single step. We show a formal connection between this one-step method and inverse probability and inverse odds weighting. We demonstrate that the resulting estimator for the target average treatment effect is consistent, asymptotically Normal, multiply robust, and semiparametrically efficient. We evaluate the performance of the one-step estimator in a simulation study. We illustrate its use in a case study on the effects of physician racial diversity on preventive healthcare utilization among Black men in California. We provide R code implementing the methodology.

Multiple measures, such as WEAT or MAC, attempt to quantify the magnitude of bias present in word embeddings in terms of a single-number metric. However, such metrics and the related statistical significance calculations rely on treating pre-averaged data as individual data points and employing bootstrapping techniques with low sample sizes. We show that similar results can be easily obtained using such methods even if the data are generated by a null model lacking the intended bias. Consequently, we argue that this approach generates false confidence. To address this issue, we propose a Bayesian alternative: hierarchical Bayesian modeling, which enables a more uncertainty-sensitive inspection of bias in word embeddings at different levels of granularity. To showcase our method, we apply it to Religion, Gender, and Race word lists from the original research, together with our control neutral word lists. We deploy the method using Google, Glove, and Reddit embeddings. Further, we utilize our approach to evaluate a debiasing technique applied to Reddit word embedding. Our findings reveal a more complex landscape than suggested by the proponents of single-number metrics. The datasets and source code for the paper are publicly available.

This paper presents a robust version of the stratified sampling method when multiple uncertain input models are considered for stochastic simulation. Various variance reduction techniques have demonstrated their superior performance in accelerating simulation processes. Nevertheless, they often use a single input model and further assume that the input model is exactly known and fixed. We consider more general cases in which it is necessary to assess a simulation's response to a variety of input models, such as when evaluating the reliability of wind turbines under nonstationary wind conditions or the operation of a service system when the distribution of customer inter-arrival time is heterogeneous at different times. Moreover, the estimation variance may be considerably impacted by uncertainty in input models. To address such nonstationary and uncertain input models, we offer a distributionally robust (DR) stratified sampling approach with the goal of minimizing the maximum of worst-case estimator variances among plausible but uncertain input models. Specifically, we devise a bi-level optimization framework for formulating DR stochastic problems with different ambiguity set designs, based on the $L_2$-norm, 1-Wasserstein distance, parametric family of distributions, and distribution moments. In order to cope with the non-convexity of objective function, we present a solution approach that uses Bayesian optimization. Numerical experiments and the wind turbine case study demonstrate the robustness of the proposed approach.

Recently proposed Generalized Time-domain Velocity Vector (GTVV) is a generalization of relative room impulse response in spherical harmonic (aka Ambisonic) domain that allows for blind estimation of early-echo parameters: the directions and relative delays of individual reflections. However, the derived closed-form expression of GTVV mandates few assumptions to hold, most important being that the impulse response of the reference signal needs to be a minimum-phase filter. In practice, the reference is obtained by spatial filtering towards the Direction-of-Arrival of the source, and the aforementioned condition is bounded by the performance of the applied beamformer (and thus, by the Ambisonic array order). In the present work, we suggest to circumvent this problem by properly modelling the GTVV time series, which permits not only to relax the initial assumptions, but also to extract the information therein is a more consistent and efficient manner, entering the realm of blind system identification. Experiments using measured room impulse responses confirm the effectiveness of the proposed approach.

Conformalized Quantile Regression (CQR) is a recently proposed method for constructing prediction intervals for a response $Y$ given covariates $X$, without making distributional assumptions. However, as we demonstrate empirically, existing constructions of CQR can be ineffective for problems where the quantile regressors perform better in certain parts of the feature space than others. The reason is that the prediction intervals of CQR do not distinguish between two forms of uncertainty: first, the variability of the conditional distribution of $Y$ given $X$ (i.e., aleatoric uncertainty), and second, our uncertainty in estimating this conditional distribution (i.e., epistemic uncertainty). This can lead to uneven coverage, with intervals that are overly wide (or overly narrow) in regions where epistemic uncertainty is low (or high). To address this, we propose a new variant of the CQR methodology, Uncertainty-Aware CQR (UACQR), that explicitly separates these two sources of uncertainty to adjust quantile regressors differentially across the feature space. Compared to CQR, our methods enjoy the same distribution-free theoretical guarantees for coverage properties, while demonstrating in our experiments stronger conditional coverage in simulated settings and tighter intervals on a range of real-world data sets.

Learning individualized treatment rules (ITRs) is an important topic in precision medicine. Current literature mainly focuses on deriving ITRs from a single source population. We consider the observational data setting when the source population differs from a target population of interest. Compared with causal generalization for the average treatment effect which is a scalar quantity, ITR generalization poses new challenges due to the need to model and generalize the rules based on a prespecified class of functions which may not contain the unrestricted true optimal ITR. The aim of this paper is to develop a weighting framework to mitigate the impact of such misspecification and thus facilitate the generalizability of optimal ITRs from a source population to a target population. Our method seeks covariate balance over a non-parametric function class characterized by a reproducing kernel Hilbert space and can improve many ITR learning methods that rely on weights. We show that the proposed method encompasses importance weights and overlap weights as two extreme cases, allowing for a better bias-variance trade-off in between. Numerical examples demonstrate that the use of our weighting method can greatly improve ITR estimation for the target population compared with other weighting methods.

This paper presents an end-to-end framework for robust structure/control optimization of an industrial benchmark. When dealing with space structures, a reduction of the spacecraft mass is paramount to minimize the mission cost and maximize the propellant availability. However, a lighter design comes with a bigger structural flexibility and the resulting impact on control performance. Two optimization architectures (distributed and monolithic) are proposed in order to face this issue. In particular the Linear Fractional Transformation (LFT) framework is exploited to formally set the two optimization problems by including parametric uncertainties. Large sets of uncertainties have to be indeed taken into account in spacecraft control design due to the impossibility to completely validate structural models in micro-gravity conditions with on-ground experiments and to the evolution of spacecraft dynamics during the mission (structure degradation and fuel consumption). In particular the Two-Input Two-Output Port (TITOP) multi-body approach is used to build the flexible dynamics in a minimal LFT form. The two proposed optimization algorithms are detailed and their performance are compared on an ESA future exploration mission, the ENVISION benchmark. With both approaches, an important reduction of the mass is obtained by coping with the mission's control performance/stability requirements and a large set of uncertainties.

This PhD thesis contains several contributions to the field of statistical causal modeling. Statistical causal models are statistical models embedded with causal assumptions that allow for the inference and reasoning about the behavior of stochastic systems affected by external manipulation (interventions). This thesis contributes to the research areas concerning the estimation of causal effects, causal structure learning, and distributionally robust (out-of-distribution generalizing) prediction methods. We present novel and consistent linear and non-linear causal effects estimators in instrumental variable settings that employ data-dependent mean squared prediction error regularization. Our proposed estimators show, in certain settings, mean squared error improvements compared to both canonical and state-of-the-art estimators. We show that recent research on distributionally robust prediction methods has connections to well-studied estimators from econometrics. This connection leads us to prove that general K-class estimators possess distributional robustness properties. We, furthermore, propose a general framework for distributional robustness with respect to intervention-induced distributions. In this framework, we derive sufficient conditions for the identifiability of distributionally robust prediction methods and present impossibility results that show the necessity of several of these conditions. We present a new structure learning method applicable in additive noise models with directed trees as causal graphs. We prove consistency in a vanishing identifiability setup and provide a method for testing substructure hypotheses with asymptotic family-wise error control that remains valid post-selection. Finally, we present heuristic ideas for learning summary graphs of nonlinear time-series models.

Ensembles over neural network weights trained from different random initialization, known as deep ensembles, achieve state-of-the-art accuracy and calibration. The recently introduced batch ensembles provide a drop-in replacement that is more parameter efficient. In this paper, we design ensembles not only over weights, but over hyperparameters to improve the state of the art in both settings. For best performance independent of budget, we propose hyper-deep ensembles, a simple procedure that involves a random search over different hyperparameters, themselves stratified across multiple random initializations. Its strong performance highlights the benefit of combining models with both weight and hyperparameter diversity. We further propose a parameter efficient version, hyper-batch ensembles, which builds on the layer structure of batch ensembles and self-tuning networks. The computational and memory costs of our method are notably lower than typical ensembles. On image classification tasks, with MLP, LeNet, and Wide ResNet 28-10 architectures, our methodology improves upon both deep and batch ensembles.

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