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Many diseases, including cancer and chronic conditions, require extended treatment periods and long-term strategies. Machine learning and AI research focusing on electronic health records (EHRs) have emerged to address this need. Effective treatment strategies involve more than capturing sequential changes in patient test values. It requires an explainable and clinically interpretable model by capturing the patient's internal state over time. In this study, we propose the "deep state-space analysis framework," using time-series unsupervised learning of EHRs with a deep state-space model. This framework enables learning, visualizing, and clustering of temporal changes in patient latent states related to disease progression. We evaluated our framework using time-series laboratory data from 12,695 cancer patients. By estimating latent states, we successfully discover latent states related to prognosis. By visualization and cluster analysis, the temporal transition of patient status and test items during state transitions characteristic of each anticancer drug were identified. Our framework surpasses existing methods in capturing interpretable latent space. It can be expected to enhance our comprehension of disease progression from EHRs, aiding treatment adjustments and prognostic determinations.

The problem of low rank approximation is ubiquitous in science. Traditionally this problem is solved in unitary invariant norms such as Frobenius or spectral norm due to existence of efficient methods for building approximations. However, recent results reveal the potential of low rank approximations in Chebyshev norm, which naturally arises in many applications. In this paper we tackle the problem of building optimal rank-1 approximations in the Chebyshev norm. We investigate the properties of alternating minimization algorithm for building the low rank approximations and demonstrate how to use it to construct optimal rank-1 approximation. As a result we propose an algorithm that is capable of building optimal rank-1 approximations in Chebyshev norm for small matrices.

Over the years of challenges on detecting the crash consistency of non-volatile persistent memory (PM) bugs and developing new tools to identify those bugs are quite stretching due to its inconsistent behavior on the file or storage systems. In this paper, we evaluated an open-sourced automatic bug detector tool (i.e. AGAMOTTO) to test NVM level hashing PM application to identify performance and correctness PM bugs in the persistent (main) memory. Furthermore, our faithful validation tool able to discovered 65 new NVM level hashing bugs on PMDK library and it outperformed the number of bugs (i.e. 40 bugs) that WITCHER framework was able to identified. Finally, we will propose a Deep-Q Learning search heuristic algorithm over the PM-Aware search algorithm in the state selection process to improve the searching strategy efficiently.

Successful deployment of artificial intelligence (AI) in various settings has led to numerous positive outcomes for individuals and society. However, AI systems have also been shown to harm parts of the population due to biased predictions. AI fairness focuses on mitigating such biases to ensure AI decision making is not discriminatory towards certain groups. We take a closer look at AI fairness and analyze how lack of AI fairness can lead to deepening of biases over time and act as a social stressor. More specifically, we discuss how biased models can lead to more negative real-world outcomes for certain groups, which may then become more prevalent by deploying new AI models trained on increasingly biased data, resulting in a feedback loop. If the issues persist, they could be reinforced by interactions with other risks and have severe implications on society in the form of social unrest. We examine current strategies for improving AI fairness, assess their limitations in terms of real-world deployment, and explore potential paths forward to ensure we reap AI's benefits without causing society's collapse.

We study the operator norm discrepancy of i.i.d. random matrices, initiating the matrix-valued analog of a long line of work on the $\ell^{\infty}$ norm discrepancy of i.i.d. random vectors. First, we give a new analysis of the matrix hyperbolic cosine algorithm of Zouzias (2011), a matrix version of an online vector discrepancy algorithm of Spencer (1977) studied for average-case inputs by Bansal and Spencer (2020), for the case of i.i.d. random matrix inputs. We both give a general analysis and extract concrete bounds on the discrepancy achieved by this algorithm for matrices with independent entries and positive semidefinite matrices drawn from Wishart distributions. Second, using the first moment method, we give lower bounds on the discrepancy of random matrices, in particular showing that the matrix hyperbolic cosine algorithm achieves optimal discrepancy up to logarithmic terms in several cases. We both treat the special case of the Gaussian orthogonal ensemble and give a general result for low-rank matrix distributions that we apply to orthogonally invariant random projections.

Meeting the strict Quality of Service (QoS) requirements of terminals has imposed a signiffcant challenge on Multiaccess Edge Computing (MEC) systems, due to the limited multidimensional resources. To address this challenge, we propose a collaborative MEC framework that facilitates resource sharing between the edge servers, and with the aim to maximize the long-term QoS and reduce the cache switching cost through joint optimization of service caching, collaborative offfoading, and computation and communication resource allocation. The dual timescale feature and temporal recurrence relationship between service caching and other resource allocation make solving the problem even more challenging. To solve it, we propose a deep reinforcement learning (DRL)-based dual timescale scheme, called DGL-DDPG, which is composed of a short-term genetic algorithm (GA) and a long short-term memory network-based deep deterministic policy gradient (LSTM-DDPG). In doing so, we reformulate the optimization problem as a Markov decision process (MDP) where the small-timescale resource allocation decisions generated by an improved GA are taken as the states and input into a centralized LSTM-DDPG agent to generate the service caching decision for the large-timescale. Simulation results demonstrate that our proposed algorithm outperforms the baseline algorithms in terms of the average QoS and cache switching cost.

In 1954, Alston S. Householder published Principles of Numerical Analysis, one of the first modern treatments on matrix decomposition that favored a (block) LU decomposition-the factorization of a matrix into the product of lower and upper triangular matrices. And now, matrix decomposition has become a core technology in machine learning, largely due to the development of the back propagation algorithm in fitting a neural network. The sole aim of this survey is to give a self-contained introduction to concepts and mathematical tools in numerical linear algebra and matrix analysis in order to seamlessly introduce matrix decomposition techniques and their applications in subsequent sections. However, we clearly realize our inability to cover all the useful and interesting results concerning matrix decomposition and given the paucity of scope to present this discussion, e.g., the separated analysis of the Euclidean space, Hermitian space, Hilbert space, and things in the complex domain. We refer the reader to literature in the field of linear algebra for a more detailed introduction to the related fields.

Games and simulators can be a valuable platform to execute complex multi-agent, multiplayer, imperfect information scenarios with significant parallels to military applications: multiple participants manage resources and make decisions that command assets to secure specific areas of a map or neutralize opposing forces. These characteristics have attracted the artificial intelligence (AI) community by supporting development of algorithms with complex benchmarks and the capability to rapidly iterate over new ideas. The success of artificial intelligence algorithms in real-time strategy games such as StarCraft II have also attracted the attention of the military research community aiming to explore similar techniques in military counterpart scenarios. Aiming to bridge the connection between games and military applications, this work discusses past and current efforts on how games and simulators, together with the artificial intelligence algorithms, have been adapted to simulate certain aspects of military missions and how they might impact the future battlefield. This paper also investigates how advances in virtual reality and visual augmentation systems open new possibilities in human interfaces with gaming platforms and their military parallels.

Since deep neural networks were developed, they have made huge contributions to everyday lives. Machine learning provides more rational advice than humans are capable of in almost every aspect of daily life. However, despite this achievement, the design and training of neural networks are still challenging and unpredictable procedures. To lower the technical thresholds for common users, automated hyper-parameter optimization (HPO) has become a popular topic in both academic and industrial areas. This paper provides a review of the most essential topics on HPO. The first section introduces the key hyper-parameters related to model training and structure, and discusses their importance and methods to define the value range. Then, the research focuses on major optimization algorithms and their applicability, covering their efficiency and accuracy especially for deep learning networks. This study next reviews major services and toolkits for HPO, comparing their support for state-of-the-art searching algorithms, feasibility with major deep learning frameworks, and extensibility for new modules designed by users. The paper concludes with problems that exist when HPO is applied to deep learning, a comparison between optimization algorithms, and prominent approaches for model evaluation with limited computational resources.

Clustering is one of the most fundamental and wide-spread techniques in exploratory data analysis. Yet, the basic approach to clustering has not really changed: a practitioner hand-picks a task-specific clustering loss to optimize and fit the given data to reveal the underlying cluster structure. Some types of losses---such as k-means, or its non-linear version: kernelized k-means (centroid based), and DBSCAN (density based)---are popular choices due to their good empirical performance on a range of applications. Although every so often the clustering output using these standard losses fails to reveal the underlying structure, and the practitioner has to custom-design their own variation. In this work we take an intrinsically different approach to clustering: rather than fitting a dataset to a specific clustering loss, we train a recurrent model that learns how to cluster. The model uses as training pairs examples of datasets (as input) and its corresponding cluster identities (as output). By providing multiple types of training datasets as inputs, our model has the ability to generalize well on unseen datasets (new clustering tasks). Our experiments reveal that by training on simple synthetically generated datasets or on existing real datasets, we can achieve better clustering performance on unseen real-world datasets when compared with standard benchmark clustering techniques. Our meta clustering model works well even for small datasets where the usual deep learning models tend to perform worse.