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In this article, we aim to provide a general and complete understanding of semi-supervised (SS) causal inference for treatment effects. Specifically, we consider two such estimands: (a) the average treatment effect and (b) the quantile treatment effect, as prototype cases, in an SS setting, characterized by two available data sets: (i) a labeled data set of size $n$, providing observations for a response and a set of high dimensional covariates, as well as a binary treatment indicator; and (ii) an unlabeled data set of size $N$, much larger than $n$, but without the response observed. Using these two data sets, we develop a family of SS estimators which are ensured to be: (1) more robust and (2) more efficient than their supervised counterparts based on the labeled data set only. Beyond the 'standard' double robustness results (in terms of consistency) that can be achieved by supervised methods as well, we further establish root-n consistency and asymptotic normality of our SS estimators whenever the propensity score in the model is correctly specified, without requiring specific forms of the nuisance functions involved. Such an improvement of robustness arises from the use of the massive unlabeled data, so it is generally not attainable in a purely supervised setting. In addition, our estimators are shown to be semi-parametrically efficient as long as all the nuisance functions are correctly specified. Moreover, as an illustration of the nuisance estimators, we consider inverse-probability-weighting type kernel smoothing estimators involving unknown covariate transformation mechanisms, and establish in high dimensional scenarios novel results on their uniform convergence rates, which should be of independent interest. Numerical results on both simulated and real data validate the advantage of our methods over their supervised counterparts with respect to both robustness and efficiency.

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Super-Resolution is the technique to improve the quality of a low-resolution photo by boosting its plausible resolution. The computer vision community has extensively explored the area of Super-Resolution. However, previous Super-Resolution methods require vast amounts of data for training which becomes problematic in domains where very few low-resolution, high-resolution pairs might be available. One such area is statistical downscaling, where super-resolution is increasingly being used to obtain high-resolution climate information from low-resolution data. Acquiring high-resolution climate data is extremely expensive and challenging. To reduce the cost of generating high-resolution climate information, Super-Resolution algorithms should be able to train with a limited number of low-resolution, high-resolution pairs. This paper tries to solve the aforementioned problem by introducing a semi-supervised way to perform super-resolution that can generate sharp, high-resolution images with as few as 500 paired examples. The proposed semi-supervised technique can be used as a plug-and-play module with any supervised GAN-based Super-Resolution method to enhance its performance. We quantitatively and qualitatively analyze the performance of the proposed model and compare it with completely supervised methods as well as other unsupervised techniques. Comprehensive evaluations show the superiority of our method over other methods on different metrics. We also offer the applicability of our approach in statistical downscaling to obtain high-resolution climate images.

Covariance estimation for matrix-valued data has received an increasing interest in applications. Unlike previous works that rely heavily on matrix normal distribution assumption and the requirement of fixed matrix size, we propose a class of distribution-free regularized covariance estimation methods for high-dimensional matrix data under a separability condition and a bandable covariance structure. Under these conditions, the original covariance matrix is decomposed into a Kronecker product of two bandable small covariance matrices representing the variability over row and column directions. We formulate a unified framework for estimating bandable covariance, and introduce an efficient algorithm based on rank one unconstrained Kronecker product approximation. The convergence rates of the proposed estimators are established, and the derived minimax lower bound shows our proposed estimator is rate-optimal under certain divergence regimes of matrix size. We further introduce a class of robust covariance estimators and provide theoretical guarantees to deal with heavy-tailed data. We demonstrate the superior finite-sample performance of our methods using simulations and real applications from a gridded temperature anomalies dataset and a S&P 500 stock data analysis.

This paper considers the problem of inference in cluster randomized experiments when cluster sizes are non-ignorable. Here, by a cluster randomized experiment, we mean one in which treatment is assigned at the level of the cluster; by non-ignorable cluster sizes we mean that "large" clusters and "small" clusters may be heterogeneous, and, in particular, the effects of the treatment may vary across clusters of differing sizes. In order to permit this sort of flexibility, we consider a sampling framework in which cluster sizes themselves are random. In this way, our analysis departs from earlier analyses of cluster randomized experiments in which cluster sizes are treated as non-random. We distinguish between two different parameters of interest: the equally-weighted cluster-level average treatment effect, and the size-weighted cluster-level average treatment effect. For each parameter, we provide methods for inference in an asymptotic framework where the number of clusters tends to infinity and treatment is assigned using simple random sampling. We additionally permit the experimenter to sample only a subset of the units within each cluster rather than the entire cluster and demonstrate the implications of such sampling for some commonly used estimators. A small simulation study shows the practical relevance of our theoretical results.

Guitar tablature transcription is an important but understudied problem within the field of music information retrieval. Traditional signal processing approaches offer only limited performance on the task, and there is little acoustic data with transcription labels for training machine learning models. However, guitar transcription labels alone are more widely available in the form of tablature, which is commonly shared among guitarists online. In this work, a collection of symbolic tablature is leveraged to estimate the pairwise likelihood of notes on the guitar. The output layer of a baseline tablature transcription model is reformulated, such that an inhibition loss can be incorporated to discourage the co-activation of unlikely note pairs. This naturally enforces playability constraints for guitar, and yields tablature which is more consistent with the symbolic data used to estimate pairwise likelihoods. With this methodology, we show that symbolic tablature can be used to shape the distribution of a tablature transcription model's predictions, even when little acoustic data is available.

We study efficient estimation of an interventional mean associated with a point exposure treatment under a causal graphical model represented by a directed acyclic graph without hidden variables. Under such a model, it may happen that a subset of the variables are uninformative in that failure to measure them neither precludes identification of the interventional mean nor changes the semiparametric variance bound for regular estimators of it. We develop a set of graphical criteria that are sound and complete for eliminating all the uninformative variables so that the cost of measuring them can be saved without sacrificing estimation efficiency, which could be useful when designing a planned observational or randomized study. Further, we construct a reduced directed acyclic graph on the set of informative variables only. We show that the interventional mean is identified from the marginal law by the g-formula (Robins, 1986) associated with the reduced graph, and the semiparametric variance bounds for estimating the interventional mean under the original and the reduced graphical model agree. This g-formula is an irreducible, efficient identifying formula in the sense that the nonparametric estimator of the formula, under regularity conditions, is asymptotically efficient under the original causal graphical model, and no formula with such property exists that only depends on a strict subset of the variables.

Let $X^{(n)}$ be an observation sampled from a distribution $P_{\theta}^{(n)}$ with an unknown parameter $\theta,$ $\theta$ being a vector in a Banach space $E$ (most often, a high-dimensional space of dimension $d$). We study the problem of estimation of $f(\theta)$ for a functional $f:E\mapsto {\mathbb R}$ of some smoothness $s>0$ based on an observation $X^{(n)}\sim P_{\theta}^{(n)}.$ Assuming that there exists an estimator $\hat \theta_n=\hat \theta_n(X^{(n)})$ of parameter $\theta$ such that $\sqrt{n}(\hat \theta_n-\theta)$ is sufficiently close in distribution to a mean zero Gaussian random vector in $E,$ we construct a functional $g:E\mapsto {\mathbb R}$ such that $g(\hat \theta_n)$ is an asymptotically normal estimator of $f(\theta)$ with $\sqrt{n}$ rate provided that $s>\frac{1}{1-\alpha}$ and $d\leq n^{\alpha}$ for some $\alpha\in (0,1).$ We also derive general upper bounds on Orlicz norm error rates for estimator $g(\hat \theta)$ depending on smoothness $s,$ dimension $d,$ sample size $n$ and the accuracy of normal approximation of $\sqrt{n}(\hat \theta_n-\theta).$ In particular, this approach yields asymptotically efficient estimators in some high-dimensional exponential models.

In randomized experiments, the actual treatments received by some experimental units may differ from their treatment assignments. This non-compliance issue often occurs in clinical trials, social experiments, and the applications of randomized experiments in many other fields. Under certain assumptions, the average treatment effect for the compliers is identifiable and equal to the ratio of the intention-to-treat effects of the potential outcomes to that of the potential treatment received. To improve the estimation efficiency, we propose three model-assisted estimators for the complier average treatment effect in randomized experiments with a binary outcome. We study their asymptotic properties, compare their efficiencies with that of the Wald estimator, and propose the Neyman-type conservative variance estimators to facilitate valid inferences. Moreover, we extend our methods and theory to estimate the multiplicative complier average treatment effect. Our analysis is randomization-based, allowing the working models to be misspecified. Finally, we conduct simulation studies to illustrate the advantages of the model-assisted methods and apply these analysis methods in a randomized experiment to evaluate the effect of academic services or incentives on academic performance.

In this paper we study the finite sample and asymptotic properties of various weighting estimators of the local average treatment effect (LATE), several of which are based on Abadie (2003)'s kappa theorem. Our framework presumes a binary endogenous explanatory variable ("treatment") and a binary instrumental variable, which may only be valid after conditioning on additional covariates. We argue that one of the Abadie estimators, which we show is weight normalized, is likely to dominate the others in many contexts. A notable exception is in settings with one-sided noncompliance, where certain unnormalized estimators have the advantage of being based on a denominator that is bounded away from zero. We use a simulation study and three empirical applications to illustrate our findings. In applications to causal effects of college education using the college proximity instrument (Card, 1995) and causal effects of childbearing using the sibling sex composition instrument (Angrist and Evans, 1998), the unnormalized estimates are clearly unreasonable, with "incorrect" signs, magnitudes, or both. Overall, our results suggest that (i) the relative performance of different kappa weighting estimators varies with features of the data-generating process; and that (ii) the normalized version of Tan (2006)'s estimator may be an attractive alternative in many contexts. Applied researchers with access to a binary instrumental variable should also consider covariate balancing or doubly robust estimators of the LATE.

The inverse probability (IPW) and doubly robust (DR) estimators are often used to estimate the average causal effect (ATE), but are vulnerable to outliers. The IPW/DR median can be used for outlier-resistant estimation of the ATE, but the outlier resistance of the median is limited and it is not resistant enough for heavy contamination. We propose extensions of the IPW/DR estimators with density power weighting, which can eliminate the influence of outliers almost completely. The outlier resistance of the proposed estimators is evaluated through the unbiasedness of the estimating equations. Unlike the median-based methods, our estimators are resistant to outliers even under heavy contamination. Interestingly, the naive extension of the DR estimator requires bias correction to keep the double robustness even under the most tractable form of contamination. In addition, the proposed estimators are found to be highly resistant to outliers in more difficult settings where the contamination ratio depends on the covariates. The outlier resistance of our estimators from the viewpoint of the influence function is also favorable. Our theoretical results are verified via Monte Carlo simulations and real data analysis. The proposed methods were found to have more outlier resistance than the median-based methods and estimated the potential mean with a smaller error than the median-based methods.

Models for dependent data are distinguished by their targets of inference. Marginal models are useful when interest lies in quantifying associations averaged across a population of clusters. When the functional form of a covariate-outcome association is unknown, flexible regression methods are needed to allow for potentially non-linear relationships. We propose a novel marginal additive model (MAM) for modelling cluster-correlated data with non-linear population-averaged associations. The proposed MAM is a unified framework for estimation and uncertainty quantification of a marginal mean model, combined with inference for between-cluster variability and cluster-specific prediction. We propose a fitting algorithm that enables efficient computation of standard errors and corrects for estimation of penalty terms. We demonstrate the proposed methods in simulations and in application to (i) a longitudinal study of beaver foraging behaviour, and (ii) a spatial analysis of Loaloa infection in West Africa. R code for implementing the proposed methodology is available at //github.com/awstringer1/mam.

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