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In general insurance, claims are often lower-truncated and right-censored because insurance contracts may involve deductibles and maximal covers. Most classical statistical models are not (directly) suited to model lower-truncated and right-censored claims. A surprisingly flexible family of distributions that can cope with lower-truncated and right-censored claims is the class of MBBEFD distributions that originally has been introduced by Bernegger (1997) for reinsurance pricing, but which has not gained much attention outside the reinsurance literature. Interestingly, in general insurance, we mainly rely on unimodal skewed densities, whereas the reinsurance literature typically proposes monotonically decreasing densities within the MBBEFD class. We show that this class contains both types of densities, and we extend it to a bigger family of distribution functions suitable for modeling lower-truncated and right-censored claims. In addition, we discuss how changes in the deductible or the maximal cover affect the chosen distributions.

Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel learning (MKL) has shown to be a flexible and valid approach to consider the diverse nature of multi-omics inputs, despite being an underused tool in genomic data mining.We provide novel MKL approaches based on different kernel fusion strategies.To learn from the meta-kernel of input kernels, we adaptedunsupervised integration algorithms for supervised tasks with support vector machines.We also tested deep learning architectures for kernel fusion and classification.The results show that MKL-based models can compete with more complex, state-of-the-art, supervised multi-omics integrative approaches. Multiple kernel learning offers a natural framework for predictive models in multi-omics genomic data. Our results offer a direction for bio-data mining research and further development of methods for heterogeneous data integration.

Causal inference on the average treatment effect (ATE) using non-probability samples, such as electronic health records (EHR), faces challenges from sample selection bias and high-dimensional covariates. This requires considering a selection model alongside treatment and outcome models that are typical ingredients in causal inference. This paper considers integrating large non-probability samples with external probability samples from a design survey, addressing moderately high-dimensional confounders and variables that influence selection. In contrast to the two-step approach that separates variable selection and debiased estimation, we propose a one-step plug-in doubly robust (DR) estimator of the ATE. We construct a novel penalized estimating equation by minimizing the squared asymptotic bias of the DR estimator. Our approach facilitates ATE inference in high-dimensional settings by ignoring the variability in estimating nuisance parameters, which is not guaranteed in conventional likelihood approaches with non-differentiable L1-type penalties. We provide a consistent variance estimator for the DR estimator. Simulation studies demonstrate the double robustness of our estimator under misspecification of either the outcome model or the selection and treatment models, as well as the validity of statistical inference under penalized estimation. We apply our method to integrate EHR data from the Michigan Genomics Initiative with an external probability sample.

Quantum hypothesis testing has been traditionally studied from the information-theoretic perspective, wherein one is interested in the optimal decay rate of error probabilities as a function of the number of samples of an unknown state. In this paper, we study the sample complexity of quantum hypothesis testing, wherein the goal is to determine the minimum number of samples needed to reach a desired error probability. By making use of the wealth of knowledge that already exists in the literature on quantum hypothesis testing, we characterize the sample complexity of binary quantum hypothesis testing in the symmetric and asymmetric settings, and we provide bounds on the sample complexity of multiple quantum hypothesis testing. In more detail, we prove that the sample complexity of symmetric binary quantum hypothesis testing depends logarithmically on the inverse error probability and inversely on the negative logarithm of the fidelity. As a counterpart of the quantum Stein's lemma, we also find that the sample complexity of asymmetric binary quantum hypothesis testing depends logarithmically on the inverse type~II error probability and inversely on the quantum relative entropy. Finally, we provide lower and upper bounds on the sample complexity of multiple quantum hypothesis testing, with it remaining an intriguing open question to improve these bounds.

This paper deals with Hermite osculatory interpolating splines. For a partition of a real interval endowed with a refinement consisting in dividing each subinterval into two small subintervals, we consider a space of smooth splines with additional smoothness at the vertices of the initial partition, and of the lowest possible degree. A normalized B-spline-like representation for the considered spline space is provided. In addition, several quasi-interpolation operators based on blossoming and control polynomials have also been developed. Some numerical tests are presented and compared with some recent works to illustrate the performance of the proposed approach.

The increasing advancements in the field of machine learning have led to the development of numerous applications that effectively address a wide range of problems with accurate predictions. However, in certain cases, accuracy alone may not be sufficient. Many real-world problems also demand explanations and interpretability behind the predictions. One of the most popular interpretable models that are classification rules. This work aims to propose an incremental model for learning interpretable and balanced rules based on MaxSAT, called IMLIB. This new model was based on two other approaches, one based on SAT and the other on MaxSAT. The one based on SAT limits the size of each generated rule, making it possible to balance them. We suggest that such a set of rules seem more natural to be understood compared to a mixture of large and small rules. The approach based on MaxSAT, called IMLI, presents a technique to increase performance that involves learning a set of rules by incrementally applying the model in a dataset. Finally, IMLIB and IMLI are compared using diverse databases. IMLIB obtained results comparable to IMLI in terms of accuracy, generating more balanced rules with smaller sizes.

We propose a method for obtaining parsimonious decompositions of networks into higher order interactions which can take the form of arbitrary motifs.The method is based on a class of analytically solvable generative models, where vertices are connected via explicit copies of motifs, which in combination with non-parametric priors allow us to infer higher order interactions from dyadic graph data without any prior knowledge on the types or frequencies of such interactions. Crucially, we also consider 'degree--corrected' models that correctly reflect the degree distribution of the network and consequently prove to be a better fit for many real world--networks compared to non-degree corrected models. We test the presented approach on simulated data for which we recover the set of underlying higher order interactions to a high degree of accuracy. For empirical networks the method identifies concise sets of atomic subgraphs from within thousands of candidates that cover a large fraction of edges and include higher order interactions of known structural and functional significance. The method not only produces an explicit higher order representation of the network but also a fit of the network to analytically tractable models opening new avenues for the systematic study of higher order network structures.

The univariate dimension reduction (UDR) method stands as a way to estimate the statistical moments of the output that is effective in a large class of uncertainty quantification (UQ) problems. UDR's fundamental strategy is to approximate the original function using univariate functions so that the UQ cost only scales linearly with the dimension of the problem. Nonetheless, UDR's effectiveness can diminish when uncertain inputs have high variance, particularly when assessing the output's second and higher-order statistical moments. This paper proposes a new method, gradient-enhanced univariate dimension reduction (GUDR), that enhances the accuracy of UDR by incorporating univariate gradient function terms into the UDR approximation function. Theoretical results indicate that the GUDR approximation is expected to be one order more accurate than UDR in approximating the original function, and it is expected to generate more accurate results in computing the output's second and higher-order statistical moments. Our proposed method uses a computational graph transformation strategy to efficiently evaluate the GUDR approximation function on tensor-grid quadrature inputs, and use the tensor-grid input-output data to compute the statistical moments of the output. With an efficient automatic differentiation method to compute the gradients, our method preserves UDR's linear scaling of computation time with problem dimension. Numerical results show that the GUDR is more accurate than UDR in estimating the standard deviation of the output and has a performance comparable to the method of moments using a third-order Taylor series expansion.

Decision making and learning in the presence of uncertainty has attracted significant attention in view of the increasing need to achieve robust and reliable operations. In the case where uncertainty stems from the presence of adversarial attacks this need is becoming more prominent. In this paper we focus on linear and nonlinear classification problems and propose a novel adversarial training method for robust classifiers, inspired by Support Vector Machine (SVM) margins. We view robustness under a data driven lens, and derive finite sample complexity bounds for both linear and non-linear classifiers in binary and multi-class scenarios. Notably, our bounds match natural classifiers' complexity. Our algorithm minimizes a worst-case surrogate loss using Linear Programming (LP) and Second Order Cone Programming (SOCP) for linear and non-linear models. Numerical experiments on the benchmark MNIST and CIFAR10 datasets show our approach's comparable performance to state-of-the-art methods, without needing adversarial examples during training. Our work offers a comprehensive framework for enhancing binary linear and non-linear classifier robustness, embedding robustness in learning under the presence of adversaries.

In large-scale systems there are fundamental challenges when centralised techniques are used for task allocation. The number of interactions is limited by resource constraints such as on computation, storage, and network communication. We can increase scalability by implementing the system as a distributed task-allocation system, sharing tasks across many agents. However, this also increases the resource cost of communications and synchronisation, and is difficult to scale. In this paper we present four algorithms to solve these problems. The combination of these algorithms enable each agent to improve their task allocation strategy through reinforcement learning, while changing how much they explore the system in response to how optimal they believe their current strategy is, given their past experience. We focus on distributed agent systems where the agents' behaviours are constrained by resource usage limits, limiting agents to local rather than system-wide knowledge. We evaluate these algorithms in a simulated environment where agents are given a task composed of multiple subtasks that must be allocated to other agents with differing capabilities, to then carry out those tasks. We also simulate real-life system effects such as networking instability. Our solution is shown to solve the task allocation problem to 6.7% of the theoretical optimal within the system configurations considered. It provides 5x better performance recovery over no-knowledge retention approaches when system connectivity is impacted, and is tested against systems up to 100 agents with less than a 9% impact on the algorithms' performance.